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The early host response to an infection is dependent on an efficient innate immune system. The human contact system once activated at a bacterial surface results in the induction of proinflammatory reactions and the release of antimicrobial peptides, However, under severe conditions its systemic activation A may evoke the generation of pathologic levels of kinins and a consumption of contact facto

The risk of hip fracture rises rapidly with age, and is particularly high in women. This increase in fracture risk reflects both the age-related change in the risk of falling and decrements in the strength of the proximal femur. To better understand the extent to which proximal femoral density, structure and strength change with age as a function of gender, we have carried out a longitudinal analy

This chapter highlights user perspectives related to the development of ICT and the launching of political strategies to involve users in the IT society. Strategies are discussed in relation to cooperation between technical and social scientists. The author points to the fact that the diffrences between various theoretical understandings of the interaction between technology and social change tend

Brown dwarf atmospheres form molecules, then high temperature condensates (corundum, titanates, silicates, and iron compounds), and then low temperature condensates (ices) as they cool down over time. These produce large opacities which govern entirely their spectral energy distribution. Just as it is important to know molecular opacities (TiO, H2O, CH4, etc.) with accuracy, it is imperative to un

Return migration is an important phenomenon that involves a large share of all migrants, and has great potential for the enhancement of economic development, for instance through remittances and investments by migrants who are still abroad, and “brain gain” when migrants return with working experience from their former host countries. This paper deals with return migration, by refugee immigrants a

Asthma is a chronic inflammatory disease affecting over 300 million people worldwide. The common association with allergic rhinitis and the presence of proinflammatory cells and mediators in the circulation of patients qualify asthma as a systemic disease. This characteristic and the fact that the gold-standard therapy for persistent asthma, inhaled corticosteroids, cannot suppress all components

Observations of the ultra-sharp-lined, chemically peculiar star chi Lupi taken by the Goddard High Resolution Spectrograph in echelle mode are presented. Thirty-six intervals of the spectral region between 1249 and 2688 Angstrom are covered with resolving powers in the range 75,000-93,000. Line identifications are provided, and the observed spectra are compared with synthetic spectra calculated us

Popular Abstract in French L'inquiétude grandit quant à la perte de la biodiversité liée aux changements d'utilisation des terres, l’effet de cette perte sur les services écosystémiques fournis par les communautés naturelles et semi-naturelles et, finalement, la menace que cela pourrait entraîner sur le bien-être de l’Homme. Ce travail de thèse examine l'impact de l'utilisation des terres présenteConcerns are increasing about the loss of biodiversity under land use change and how this will affect the ecosystem services provided by natural and semi-natural communities and consequently how this will threaten human well-being. The thesis examines the impact of present and past land use on different aspects of biodiversity; namely species diversity, traits and functional diversity and on ecos

Researchers often aim to make correct inferences both about that which is actually studied (internal validity) and about what the results generalize to (external validity). The language of internal and external validity is not used by everyone, but many of us would agree that intuitively the distinction makes a lot of sense. Two claims are commonly made with respect to internal and external validi

ABSTRACT Optimal breeding of mice is very important in biomedical science today. The understanding why some strains breed better and some worse enable scientists to create better in vivo models for human diseases. The aim of this thesis was to identify and characterize new genetic regions linked to reproductive performance and autoimmune inflammation in female mice. Collagen-induced arthritis (CIA

Ta igen dig – på arbetstid Ny metod botar avhandlingsangst Institutioner väljer bort kött Stjärnräknare LUNDS UNIVERSITETS MAGASIN | NR 1 | 2019 ANLITAR ALLMÄNHETEN TILL MASSEXPERIMENT 2 LUM NR 1 | 2019 LUM NR 1 | 2019 3 ”Du måste vara mellan 18–60 år gammal, icke-rökare, inte vara gravid och du får inte ha några luftvägssjukdomar, eksem eller öppna sår.” Önskemålen i annon- sen kan tyckas lite ud

https://www.lu.se/sites/www.lu.se/files/lunds-universitets-magasin1-2019.pdf - 2026-07-09

Glucagon is the principal glucose-elevating hormone that forms the first-line defence against hypoglycaemia. Along with insulin, glucagon also plays a key role in maintaining systemic glucose homeostasis. The cells that secrete glucagon, pancreatic α-cells, are electrically excitable cells and use electrical activity to couple its hormone secretion to changes in ambient glucose levels. Exactly how

This chapter explores the relevance of the Christian tradition to contemporary debates on solidarity in international law and human rights. It positions the genealogy of solidarity within early Christian writings in which the western theological concepts of suffering, love, and salvation are detailed. Linking the Pauline doctrine and writings of early theologians to the processes of modernity – of

Life and afterlife in the Nordic Bronze Age contains some of the papers presented at the 15th Nordic Bronze Age Symposium, June 2019. Over these five days approximately 100 researchers of the Bronze Age gathered to present papers and discuss traditional research questions as well as current topics that have been brought about by the breakthrough of the third scientific revolution of archaeology ov

The Cherenkov Telescope Array (CTA) will be the next generation very-high-energy gamma-ray observatory. CTA is expected to provide substantial improvement in accuracy and sensitivity with respect to existing instruments thanks to a tenfold increase in the number of telescopes and their state-of-the-art design. Detailed Monte Carlo simulations are used to further optimise the number of telescopes a

BACKGROUND: Prostate-specific antigen (PSA) occurs in different molecular forms in serum: free PSA (fPSA) and complexed PSA (cPSA), the sum of which corresponds to total PSA (tPSA). In addition to tPSA, percent fPSA is widely used in the detection of prostate cancer. Free PSA, approximately 28 kDa, is eliminated by glomerular filtration. Previous data showed that men with end-stage renal dysfuncti