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Joint diseases are often characterized by inflammatory processes that result in pathological changes in joint tissues, including cartilage degradation and release of components into the synovial fluid. The complement system plays a central role in promoting the inflammation. Because several cartilage proteins are known to interact with complement, causing either activation or inhibition of the sys

CONTEXT: Screening of autoimmune thyroid disease in children and young adults with Type 1 diabetes is important but vary greatly between clinics.OBJECTIVE: The aim was to determine the predictive value of thyroid autoantibodies, thyroid function, islet autoantibodies, and HLA- DQ at diagnosis of Type 1 diabetes for autoimmune thyroid disease during subsequent follow-up.SETTING: 43 Paediatric Endoc

The past few decades have seen an increasing demand for environmental information on which to make more informed decisions, strengthened by several international calls for improving available environmental information. In a democratic South Africa, the involvement of people in policy and decision-making processes has led to an even greater need for accessible information. In response to this deman

Preterm human neonates, contrary to preterm piglets, obtain immunoglobulins from their mothers via the placenta during intrauterine development. However, one should note that the majority of trans-placental transfer of immunoglobulins in humans takes place during the last trimester of pregnancy. It is also known that the feeding of limited amounts of colostrum or systemic infusion of small amounts

The article summarizes the results of work since 2010 to develop non- destructive energy dispersive X-ray fluorescence analysis (EDXRF) as a non-destructive method for determining the provenience of flint in northern Europe. Some 40 localities from Sweden, Denmark, Germany, Poland, and Ukraine have been sampled and analyzed. Trace elements have not proven particularly effective in drawing distinct

Maintenance Process Course Catalogue The Basics Optical Sectioning Techniques + Focus on cLSM Introduction into „blur-free“ Microscopy Dr. Sebastian Gliem Training Application and Support Center – TASC Carl Zeiss Microscopy GmbH O sl o Tr ai ni ng 20 17 What is this talk all about? 4/5/2018 3Carl Zeiss Microscopy GmbH, Sebastian Gliem In tro du ct io n • This is a talk about microscopy techniques

https://www.ludc.lu.se/sites/ludc.lu.se/files/optical_sectioning_techniques_zeiss_training_slides.pdf - 2026-06-01

The brain has a tremendous capacity to adapt (i.e., plasticity) to environmental changes or injury. This capacity decreases with age but is never lost. The goal of sensory relearning is to improve hand function by using the dynamic capacity of the brain with the use of guided plasticity (i.e., plasticity used for a therapeutic purpose). After a peripheral nerve injury, no nerve signals are sent fr

BACKGROUND: In patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI) and who are treated with direct oral anticoagulants (DOACs), dual antithrombotic treatment without aspirin is recommended. Evidence comparing P2Y 12 inhibitor strategies in this setting is limited. AIMS: This study aimed to compare outcomes with ticagrelor versus clopidogrel as part of du

Background: Progressive respiratory failure is the leading cause of death in patients with severe COVID-19. Histopathological findings in acute severe COVID-19 are foremost based on post-mortem findings. On computed tomography (CT), acute COVID-19 pneumonia is characterized by ground-glass opacities (GGOs) and, later, by a crazy-paving pattern (CPP) and consolidations. Purpose: To investigate if C

Glutamic acid decarboxylase 65 (GAD65) and autoantibodies specific for GAD65 (GADA) are associated with autoimmune diseases including Stiff Person Syndrome (SPS) and Type 1 diabetes (T1D). GADA is recognized as a biomarker of value for clinical diagnosis and prognostication in these diseases. Nonetheless, it remains medically interesting to develop sensitive and specific assays to detect GAD65 pre

D EV EL O PM EN T 507RESEARCH ARTICLE INTRODUCTION The mesencephalic dopaminergic (mesDA) neurons have been studied extensively owing to their involvement in Parkinson’s disease, as well as in psychiatric and affective disorders. The mesDA neurons are located in the substantia nigra (SN, cell group A9), the ventral tegmental area (VTA, cell group A10) and the retro-rubral area (RRA, cell group A8)

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/andersson_et_al_development_2006.pdf - 2026-06-01

https://www.mhm.lu.se/en/sites/mhm.lu.se.en/files/engpianovocalguitarrecharp.pdf - 2026-06-01

Due to the rapid climate change, drivers are now more likely to drive in severe weather conditions than before. In bad weather, drivers have no option but to cope with a very unusual environment, increasing the likelihood that an accident will transpire. Therefore, it is important to find ways to operate vehicle systems more easily and safely during bad weather. In this study, we investigated 6 in

This study analyzed Japanese mandible movements using a recently developed technique, the MARRYS helmet [Gudmundsson et al., Interspeech (2024)]. Data were collected from 9 first language and 10 second language (Mandarin Chinese) speakers of Japanese. The speech materials included three sentences composed entirely of /a/ vowels, one neutral sentence and three focus sentences with emphasis on diffe

BACKGROUND: Atrial fibrillation (AF) often complicates ST-segment–elevation myocardial infarction (STEMI), but data on AF recurrence after first-ever AF during STEMI are scarce. We aimed at assessing the risk of AF recurrence after first-ever transient AF during admission for STEMI. METHODS: We performed a single-center, register-based cohort study. Patients with STEMI discharged alive after prima

Additive manufacturing (AM), particularly Laser Powder Bed Fusion, produces surfaces with unique, randomly distributed spherical roughness that significantly influences heat transfer and pressure loss. This study models AM roughness using a statistical distribution of spheres and performs high-fidelity simulations at a bulk Reynolds number of 12,000 to evaluate heat transfer on a rough pipe. Stati

Aims: Superficial CD34-positive fibroblastic tumour (SCD34FT) is an uncommon but distinctive low-grade neoplasm of the skin and subcutis that shows frequent CADM3 expression by immunohistochemistry (IHC). In this study, prompted by an index case resembling ‘atypical fibrous histiocytoma (FH)’ that was positive for CADM3 IHC, we systematically examined a cohort of tumours previously diagnosed as ‘a

OBJECTIVE: There is growing interest in how peers' genotypes may influence health (i.e., peer social genetic effects). The authors sought to clarify the nature of peer social genetic effects on risk for drug use disorder, alcohol use disorder (AUD), major depression, and anxiety disorder. METHOD: Cox models were used with data from a population-based Swedish cohort (N=655,327). Outcomes were drug