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In vision-based feedback control systems, the time to obtain sensor information is usually non-negligible, and these systems thereby possess fundamentally different timing behavior compared to standard real-time control applications. For many image-based tracking algorithms, however, it is possible to trade-off the computational time versus the accuracy of the produced position/orientation estimat
Immune checkpoint inhibitors (ICI) targeting programmed cell death‐1 or its ligand (PD‐ L1) have improved outcomes in non‐small cell lung cancer (NSCLC). High tumor PD‐L1 expression, detected by immunohistochemistry (IHC) typically on formalin‐fixed paraffin‐embedded (FFPE) histological specimens, is linked to better response. Following our previous investigation on PD‐L1 in cytological samples, t
This paper discusses new improvements of a form-based algorithm, which is used to estimate flow distribution over a continuous surface. In the new form- based algorithm (IFBFD), cells in a DEM are classified into five different classes. The classes are Peaks, Complicated, Sinks, Flats and Undisturbed cells. The method of how to estimate the flow distribution from each cell depends on its class. Es
The current view of type 1 diabetes (T1D) is that it is an immune-mediated disease where lymphocytes infiltrate the pancreatic islets, promote killing of beta cells and cause overt diabetes. Although tissue resident immune cells have been demonstrated in several organs, the composition of lymphocytes in human healthy pancreatic islets have been scarcely studied. Here we aimed to investigate the ph
As tech giants such as Apple and Meta invest heavily in Virtual and Augmented Reality (VR/AR) technologies, often collectively termed Extended Reality (XR) devices, a significant societal concern emerges: The use of eye-tracking technology within these devices. Gaze data holds immense value, revealing insights into user attention, health, and cognitive states. This raises substantial concerns over
This paper is based on the work done for the 2017 AIAA Student Design Competition-Human Spaceflight: Phobos Base. One of humanity's major challenges when travelling to Mars is represented by the existence of an atmosphere around the red planet. In fact, even though the Martian atmospheric density is only about 1% of that of Earth, the entry, descent and landing (EDL) procedure for large payloads i
Popular Abstract in Swedish Bibeln, och framför allt Nya Testamentet, har präglat det västerländska tänkandet i en utsträckning som inte alltid noteras i nyare historieskrivning. En ledande roll har spelats av de uppfattningar av Gud som förmedlas av de fyra evangelierna. Inte minst har läsningar av Johannesevangeliet genomsyrat de kristna tänkarnas försök att formulera synen på Guds väsen, egenskThis book presents an exhaustive and systematic investigation of six representatives of three important periods of New Testament interpretation: Martin Luther, John Calvin, Brooke Foss Westcott, Heinrich Julius Holtzmann, Rudolf Bultmann and Raymond E. Brown. They serve as dialogue partners in an investigation of the notion of God in the Fourth Gospel, a topic that has been called “the neglected f
Background: During wound healing processes fibroblasts account for wound closure by adopting a contractile phenotype. One disease manifestation of COPD is emphysema which is characterized by destruction of alveolar walls and our hypothesis is that fibroblasts in the COPD lungs differentiate into a more contractile phenotype as a response to the deteriorating environment. Methods: Bronchial (centra
The aim of this thesis is to examine the relationship between writing and alterity in three recent novels written by J. M. G. Le Clézio, Désert (1980), Onitsha (1991) and La quarantaine (1995), which deal with the encounter between the so-called primitive cultures and Western society. The first chapter contains a more general discussion on the discourse of alterity in literature and the French exo
When decision on repair has been taken the available repair systems/methods must be evaluated with regard to the immediate requirements. For each type and cause of damage, there are normally only a few possible repair systems. These repair systems should be evaluated with regard to following 5 basic properties, or characteristics: 1) service life/durability, 2) structural stability/safety, 3) exec
Five students of a rescue training school cycled at 50 W for 20 minutes at 20 °C before walking up to 30 minutes in a climatic chamber at 55 °C and 30 % relative humidity. Four different types of clothing ensembles were used differing in terms of thickness and thermal insulation value were tested on separate days. All subjects completed 28-30 minutes in light clothing, but quitted after 20-27 minu
The feasibility of administering metoclopramide (MCA) as a radiosensitizer has been evaluated in 23 patients with a pathological or cytological diagnosis of a squamous cell carcinoma of the lung, clinically evaluated as inoperable. All patients received 40-60 Gy radiotherapy fractionated into 1.8 Gy fractions 5 times per week (Monday-Friday). Two MCA treatment regimens were used: (i) MCA at 2 mg/k
Several transporter systems in the liver and intestine are known to change their expression and function during cholestatic disease states. The objective of the-present in vivo study-was to investigate the effect of biliary depletion, as a method to mimic cholestasis, on the bioavailability and disposition of digoxin in biliary and pancreatic duct cannulated pigs. The study was divided in two part
The 4MOST([1]) instrument is a concept for a wide-field, fibre-fed high multiplex spectroscopic instrument facility on the ESO VISTA telescope designed to perform a massive (initially >25x10(6) spectra in 5 years) combined all-sky public survey. The main science drivers are: Gaia follow up of chemo-dynamical structure of the Milky Way, stellar radial velocities, parameters and abundances, chemical
Importance: Cancer is the second leading cause of death worldwide. Current estimates on the burden of cancer are needed for cancer control planning.Objective: To estimate mortality, incidence, years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life-years (DALYs) for 32 cancers in 195 countries and territories from 1990 to 2015.Evidence Review: Cancer mortality w
As a prototype of genomics-guided precision medicine, individualized thiopurine dosing based on pharmacogenetics is a highly effective way to mitigate hematopoietic toxicity of this class of drugs. Recently, NUDT15 deficiency was identified as a genetic cause of thiopurine toxicity, and NUDT15-informed preemptive dose reduction was quickly adopted in clinical settings. To exhaustively identify pha
Contemporary English as a foreign language (EFL) classrooms in upper secondary schools in Sweden make frequent use of receptive media such as movies and television to facilitate language learning. The more interactive medium of video games is seldom used for the same purpose, despite previous research indicating that the added layer of interactivity can bring benefits such as improvements to vocab
