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INTRODUCTION. The diagnosis of acute lung injury may be more robust if more accurate physiological markers can be identified. Extravascular lung water index (EVLWI) may be useful and has been shown to correlate with respiratory function and mortality in patients with sepsis and ARDS. Whether this applies to a wider population, and which index performs best, are unclear. OBJECTIVES. We hypothesized

Flexibility of the energy system plays a vital role when integrating non-dispatchable renewable energy technologies. However, flexibility of the energy system has been often discussed only focusing on the operation of the energy system. This study extends the flexibility concept considering both design and operation of the energy system. In order to achieve this, pseudo chronological scenarios use

Accurate diagnosis of histological type is important for therapy selection in lung cancer. Immunohistochemical (IHC) and histochemical stains are often used to complement morphology for definite diagnosis and are incorporated in the WHO classification. Our main aim was to compare different mucin stains and assess their value in relation to common IHC analyses in lung cancer diagnostics. Using tiss

The University of Vermont College of Medicine, in collaboration with the NHLBI, Alpha-1 Foundation, American Thoracic Society, Cystic Fibrosis Foundation, European Respiratory Society, International Society for Cellular Therapy, and the Pulmonary Fibrosis Foundation, convened a workshop, "Stem Cells and Cell Therapies in Lung Biology and Lung Diseases," held July 27 to 30, 2015, at the University

The development of functionally competent, self-tolerant T cells in the thymus is an essential prerequisite for the formation of adaptive immune responses against foreign pathogens. Thymic epithelial cells (TECs) form specialized stromal microenvironments in the cortex (cTEC) and medulla (mTEC) of the thymus that support all stages of T cell development, from the entry of thymocyte progenitors to

Identification of cancer pathways is the central goal in the cancer gene expression data analysis. A cellular automaton is a dynamic system with cells, which are uniform, interconnected and discrete in nature. Cellular automata are well-known methods to predict network traffics in cellular spaces. Therefore, to predict cancer pathways involved, we propose a 2-dimensional cellular automata approach

Using a novel methodological approach to measure emotions in Facebook comments, this Work in Progress (WIP) paper explores the relationship between negative feelings and ideological cross-posting behavior. Using the VoxPopuli data harvester, we collect over 770,000 public Facebook comments1 from the three major political campaign pages active during the Brexit referendum. After sorting users into

BACKGROUND: Preschool children with autism in southern Sweden participated in a comprehensive Naturalistic Developmental Behavioral Intervention (NDBI) program. AIMS: To evaluate the ongoing NDBI program by comparing the pre- and postintervention outcomes in terms of improved autism symptom severity. METHOD: The improvement of Autism Diagnostic Observation Schedule (ADOS-R) test results between ba

hCAP-18 is a newly described protein of human neutrophilic granulocytes which belongs to the cathelicidin family of antimicrobial proteins. Members of this protein family share a common N-terminal sequence followed by a highly diverse antimicrobial, cationic C-terminus. The present work describes the production of recombinant hCAP-18, the generation of antibodies to the protein and the development

Today, many control applications in cyber-physical systems are implemented on shared platforms. Such resource sharing may lead to complex timing behaviors and, in turn, instability of control applications. This paper highlights a number of anomalies demonstrating complex timing behaviors caused as a result of resource sharing. Such anomalous scenarios, then, lead to a dramatic increase in design c

Binary star systems are assumed to be co-natal and coeval, and thus to have identical chemical composition. In this work, we aim to test the hypothesis that there is a connection between observed element abundance patterns and the formation of planets using binary stars. Moreover, we also want to test how atomic diffusion might influence the observed abundance patterns. We conduct a strictly line-

Active vitamin D, 1,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)], plays a pivotal role in calcium homeostasis and bone metabolism. Circulating levels of 1,25(OH)(2)D(3) are thought to be dependent mainly on the activity of the renal cytochrome P450 enzyme 25-hydroxyvitamin D(3)-1alpha-hydroxylase (1alpha-hydroxylase), which is potently induced by PTH. However, 1alpha-hydroxylase activity or expressi

The drug FK506 (tacrolimus, fujimycin) exerts its immunosuppressive effects by regulating the nuclear factor of the activated T-cell (NFAT) family of transcription factors. However, FK506 also exhibits neuroprotective effects, but its direct target proteins that mediate these effects have not been determined. To identify the target proteins responsible for FK506's neuroprotective effects, the drug

Histopathologic classification of cancer in the lung is important for choice of treatment. Cytokeratin 5 (CK5), p63, and p40 are commonly used immunohistochemical markers for squamous cell carcinoma, and napsin A (NAPA) and thyroid transcription factor 1 (TTF-1) are markers for adenocarcinoma of the lung. The aim of the present study was to evaluate these 5 markers and to compare different commerc

The aim of the TEDDY study is to identify infectious agents, dietary factors, or other environmental agents, including psychosocial factors, which may either trigger islet autoimmunity, type 1 diabetes mellitus (T1DM), or both. The study has two end points: (a) appearance of islet autoantibodies and (b) clinical diagnosis of T1DM. Six clinical centers screen newborns for high-risk HLA genotypes. A

Rysk-amerikanska Emma Goldman och kinesiska He-Yin Zhen kom från två olika delar av världen och var aktiva inom olika kunskapstraditioner och kulturer. Ändå var de båda anarkister som kämpade för kvinnlig frigörelse, och båda var de kritiska till de samtida rörelserna som stred för kvinnors politiska rättigheter. Det finns få studier som jämför tidig amerikansk feminism med tidig kinesisk feminismRussian-American Emma Goldman and Chinese He-Yin Zhen came from different parts of the world, and thus weren’t active within the same knowledge systems and cultures. However, they were both anarchists fighting for the liberation of women, and both were strongly criticising the contemporary women’s suffrage movements. Few comparisons have been made between early Chinese feminism and early American

Utveckling av en metod för att kartera högsta kustlinjen i Sverige med hjälp av brytlinjer extraherade från högupplösta höjdmodeller Högsta kustlinjens (HK) geografiska läge i landskapet markerar gränsen mellan subakvatiskt och supraakvatiskt avsatta sediment. Idag varierar HKs höjd över havet från några få m.ö.h. i Skåne till omkring 289 m.ö.h. i Ångermanland på grund av den glacialisostatiska lDevelopment of a method for mapping the highest coastline in Sweden using breaklines extracted from high resolution digital elevation models The geospatial position of the highest coastline (HCL) defines the boundary between subaquatic and supra-aquatic deposited sediments. Today the HCL is located at different elevations throughout Sweden, a few m.a.s.l. in southern Scania to around 289 m.a.s.l.

Based on the Synchrotron Radiation (SR) beamline optical element-by-element alignment with analysis of the alignment results an optimized beamline alignment algorithm has been designed and developed. The alignment procedures have been designed and developed for the MAX-lab 1911-4 fixed energy beamline. It has been shown that the intermediate information received during the monochromator alignment