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In this study, several biodegradable Mg alloys (Mg5Zn, Mg5Zn0.3Ca, Mg5Zn0.15Ca, and Mg5Zn0.15Ca0.15Zr, numbers in wt%) were investigated after thermomechanical processing via high-pressure torsion (HPT) at elevated temperature as well as after additional heat treatments. Indirect and direct analyses of microstructure revealed that the significant strength increases arise not only from dislocations

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Research demonstrates that highly self-critical individuals can respond negatively to the initial introduction of a range of therapeutic interventions. Yet touch as a form of therapeutic intervention in self-critical individuals has received limited prior investigation, despite documentation of its beneficial effects for well-being. Using the Forms of Self-Criticism/Self-Reassuring Scale, 15 high-

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Mechanobiology plays an important role in tendon healing. However, the relationship between mechanical loading and spatial and temporal evolution of tendon properties during healing is not well understood. This study builds on a recently presented mechanoregulatory computational framework that couples mechanobiological tendon healing to tissue production and collagen orientation. In this study, we

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Background: Previous studies have demonstrated a high prevalence of biochemical vitamin B12 deficiency in infants in Norway. Increased total homocysteine (tHcy) is the most important marker of B12 deficiency in infants. There is a need to evaluate its clinical relevance. Aims: To investigate the prevalence of hyperhomocysteinemia (S-tHcy > 8 μmol/L) suggestive of suboptimal B12 status and the prev

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Biodegradable magnesium (Mg) alloys can revolutionize osteosynthesis, because they have mechanical properties similar to those of the bone, and degrade over time, avoiding the need of removal surgery. However, they are not yet routinely applied because their degradation behavior is not fully understood. In this study we have investigated and quantified the degradation and osseointegration behavior

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Belief in astrology is on the rise, although the reasons behind this are unclear. We tested whether individual personality traits could predict such epistemically unfounded beliefs. Data was collected for 264 participants through an anonymous online survey shared on social media. The survey consisted of four instruments: Belief in Astrology (BAI), the Big Five personality traits (IPIP-30), narciss

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While lake systems in temperate regions have been extensively studied, tropical and subtropical systems have received less attention. Here, we describe the water chemistry and biota of ten inland blue holes on Andros Island, The Bahamas, representative of the morphological, abiotic, and biotic variation among Androsian inland blue holes. The majority of the studied blue holes were vertically strat

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Studies on the mechanical behaviour of rocks, including volcanic rocks, usually seek for unaltered and simple material: rocks without macroscopic defects. However, volcanic rocks are often naturally altered due to the circulation of hydrothermal fluids. This alteration may influence mechanical and physical properties. Here, we study the effect of hydrothermal alteration on the elasticity and failu

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The results of the project SSM2019-5225, “Marine 14C levels around the Swedish coast”, financed by the Swedish Radiation Safety Authority (SSM), are presented in the paper “Spatial and temporal variations of 14C in Fucus spp. in Swedish coastal waters” published in the Journal of Environmental Radioactivity. The project SSM2019-5225 focussed on spatial variations in 14C in Fucus spp. samples colle

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The objective of this study was to evaluate the influence of operational conditions and wastewater properties on the removal of pharmaceuticals, contrast media and antibiotics through ozonation, in order to facilitate the optimization of treatment and its implementation on a full scale. Pilot-scale ozone oxidation trials were performed on treated wastewater, before and after post-precipitation, ov

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The Cambrian succession of the Tingskullen drill core from northern Öland comprises Cambrian Series 2 and Miaolingian (Wuliuan Stage) siliciclastic strata. The major portion of the succession is represented by the Miaolingian Borgholm Formation, which, in ascending order, is subdivided into the Mossberga, Bårstad and Äleklinta members. The Äleklinta Member is barren of body fossils, whereas the Mo

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Aim: The Cockcroft-Gault (CG) creatinine-based equation is still used to estimate glomerular filtration rate (eGFR) for drug dosage adjustment. Incorrect eGFR may lead to hazardous over- or underdosing. Methods: In a cross-sectional analysis, CG was validated against measured GFR (mGFR) in 14 804 participants and compared with the Modification-of-Diet-in-Renal-Diseases (MDRD), Chronic-Kidney-Disea

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Agricultural output fluctuated worldwide after the emancipation of slaves. The usual explanation is that former slaveholders now lacked labor. This is not the full story: slaves were not just laborers but capital investments to support production. Using databases covering more than 40 years from Stellenbosch in the British Cape Colony, this study measures changes in output before and after emancip

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Slutsatsen av denna undersökning är att Birger Gregersson has skrivit ett skickligt utformat, något pompöst officium som förmedlar en bild av Birgitta som ett helt och hållet universellt helgon och samtidigt en utsökt prydnad för sitt eget land. Nils Hermansson har å sin sida givit oss en Birgitta som i sitt liv och sin undervisning är en trogen dotter till Jungfru Maria och en kyrkolärare. Nils H

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c-myc protooncogene positively regulates cell proliferation and overexpression of c-myc is found in many solid tumors and leukemias. In the present study we used the K562 human myeloid leukemia cell line as a model to study the functional interaction between c-Myc and p53. Using two different methods, we generated K562 transfectant cell lines with conditional expression of either c-Myc or p53. The

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The human antimicrobial peptide LL-37 permeabilizes the plasma membrane of host cells, but LL-37-induced direct effects on mitochondrial membrane permeability and function has not been reported. Here, we demonstrate that LL-37 is rapidly (within 20 min) internalized by human osteoblast-like MG63 cells, and that the peptide co-localizes with MitoTracker arguing for accumulation in mitochondria. Sub

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This article aims to provide a systemic instrument to evaluate the functioning of higher education systems. Despite systemic instruments have had a strong impact on the management of public policy systems in fields such as health and innovation, higher education has not been widely discussed in applying this type of instrument. Herein lies the main gap that we want to close. The ultimate purpose o

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Background: Medical conditions related to alcohol use disorders (AUD) represent a substantial public health concern. However, only a subset of individuals with AUD develop these conditions and the extent to which genetic and environmental factors that are shared with AUD, versus those distinct from it, contribute to this progression has not yet been determined. Methods: Using data from Swedish nat