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In this paper, a feature extraction method based on principal component analysis was developed for classification of the vascular access’s condition in hemodialysis patients. The assessment of the method was carried out by discriminating between before and after angioplasty sound recordings as well as before angioplasty and reference recordings. The results showed that when before and after angiop

Professionals who take part in the building process have long been concerned with the same environmental factors, e.g. spatial layout, capacity, and function, as well as user demography. Through the knowledge gained on the ways environmental factors affect users of buildings, the need to understand how to handle these factors has grown, due to their influence on the building process. It will be sh

Popular Abstract in Swedish Antikroppar är viktiga beståndsdelar av det naturliga immunförsvaret som skyddar oss mot smittämnen, såsom bakterier och virus. Utvecklingen av olika genetiska och biokemiska teknologier har dessutom möjliggjort användningen av antikroppar för en mängd ändmål, bl a för diagnostik och behandling av infektionssjukdomar och cancer. I denna avhandling, som bygger på fem vetAntibodies are key players of the immune system in higher vertebrates, which provide a defense against potentially lethal threats from the environment. Besides their importance in the immune defense, antibodies have a great potential as reagents in biological chemistry and diagnostics, and as therapeutic agents against both infectious diseases and cancer. Despite tremendous advances in all fields

Abstract Regnell, Astrid: Att se stjärnor på ljusa dagen. Förvandling och försoning i August Strindbergs En blå bok. Seeing stars in broad daylight. Transformation and Reconciliation in August Strindberg’s Zones of the Spirit. In this thesis a pattern of coherence is explored in August Strindberg’s Zones of the Spirit (En blå bok) – a literary work consisting of a collection of short and quite div

Popular Abstract in Swedish Ärftliga orsaker till ledgångsreumatism och Sjögrens syndrom Ett välfungerande immunförsvar är nödvändigt för att kroppen ska kunna mostå angrepp från virus, bakterier och andra mikroorganismer. Vid en autoimmun sjukdom tror man att immunförsvaret av misstag börjar angripa kroppens egna vävnader, vilket leder till att de förstörs. Hur dessa sjukdomar uppkommer känner mTo understand the pathogenesis of autoimmune diseases we have to consider the problem from different angles. Animal models provide a tool to further understand these complex diseases, as the influence of genetic and environmental factors could be limited. Moreover, modern transgenic techniques have made it possible to study the role of certain genes and gene products in the development of diseases

This paper presents a study of the main advantages of inverted decoupling in 2×2 processes. Two simulation examples and an experimental process are used to show these advantages in comparison with simplified decoupling. The study focuses on the following practical advantages: the apparent process is the same as that obtained if one loop changes to manual; bumpless transfer and anti-windup are achi

The current rapid development within work-environment research has created a considerable demand among industrial hygienists for suitable analytical methods. PIXE (particle-induced X-ray emission analysis), which was introduced in Lund in 1970, has been shown to be a feasible method for use in studying the elemental composition of aerosols. However, in some work environments, fluorine, an element

E. coli continues to be a popular host organism for production of recombinant proteins. To obtain a high volumetric productivity at the cultivation stage, it is important to achieve a high cell density and a high specific productivity per cell. In many fed-batch processes, the substrate feed rate eventually becomes limited by the oxygen transfer capacity of the bioreactor. While biomass can contin

Antibodies to citrulline-modified proteins have a high diagnostic value in rheumatoid arthritis (RA). However, their biological role in disease development is still unclear. To obtain insight into this question, a panel of mouse monoclonal antibodies was generated against a major triple helical collagen type II (CII) epitope (position 359-369; ARGLTGRPGDA) with or without arginines modified by cit

Premature prelabor rupture of the fetal membranes affects about 3% of pregnancies. The cause is usually infection, especially at earlier gestations. The prognosis and the risks of delivery are both much worse at earlier gestations. Before viable pregnancy, termination may be offered. Once the fetus is viable, steroids to mature the fetal lungs and antibiotics to reduce infection are the mainstays

A high non-specific binding of immunoglobulins to plastic surfaces was noted with a number of rat sera, when tested in an indirect 125I-labeled protein-A assay for detection of cell-surface-bound rat immunoglobulins of various classes and IgG subclasses. This type of non-specific binding was found with all types of Ig. The degree of binding varied with the type of test plate used and fluctuated wi

Neurotensin regulates both satiety and breast cancer growth in the experimental setting, but little is known about its role in the development of breast cancer or cardiometabolic disease in humans.

Gaia will observe huge numbers of binaries with a large range of periods. The present contribution tries to present some estimates of the expected number of detections and/or orbit determinations, based on simplified but large-scale simulations. The simulations have to model both a Galaxy with binaries, the instrument and observations, and the reduction programs. As in previous studies, there are

Transgenic mice were generated expressing NK1.1, an NK cell-associated receptor, under control of the human CD2 promoter. Unexpectedly, one of the founder lines, Tg66, showed a marked defect in thymic development characterized by disorganized architecture and small size. Mapping of the transgene insertion by fluorescence in situ hybridization revealed integration in chromosome 2, band G. Already f

Intranasal administration of peptide Acl-9[4Y], based on the N-terminal epitope of myelin basic protein, can induce CD4(+) T cell tolerance, and suppress experimental autoimmune encephalomyelitis induction. The peptide-induced regulatory T (PI-T-Reg) cells failed to produce IL-2, but expressed IL-10 in response to Ag and could suppress naive T cell responses in vitro. Analysis of Jak-STAT signalin

Psoriasis is a frequently occurring inflammatory skin disease characterized by thickened erythematous skin that is covered with silvery scales. It is a complex genetic disease with both heritable and environmental factors contributing to onset and severity. The CD18 hypomorphic PL/J mouse reveals reduced expression of the common chain of beta(2) integrins (CD11/CD18) and spontaneously develops a s

The aim of this study is to assess the effect that different fire exposures have on the behaviour of gypsum plasterboard assemblies with known fire resistance rating. For this purpose a series of fire tests were performed on commonly used wall assemblies. Four different small scale samples were tested under ISO 834 and HCC standard fire curves. Additionally, one assembly was tested in an enclosure

Since independence and over the years, pesticides have become a dominant feature of Bangladesh agriculture. To protect farmers' health, environment and to improve sustainability of chemical pest control quantitative understanding of farmers' behavior in pesticide use is critical. However, study on the levels of knowledge and awareness of farmers and the practices of pesticide use are often limited

To update the European League Against Rheumatism (EULAR) recommendations for vaccination in adult patients with autoimmune inflammatory rheumatic diseases (AIIRD) published in 2011. Four systematic literature reviews were performed regarding the incidence/prevalence of vaccine-preventable infections among patients with AIIRD; efficacy, immunogenicity and safety of vaccines; effect of anti-rheumati