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Importance: Cancer is the second leading cause of death worldwide. Current estimates on the burden of cancer are needed for cancer control planning.Objective: To estimate mortality, incidence, years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life-years (DALYs) for 32 cancers in 195 countries and territories from 1990 to 2015.Evidence Review: Cancer mortality w

As a prototype of genomics-guided precision medicine, individualized thiopurine dosing based on pharmacogenetics is a highly effective way to mitigate hematopoietic toxicity of this class of drugs. Recently, NUDT15 deficiency was identified as a genetic cause of thiopurine toxicity, and NUDT15-informed preemptive dose reduction was quickly adopted in clinical settings. To exhaustively identify pha

Visual localization enables autonomous vehicles to navigate in their surroundings and augmented reality applications to link virtual to real worlds. Practical visual localization approaches need to be robust to a wide variety of viewing condition, including day-night changes, as well as weather and seasonal variations, while providing highly accurate 6 degree-of-freedom (6DOF) camera pose estimate

Immune checkpoint inhibitors (ICI) targeting programmed cell death‐1 or its ligand (PD‐ L1) have improved outcomes in non‐small cell lung cancer (NSCLC). High tumor PD‐L1 expression, detected by immunohistochemistry (IHC) typically on formalin‐fixed paraffin‐embedded (FFPE) histological specimens, is linked to better response. Following our previous investigation on PD‐L1 in cytological samples, t

This paper discusses new improvements of a form-based algorithm, which is used to estimate flow distribution over a continuous surface. In the new form- based algorithm (IFBFD), cells in a DEM are classified into five different classes. The classes are Peaks, Complicated, Sinks, Flats and Undisturbed cells. The method of how to estimate the flow distribution from each cell depends on its class. Es

This paper is based on the work done for the 2017 AIAA Student Design Competition-Human Spaceflight: Phobos Base. One of humanity's major challenges when travelling to Mars is represented by the existence of an atmosphere around the red planet. In fact, even though the Martian atmospheric density is only about 1% of that of Earth, the entry, descent and landing (EDL) procedure for large payloads i

Amplification of fibroblast growth factor receptor 1 (FGFR1) in non-small cell lung cancer (NSCLC) has been considered as an actionable drug target. However, pan-FGFR tyrosine kinase inhibitors did not demonstrate convincing clinical efficacy in FGFR1-amplified NSCLC patients. This study aimed to characterise the molecular context of FGFR1 expression and to define biomarkers predictive of FGFR1 in

Introduction: During airway infection, upregulation of proinflammatory cytokines and subsequent immune cell recruitment is essential to mitigate bacterial infection. Conversely, during prolonged and non-resolving airway inflammation, neutrophils contribute to tissue damage and remodeling. This occurs during diseases including cystic fibrosis (CF) and COPD where bacterial pathogens, not least Pseud

INTRODUCTION: Immune cells in the tumour microenvironment are associated with prognosis and response to therapy. We aimed to comprehensively characterise the spatial immune phenotypes in the mutational and clinicopathological background of non-small cell lung cancer (NSCLC).METHODS: We established a multiplexed fluorescence imaging pipeline to spatially quantify 13 immune cell subsets in 359 NSCLC

The current view of type 1 diabetes (T1D) is that it is an immune-mediated disease where lymphocytes infiltrate the pancreatic islets, promote killing of beta cells and cause overt diabetes. Although tissue resident immune cells have been demonstrated in several organs, the composition of lymphocytes in human healthy pancreatic islets have been scarcely studied. Here we aimed to investigate the ph

1 3 February 2021 Management Response External Evaluation of the Raoul Wallenberg Institute Turkey Human Rights Capacity Development Programme, 2015-2020 Background In July 2020, the Raoul Wallenberg Institute of Human Rights and Humanitarian Law (RWI) commissioned an external evaluation of its Turkey Human Rights Capacity Development Programme 2015-2020 (the Programme) to assess the effectiveness

https://rwi.lu.se/wp-content/uploads/2022/04/Management-Response-to-Evaluation-final-002.pdf - 2026-05-01

Untitled 1 Ships and Aerospa ce Karl Johan Åström Department of Automatic Control LTH Lund University Ships and Aerospa ce K. J. Åström 1. Introduction 2. Ships 3. Early Autopilots for Aircrafts 4. German Autopilots 5. Missiles 6. Later Developments 7. Summary Theme: Gyroscopes, powerful actuators and mission critical systems. Lectures 1940 1960 2000 1 Introduction 2 Governors | | | 3 Process Cont

https://www.control.lth.se/fileadmin/control/Education/DoctorateProgram/HistoryOfControl/2016/L06ShipsAndAerospaceeight.pdf - 2026-05-01

Contemporary English as a foreign language (EFL) classrooms in upper secondary schools in Sweden make frequent use of receptive media such as movies and television to facilitate language learning. The more interactive medium of video games is seldom used for the same purpose, despite previous research indicating that the added layer of interactivity can bring benefits such as improvements to vocab

Microsoft Word - FU_vid_CEE_eng.docx Address P O Box 124, SE 221 00 Lund, Sweden Street address: John Ericssons väg 3 Telephone , +46 (0)46-222 3626 Email per.warfvinge@rektor.lth.se Web http://www.lth.se Centre for Engineer ing educat ion Framework for Research Education in the subject Engineering education (Pedagogisk utveckling inom teknikvetenskap, TEIDEF05) at the Center for Engineering Educa

https://www.lth.se/fileadmin/cee/Documents/FU_vid_CEE_eng.pdf - 2026-05-01

AbstractBackgroundThe role of nutrient intake in celiac disease pathogenesis is poorly understood.ObjectiveTo examine whether longitudinal childhood intake of selected vitamins and minerals is associated with celiac disease autoimmunity (CDA, primary outcome) and celiac disease (secondary outcome) in genetically at-risk children.MethodsA total of 6,520 HLA-conferred at-risk children in the observa

Target cell entry of HIV-1 is dependent on the binding of gp120, the outer component of the viral envelope glycoprotein complex (Env), to CD4 and a coreceptor, preferentially CCR5 or CXCR4. Still, other interactions may also contribute to the infectivity of the virus. One such interaction is between the highly glycosylated gp120 and carbohydrate-binding proteins, such as galectins. Here, we studie

Publications | Department of Automatic Control Faculty of Engineering, LTH Search Department of Automatic Control LTH, Faculty of Engineering Education Research External Engagement Personnel Publications About, Contact Home  >  Rolf Johansson  >  Publications Denna sida på svenska This page in English Publications List of Publications—Prof. Rolf Johansson   2021 P.-A. Fransson, M. H. Nilsson, S. R

https://www.control.lth.se/personnel-old/rolf-johansson/publications/ - 2026-05-01