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Cell cycle regulation is essential for proper homeostasis of hematopoietic cells. Cdk2 is a major regulator of S phase entry, is activated by mitogenic cytokines, and has been suggested to be involved in antigen-induced apoptosis of T lymphocytes. The role of Cdk2 in hematopoietic cells and apoptosis in vivo has not yet been addressed. To determine whether Cdk2 plays a role in these cells, we perf
There is a wide-spread concern that technical change may spur social conflicts, especially if workers are replaced with machines. To empirically analyze whether job destruction drives protests, we study a historical example of a revolutionary new technology: the adoption of electricity. Focusing on the gradual roll-out of the Swedish electricity grid between 1900 and 1920 enables us to analyze 2,4
The discourse of the Yemeni TV broadcasters has been undergoing major changes since the Arab Spring in 2011. However, after the recent civil war, specifically since 2015, this discourse has been diverse, and has become a clear reflection of the contexts in which it is produced. This paper attempts to analyze the Yemeni media discourse by analyzing the titles of the news reports published on YouT
Opsin-like immunoreactivity was observed in the retinae and pineal organs of the mouse, rat and guinea pig, and the pineal organ of the cat. In the retina the immunoreaction was restricted to photoreceptor cells, which displayed immunostaining in their perikarya and outer and inner segments. Distinct pinealocytes endowed with characteristic processes were labelled in the pineal organs of the mouse
Ants are some of the most abundant and familiar animals on Earth, and they play vital roles in most terrestrial ecosystems. Although all ants are eusocial, and display a variety of complex and fascinating behaviors, few genomic resources exist for them. Here, we report the draft genome sequence of a particularly widespread and well-studied species, the invasive Argentine ant (Linepithema humile),
Hosting a cultural history of 8.000 years in China, jade has seen a revival in China’s current era. Jadeite is the most expensive type of jade, and the vast majority of jadeite is mined in Myanmar’s Kachin State and sold in China.Spectral Jade is a study of trade, carving, and use of jadeite. The dissertation is based on ethnographic research in different nodes of the jadeite commodity chain, incl
Most of us are fed up of the incessant media coverage of fake news and dishonest political campaigns.We might be fed-up. But at the same time we can’t help but repeatedly mumble our common-sense complaints about a world we don’t recognise: ‘How can even apparently intelligent people believe in fake news about the major issues of this election? Brexit, anti-scientific claims dismissing climate chan
Ganglioside lipids have been associated with several physiological processes, including cell signaling. They have also been associated with amyloid aggregation in Parkinson’s and Alzheimer’s disease. In biological systems, gangliosides are present in a mix with other lipid species, and the structure and properties of these mixtures strongly depend on the proportions of the different components. He
Blood group antigens may be used as receptors by pathogens when infecting their hosts. Different blood groups therefore can be disease susceptibility factors. Thus, pathogens may have exerted a selection pressure on the evolution of blood group diversity. One aim of our study was to identify red blood cell (RBC) membrane structures that are bound by the common human pathogen. Streptococcus pyogene
In this paper, we describe Docforia, a multilayer document model and application programming interface (API) to store formatting, lexical, syntactic, and semantic annotations on Wikipedia and other kinds of text and visualize them. While Wikipedia has become a major NLP resource, its scale and heterogeneity makes it relatively difficult to do experimentations on the whole corpus. These experimentat
Adaptation to temperature regimes and host presence may enhance fitness in parasites. In an experimental study, we evaluated the timing of glochidia release by Unio crassus subjected to three spring water temperature regimes in the presence and absence of the host fish Cottus gobio. The timing of glochidia release was delayed at (i) constantly low temperatures (<10°C), in contrast to earlier and p
This article builds on recent works on witnessing, socially engaged documentary filmmaking and studies on the role of new digital technologies for witnessing trauma, recording memories and enabling activism. In a devastating earthquake in Sichuan province on 12 May 2008, almost 90,000 people, at least 5000 of them being children, died. Parents and bystanders provided the first footage of the earth
The Swedish CArdioPulmonary bioImage Study (SCAPIS) combines the use of new imaging technologies, large-scale proteomics/metabolomics/genomics, and epidemiological analyses to extensively characterize a Swedish cohort of 30,000 men and women aged between 50 and 64 years. Its main aims are to improve risk prediction and to optimize our ability to study mechanisms of cardiopulmonary diseases. SCAPIS
This paper examines two failed land acquisition processes for food and biofuels production in Africa with the aim to establishing more equitable governance strategies. More specifically it explores the roles of certification schemes and codes-of-conduct can play in these processes. The two cases used are the South Korean Daewoo Logistics case in Madagascar and the Swedish SEKAB in Tanzania. The me
We investigated whether dementia risk factors were associated with prodromal Alzheimer's disease (AD) according to the International Working Group-2 and National Institute of Aging-Alzheimer's Association criteria, and with cognitive decline. A total of 1394 subjects with mild cognitive impairment from 14 different studies were classified according to these research criteria, based on cognitive pe
