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Background: Treatment of common bile duct (CBD) stones after Roux-en-Y gastric bypass (RYGB) poses a particular challenge given the altered anatomy and inability to perform a standard endoscopic retrograde cholangiogram (ERC). The optimal treatment strategy for intraoperatively encountered CBD stones in post-RYGB patients has not been established. Objectives: To compare outcomes following laparosc
The highly variable complementary determining region 3 (CDR3) of antibodies is generated through recombination of immunoglobulin heavy chain variable (IGHV), diversity, and joining genes. The codons encoding the first residues of CDR3 may be derived directly from the IGHV germline gene but they may also be generated as part of the rearrangement process. Data of the nucleotide composition of these
The cytotoxic quinolone CP-115,953 specifically exerts its inhibitory effect upon eukaryotic topoisomerase II. CP-115,953 stimulates DNA cleavage mediated by topoisomerase II with a potency approximately 600 times greater than that of ciprofloxacin, a quinolone antibacterial agent that currently is in clinical use. Because ciprofloxacin has been reported to strongly enhance interleukin-2 productio
Parkinson's disease (PD) is a neurodegenerative disease with unknown etiology. Here we show the generation of an induced pluripotent stem cell (iPSC) line, named CSC-40, from dermal fibroblasts obtained from a 59-year-old male patient with a homozygous p.Q456X mutation in the PTEN-induced putative kinase 1 (PINK/PARK6) gene and a confirmed diagnosis of PD, which could be used to model familial PD.
This paper proposes a theory of gazelle growth in which gazelles can grow either organically or through acquisitions. The model includes three types of firms: incumbent, target, and gazelle. We show that the lower cost of organic growth can increase the incentives for acquisition growth because the incumbent understands that if it acquires the target firm, the gazelle will then invest organically
In aqueous solution of 1,1'-diethyl-2,2'-carbocyanine J-aggregate, the exciton self-trapped (EST) state is usually expected to be negligible. However, in this work, by measuring transient absorption spectroscopy under a variety of excitation fluences, the EST state was found to be formed via coherent exciton-exciton annihilation (EEA), when the excitation fluence was high enough. With the existenc
While all institutions are silent toward the war and crime in yemen, we can see the free journalistic institution can play a positive role to fight against violations.
For Eastern Africa, very little information about the SSH knowledge production can be found from a European perspective. Adequate indicators like information-rich bibliographic databases that cover East-Africa-based journals and book publishers are lacking. This research in progress explores their indexing situation in detail, their development, which is closely connected to political history, the
