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Aging of the hematopoietic stem cell compartment is believed to contribute to the onset of a variety of age-dependent blood cell pathophysiologies. Mechanistic drivers of hematopoietic stem cell (HSC) aging include DNA damage accumulation and induction of tumor suppressor pathways that combine to reduce the regenerative capacity of aged HSCs. Such mechanisms do not however account for the change i
1928 började stadsplaneorgan i Stockholm stad planera åtgärdandet av stadsplaneproblem på Nedre Norrmalm. I diskursen var det aldrig fråga om, utan hur dessa kunde lösas genom stadssanering: omfattande rivningar av stadsdelens befintliga bebyggelse. 1952 inleddes slutligen Norrmalmsregleringen, svensk historias mest omfattande stadsplaneprojekt. I den här studien har saneringsbehoven kartlagts i e
The aim of the thesis is to explore the relevance and the values related to physical books for students in the library room. The thesis addresses questions of how students use the physical books in the library room and if the physical books are perceived by the students as a source of formal and informal learning and serendipity. It will also try to find out what impact physical books have on stud
The aim of this study was to examine support given to adult female victims of human trafficking for sexual purposes, by interviewing Swedish professionals within the organisation field. The focus was on how the support given in Sweden is adjusted to meet the women’s needs according to the professionals. We also examined the follow-up within other countries and their collaboration with Swedish orga
Syftet med denna masteruppsats i praktisk teologi, inriktad mot hymnologi, är att undersöka hur psalmförfattarens liv och omvärld påverkar psalmskrivandet av nutida psalmtexter inom Svenska kyrkan, genom kvalitativa intervjuer med några etablerade psalmförfattare. Urvalskriterier för studien var att psalmförfattaren är representerad i Den svenska psalmboken 1986 eller Psalmer i 2000-talet, kan välThe purpose of this master's thesis in practical theology, with a focus on hymnology, is to investigate how the life and environment of hymn writers influence the composition of contemporary hymn texts within the Church of Sweden. This is achieved through qualitative interviews with established hymn writers. The selection criteria for the study included the hymn writer’s representation in the
Purpose: The purpose of this research paper is to study the promotion of non-profitable products by exploring the greater good initiatives of country branding in terms of brand identity and brand image. Design/methodology/approach: The research paper takes a qualitative approach and combines primary and secondary data. The primary data was collected through an interview. The secondary data is bas
In the 1880s, the Anglo-German feminist freethinker Mathilde Blind wrote a series of poems inspired by her residence in Manchester. Our chapter reads Blind’s Manchester poems through the lens of the atmospheric humanities, focusing on how these poems show the entanglement of the human with both urban and natural environments, gesture towards an imagined future for those marginalized in industrial
Encounters between patients in homecare and nursing students are cultural events where students, in principle, are in unknown territory. This study illuminated how nursing students recount (inter)actions in social relations in Danish homecare settings, illustrated by students with a self-appointed immigrant background. The study consisted of semi-structured interviews with eight nursing students.
A series of experiments are carried out to exam the effect of multiple-contact miscibility on drainage using a rock-on-a-chip. The result shows the distinct behaviors depending on the composition and injection flow rate. The observations are compared with the classical parameter regime diagram for drainage displacement of R. Lenormand et al[1].
Emerging evidence suggests differential effects of therapeutic antibiotics on infant T cell responses to pathogens. In this study, we explored the impact of the treatment of mouse infants with amoxicillin and the human milk-derived antimicrobial HAMLET (human alpha-lactalbumin made lethal to tumor cells) on T cell responses to Streptococcus pneumoniae. Lung cells and splenocytes were isolated fr
Monoclonal antibodies are among the most promising therapeutic agents in modern medicine, yet their formulation into high-concentration solutions for subcutaneous self-administration poses a major challenge. A key obstacle is the marked increase in viscosity often observed under these conditions. To gain deeper insights into this phenomenon, coarse-grained models derived from soft matter physics h
It is now established that native language affects one's perception of the world. However, it is unknown whether this effect is merely driven by conscious, language-based evaluation of the environment or whether it reflects fundamental differences in perceptual processing between individuals speaking different languages. Using brain potentials, we demonstrate that the existence in Greek of 2 color
FINAL SIMP45 190830.pdf SIMP45 GRADUATE SCHOOL, FACULTY OF SOCIAL SCIENCES, LUND UNIVERSITY Introduction to Middle Eastern Studies Version 1.0, August 2019 For an always up-to-date online version, please visit the course site (check regularly for updates) Welcome! SIMP45 Welcome to the Autumn term’s course Introduction to Middle Eastern Studies This is an overview course which examines the polit
https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/final_simp45_190830.pdf - 2026-07-22
Popular Abstract in Swedish Populärvetenskaplig sammanfattning: Det genomgående temat i avhandlingen är hur handeln mellan den Europeiska Unionen (EU) och utvecklingsländer kan öka. Två olika policyalternativ utvärderas: så kallade handelspreferenser samt förenklingar av handelsprocedurer. Handelspreferenser innebär i sin enklaste form att höginkomstländer kräver lägre tullar på importvaror somThe main theme of the thesis is how to increase trade between the European Union (EU) and developing countries. Two available policy options are assessed: trade preferences and trade facilitation. Chapter 1 offers a broad discussion of these policies, and concludes that while trade preferences, which once dominated North-South trade relations, are at a risk of becoming obsolete, trade facilitation
We report the use of multinodal acoustic trapping for high throughput and high capacity capturing of EV's (extracellular vesicles) for quantitative mass spectrometry analysis. The multinode trapping unit was shown to isolate sufficient amount of EV's from dilute biological samples (urine and cell culture supernatant) at flow rates of 500 ul/min within minutes, enabling EV proteome profiling. This
Cells of the exocrine pancreas produce digestive enzymes potentially harmful to the intestinal mucosa. Dopamine has been reported to protect against mucosal injury. In looking for the source of dopamine in the small intestine, we found that the duodenal juice contains high levels of dopamine and that the pancreas itself has a high dopamine [and dihydroxyphenylalanine (dopa)] content that does not
Lanthipeptides are ribosomally synthesized and post-translationally modified polycyclic peptides. Lanthipeptides that have antimicrobial activity are known as lantibiotics. Accordingly, the discovery of novel lantibiotics constitutes a possible solution for the problem of antibiotic resistance. We utilized the publicly available genome sequences and the bioinformatic tools tailored for the detecti
Purpose: Elevated copeptin, a vasopressin marker, is linked to metabolic disease, and obese rats with low-vasopressin concentration had a decreased risk of liver steatosis. We here investigated the association between copeptin and nonalcoholic fatty liver disease (NAFLD) and possible differences in copeptin concentration between ethnicities. Methods: In this cross-sectional study of 361 South Afri
