Filtyp
The purpose of the study is to quantitatively verify the systematic property of default risk and to statistically test if adding a default risk factor to the Fama and French Three-Factor Model can enhance its performance. The applied method is derived from the Fama and French Three- factor methodology and enhancing it with an additional default risk factor. The study employs Credit-Default Swap sp
Tillgången till rent dricksvatten varierar mellan olika delar i världen. Till exempel är grundvat- ten en stor resurs i Sverige där det står för 50 % av dricksvattnet, både artificiellt och naturligt bildat. Den siffran är endast 6 % i Moçambique och med tanke på att 47 % av populationen i landet saknar rent dricksvatten kan artifici- ell grundvattenbildning vara ett bra alternativ. Det finns olikThe amount of clean drinking water varies across different parts of the world. For example is groundwa- ter a big resource in Sweden and stands for 50% of the drinking water, both artificially and naturally recharged. The corresponding fraction is only about 6% in Mozambique and considering that 47% of the population in Mozam- bique lacks clean drinking water artificial recharge might be a good op
Every single State has its own rules: legal persons are created based on the domestic laws and States tax them according to their own tax laws. Thus, differences and imperfect legal relationships are inevitable at the international level. The existence of legal entities formed under diverse domestic laws which are not similar to each other leads to disparities and thus, to difficulties to have a c
Diamond Blackfan Anemia (DBA) is a congenital bone marrow failure syndrome associated with ribosomal gene mutations that lead to ribosomal insufficiency. DBA is characterized by anemia, congenital anomalies, and cancer predisposition. Treatment for DBA is associated with significant morbidity. Here, we report the identification of Nemo-like kinase (NLK) as a potential target for DBA therapy. To id
Alpha-particle irradiation of cells damages not only the irradiated cells but also nontargeted bystander cells. It has been proposed that the bystander effect is caused by oxidants and free radicals generated by the radiation. Recent studies have shown that α(1)-microglobulin protects against cell damage caused by oxidants and free radicals. Using a novel experimental system that allows irradiatio
In nature, the same biochemical reaction can be catalyzed by enzymes having fundamentally different folds, reaction mechanisms and origins. For example, the third step of the reductive catabolism of pyrimidines, the conversion of N-carbamyl-beta-alanine to beta-alanine, is catalyzed by two beta-alanine synthase (beta ASase, EC 3.5.1.6) subfamilies. We show that the "prototype" eukaryote beta ASase
The growing complexity of urban energy systems, climate uncertainties, and geopolitical disruptions highlight the need for energy flexibility and smart management. Recent developments in smart buildings enable real-time adaptability and collective energy behavior through the deployment of Reinforcement Learning (RL), which optimizes energy use, integrates distributed resources, and enhances demand
This thesis explores if, and how, what is written in the newspaper can be used to forecast macroeconomic variables such as inflation, unemployment and consumption. A large data set consisting of articles from the largest Swedish business newspaper is transformed using different methods from the Natural Language Processing field. The focus lies on topic modelling by Latent Dirichlet Allocation as w
Title: Home is wherever your private equity firm takes you - A quantitative analysis comparing cross-border and domestic* transaction multiples in PE acquisitions of Nordic companies Seminar date: 30 May 2024 Course: NEKN02, Master Essay – Finance Programme, 15 ECTS Authors: Clarissa Nowak, Sofia Sjöholm Advisor: Jens Forssbaeck Keywords: Private Equity, Buyouts, Cross-Border, Valuation, Nord
In the dual pursuit of expanding non-fossil fuel electricity capacity and becoming a ‘developed’ nation, India’s development trajectory drives the rapid expansion of large-scale solar photovoltaics (PV). In Jaisalmer, however, this expansion encounters complex socio-ecological landscapes marked by questions of (in)justice and uneven development. Drawing on energy geographies and energy justice, th
SARS-CoV-2 spike (S) protein is crucial for virus invasion in COVID-19. Here, we showed that lipopolysaccharide (LPS) can trigger S protein aggregation at high doses of LPS and S protein. We demonstrated the formation of S protein aggregates by microscopy analyses, aggregation and gel shift assays. LPS at high levels boosts the formation of S protein aggregates as detected by amytracker and thiofl
Background and Purpose: Clonal hematopoiesis of indeterminate potential (CHIP) is a novel age-related risk factor for cardiovascular disease-related morbidity and mortality. The association of CHIP with risk of incident ischemic stroke was reported previously in an exploratory analysis including a small number of incident stroke cases without replication and lack of stroke subphenotyping. The purp
HIP 41378 d is a long-period planet that has only been observed to transit twice, three years apart, with K2. According to stability considerations and a partial detection of the Rossiter- McLaughlin effect, Pd = 278.36 d has been determined to be the most likely orbital period. We targeted HIP 41378 d with CHEOPS at the predicted transit timing based on Pd = 278.36 d, but the observations show no
Authoritarian management and dysfunctional practices and processes have long been seen as the underlying systemic causes of silence within organizations. Individual responses to these causes, rooted in fear and futility, have been the accompanying explanations. While both types of factors contribute to a climate of silence, their dominance in certain contexts—such as consultative meetings among hi
Introduction: The BIN1 rs744373 single nucleotide polymorphism (SNP) is a key genetic risk locus for Alzheimer's disease (AD) associated with tau pathology. Because tau typically accumulates in response to amyloid beta (Aβ), we tested whether BIN1 rs744373 accelerates Aβ-related tau accumulation. Methods: We included two samples (Alzheimer's Disease Neuroimaging Initiative [ADNI], n = 153; Biomark
Life is about timing.-Carl LewisThe understanding of autoimmune type 1 diabetes is increasing, and examining etiology separate from pathogenesis has become crucial. The components to explain type 1 diabetes development have been known for some time. The strong association with HLA has been researched for nearly 50 years. Genome-wide association studies added another 60+ non-HLA genetic factors wit
