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Mounting discoveries of extrasolar planets orbiting post-main-sequence stars motivate studies to understand the fate of these planets. In the traditional 'adiabatic' approximation, a secondary's eccentricity remains constant during stellar mass-loss. Here, we remove this approximation, investigate the full two-body point-mass problem with isotropic mass-loss, and illustrate the resulting dynamical

Human neutrophil peptide-1 (HNP-1) is a member of the alpha-defensin family. Defensins are cationic antimicrobial peptides, which play an important role in the antimicrobial response to microorganisms. In addition, recent studies have revealed the involvement of defensins in inflammation, immunity and wound repair. Defensins are present in the azurophilic granules of neutrophils and are released u

Knockout of caspase-8, a cysteine protease that participates in the signaling for cell death by receptors of the TNF/nerve growth factor family, is lethal to mice in utero. To explore tissue-specific roles of this enzyme, we established its conditional knockout using the Cre/loxP recombination system. Consistent with its role in cell death induction, deletion of caspase-8 in hepatocytes protected

Platelet activating factor (PAF) has been reported to produce a variety of airway effects including epithelial damage and increased airway-lung absorption of hydrophilic tracers. The present study examines effects of PAF on the guinea-pig tracheobronchial mucosa in vivo. Vehicle with and without PAF (4.0 and 8.0 nmol) was superfused onto the tracheobronchial mucosa. The levels of 125I-albumin, pre

After infection with Borrelia burgdorferi, humans and mice under certain conditions develop arthritis. Initiation of inflammation is dependent on the migration of innate immune cells to the site of infection, controlled by interactions of a variety of adhesion molecules. In this study, we used the newly synthesized compound S18407, which is a prodrug of the active drug S16197, to analyze the funct

Popular Abstract in Swedish Detta är en avhandling om hur en del av vårt meningsskapande går till, sedd genom åtta studenters användning av sina kontextuella resurser. Den handlar om hur vi lyssnar till auditiva, visuella och upplevda röster, och hur vi talar med stöd av dessa röster när vi skapar och utvecklar vår egen röst. Detta kallar jag för rapporterat lyssnande, d.v.s. dessa yttranden visarThis thesis has two points of departure and four main purposes. The first point of departure concerns the narrow perspective of the listening skill in Swedish. The first purpose is to show the lack of attention to the listening skill in research and mother tongue education in the Swedish compulsory school. Educational documents from 1842 to 2000 about Swedish as a school subject are examined from

The ERP market has been changing since the implementation peaks observed around Y2K, when most of the high-end adopters take their chance of substituting legacy systems while implementing integrated management. This adoption movement from bigger companies created a reaction on the Small and Medium-sized Enterprises (SMEs) ERP market: on the vendor side, it was necessary to find new market segments

The Official records of the Swedish Foreign Ministry and War Ministry clearly indicate that the Stockholm was fully aware of the ongoing massacres and deportations of the Armenian subjects in the Ottoman Empire in an intentional annihilation of the Armenian nation.

The paper is based on a general conceptual supply chain flow risk model developed in an earlier paper, a literature review and case studies. The paper has the title "Developing a supply chain risk model" and is reported as a final paper at the NOFOMA 2005 conference. The literature review has been focusing articles and reports/books on supply chain management. Some of its findings have earlier bee

Many studies focusing on design activities use the interview technique as part of their investigation. Nevertheless, methodological discussions about the interview setting as the locus of a social interaction between the interviewer and the respondent and its implications for the interpretation of the data obtained are rarely found in publications within our design community. Part I of this public

In sociology, new institutionalists led the revival in interest in institutions in organizational theory and economic sociology by shifting the focus of causal reasoning from agent-centric studies of economic and organizational actors to the relationship connecting the firm with its institutional environment. We suggest a multilevel causal model incorporating the connection between the subinstitut

A new generalized bimodal traffic stream model deriving theoretically (i.e., via some underlying model of driver behavior) from (local) equilibrium solutions of a kinetic equation of vehicular traffic is presented and shown to have the correct flow behavior at jam density. This bimodal traffic stream model depends not only on parameters such as the desired speed w, the headway σ(0) at jam density

In this thesis aspects of peripheral B lymphocyte differentiation were studied. Through in vitro experiments, B lymphocyte activation was assessed. B lymphocytes express immunoglobulin (Ig) specific for a certain antigen on the cell surface, and when surface Ig is crosslinked by an antigen, the cell is activated. Antigens giving rise to a T cell dependent immune response are internalized by the B

Most methods that guide the designer through the later phases of the design process are general in nature, and it is up to the designer to organize the design work using the tools and techniques available. This process also relies greatly on experience, which is quite a challenge for students, who are mostly novices in the area. In a comparative study, the evolution of the experience and skills ac

Many studies focusing on the design activity use the interview technique as a part of their investigation. Methodological discussions about the interview setting as the locus of a social interaction between the interviewer and the respondent and its implications for the interpretation of the obtained data are nevertheless rarely found in publications within our design community. Part I of this pub

A rapid and simple approach of lactose analysis is proposed based on 3rd generation amperometric biosensors employing cellobiose dehydrogenase (CDH) from Trametes villosa or Phanerochaete sordida immobilised on screen-printed carbon electrodes (SPCEs). After optimisation of the working conditions of the biosensors - pH of the carrier buffer, flow rate and applied potential - the sensors were able

This study explored the role of secreted fibroblast-derived factors in prostate cancer growth. Analyses of matched normal and tumor tissue revealed up-regulation of CXCL14 in cancer-associated fibroblasts of a majority of prostate cancer. Fibroblasts overexpressing CXCL14 promoted the growth of prostate cancer xenografts, and increased tumor angiogenesis and macrophage infiltration. Mechanistic st