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Dendritic cells (DC) are a heterogeneous lineage of bone-marrow-derived leukocytes that serve as the link between innate and adaptive immunity. They are professional antigen-presenting cells that play an important protective and regulatory role in both health and disease. This thesis is based upon six original papers that deal with the function and transcription of human DCs, with focus on their r

I will start out with an overview of common assumptions on the impact of free trade on the environment – assumptions which, very much like the first part of Lamy’s statement, are all-encompassing and deterministic. From there, I will narrow down the scope of examination to specific and immediate hardware-to-hardware impacts: akin to the second part of the above statement, the emphasis shall be put

China's transition from planned to market economy is at present one of the topics most discussed among researchers. According to almost any version of mainstream property rights theory, the rapid privatization or what has been described as the "East European model" basically represents the correct approach to transformation, while the gradual transition, or the "Chinese model", should represent a

Objective: Individual-based studies on restricted geographical settings have suggested that nonsteroidal anti-inflammatory drugs (NSAIDs) may precipitate congestive heart failure. As NSAID use is very extensive, it might increase the occurrence of symptomatic heart failure in the general population. Therefore, in order to study the impact of NSAID utilisation (prescribed and over the counter) on h

Thiazolidinediones are antidiabetic agents that decrease insulin resistance. Emerging evidence indicates that they present beneficial effects for the vasculature beyond glycemic control. The aim of this open-label observational study was to determine the effect of the thiazolidinedione rosiglitazone on novel cardiovascular risk factors, namely, lipoprotein(a) [Lp(a)], C-reactive protein (CRP), hom

BACKGROUND: Studies of cardiovascular deconditioning are primarily carried out after experimental bed rest. No previous study has followed the cardiovascular effects of decreased and resumed physical activity in athletes after acute physical injury and convalescence. Anterior cruciate ligament (ACL) injury causes a significantly decreased activity level over a long period, making it an ideal model

Background: the link between the vitamin D endocrine axis and frailty remains undefined, with few studies examining the joint effect of vitamin D and parathyroid hormone (PTH) levels. Our objective was to determine the association of frailty with serum 25-hydroxyvitamin D (25(OH) D) and PTH. Setting: cross-sectional analysis within the European Male Ageing Study (EMAS). Participants: a total of 1,

This article explores three entrepreneurial ventures that have evolved in proximity to online piracy. In reviewing the respective cases of Spotify, Skype, and The Pirate Bay, the argument outlines the radically divergent strategies with which the entrepreneurs have sought to legitimise their ventures and underlying technologies. The article concludes that 1) the context of practices labelled “pira

Water exchange on Pt(H20)42+ and trans-PtCI2(H20)2 has been studied by means of a new oxygen18 tracing technique. The exchange between a platinum(II) complex and 018-enriched water has been rapidly quenched by addition of excess chlorine, which gives a substitution-inert platinum(IV) complex. The time-dependent oxygen16/oxygen18 distributions of the platinum(II) complexes are obtained from the 195

The landscape composition in Sweden has drastically changed during recent years. Intensified farming and forestry has led to reduced areas valuable for biodiversity and a decline of biodiversity across many organism groups. In Sweden almost 30% of all day-living butterflies are considered threatened. Habitat creation as a by-product of anthropogenic activities may provide new habitats for species

Background: This paper discusses whether baseline demographic, socio-economic, health variables, length of follow-up and method of contacting the participants predict non-response to the invitation for a second assessment of lifestyle factors and body weight in the European multi-center EPIC-PANACEA study. Methods: Over 500.000 participants from several centers in ten European countries recruited

The Image of Sweden abroad usually comes with positive connotations. Some of Sweden’s perceived strengths, e.g. being open, authentic, caring, and innovative, are represented in the Strategy for the Image of Sweden (2013). However, changing circumstances, such as the implementation of internal border controls as a result of the migration crisis beginning in autumn 2015, along with a changing polit

The state of the environment and human’s impact on the environment has been widely acknowledged and discussed over the past years. The EU realized there was a need for environmental regulations and laws in 1972 and in 1993 the environment became an official part of their politics. The aim of this paper has been to find out whether it is possible to both increase trade and at the same time decrease

I Sverige bor ca 85% av befolkningen i stan, vilket har genererat stora mängder trafik i städerna. För att klara av den ökade trafiken, minska olägenheterna trafiken skapar och uppnå effektiv mobilitet erbjuder ITS, intelligenta transportsystem, och IoT, internet of things, applikationer olika digitala hjälpmedel för att lösa de begynnande problemen. Syftet för detta arbete har varit att ta redaAbout 85% of Sweden’s population live in a city, which have resulted in great amounts of traffic in the cities. To deal with the increasing traffic, decrease the disadvantages that the traffic creates and achieve effective mobility ITS, Intelligent transport system, and IoT, internet of things applications offer digital tools to solve the rising issues. The purpose of the study has been to find

In this essay, the feminine ideals in Virginia Woolf’s To the Lighthouse, Doris Lessing’s “To Room Nineteen” and Alice Munro’s “Too Much Happiness” are analysed and compared to the ideal of the Angel in the House – an ideal that originates from Coventry Patmore’s poem The Angel in the House and was popularised by Virginia Woolf’s paper “Professions for Women”. In addition, the consequences of this