Filtyp
Environmental governance relies on the translation of socioecological knowledge across disciplines and cultural–political boundaries. Comparatively few studies have, however, examined how such expert knowledge is translated back into the local contexts where projects are implemented. This article explores these processes of translation for the case of forest-based carbon offsetting using a case st
Increasing evidence links intraneuronal β-amyloid (Aβ 42) accumulation with the pathogenesis of Alzheimer's disease (AD). In Aβ precursor protein (APP) mutant transgenic mice and in human AD brain, progressive intraneuronal accumulation of Aβ42 occurs especially in multivesicular bodies (MVBs). We hypothesized that this impairs the MVB sorting pathway. We used the trafficking of the epidermal grow
The human antimicrobial peptide LL-37 is produced by neutrophils and epithelial cells, and the peptide can be detected in plasma as well as saliva. LL-37 is active against both gram-positive and gram-negative bacteria including oral pathogens such as Porphyromonas gingivalis and Streptococcus mutans. Besides its antimicrobial properties, LL-37 modulates the innate immune system, and furthermore, i
Primary central nervous system lymphoma (PCNSL), glioblastoma multiforme (GBM) and metastases may be difficult to differentiate based on conventional imaging alone. The aim of this study was to investigate the value of perfusion weighted imaging (PWI) in differentiating homogeneously enhancing PCNSL from homogeneously enhancing GBM and metastases. Seven consecutive patients presenting with homogen
To overcome the blur when visualizing of the interior of a turbid media by means light-based methods, a technique called Structured Laser Illumination Planar Imaging (SLIPI) is employed. The method is based on a 'light coding' strategy to distinguish between directly and multiply scattered light, allowing the intensity from the latter to be suppressed by post-processing data. In this paper, we exp
Objectives. The purpose of this study was to compare the diagnoses of healed myocardial infarction made from the 12-lead electrocardiogram (ECG) by artificial neural networks and an experienced electrocardiographer. Background. Artificial neural networks have proved of value in pattern recognition tasks. Studies of their utility in ECG interpretation have shown performance exceeding that of conven
Timor-Leste began its independence as one of the poorest nations in the world. Substantial progress has been made thereafter but the challenges for future development are numerous. High population growth and modest growth of GDP means that per capita income is declining and that the extent of poverty is increasing. For this situation to change, income opportunities other than those provided by sub
In this paper an OFDM timing synchronization ASIC is presented. The proposed synchronization unit can be used in any OFDM system. The algorithm is based on the correlation introduced by the cyclic prefix, which is exploited in the time domain where the time offset is estimated. Although the algorithm is too complex to be implemented on today's most powerful standard DSP, a hardware architecture th
Swedish native speakers (NSs) unconsciously use tones realized on word stems to predict upcoming suffixes during speech comprehension. The present response time study investigated whether relatively proficient second language (L2) learners of Swedish have acquired the underlying association between tones and suffixes without explicit instruction, internalizing a feature that is specific to their L
A novel adaptive beamformer employing recursively updated soft constraints for acoustic speech enhancement is proposed. The beamformer operates in a subband structure to allow a time-frequency operation for each channel. Consequently, the processing performed can be viewed as a combined weighted spatial,frequency and temporal filter. The major benefit of the new recursive soft constrained beamformer
We hypothesized that key signaling pathways of glioma genesis might enable the molecular classification of gliomas. Gene coexpression modules around epidermal growth factor receptor (EGFR) (EM, 29 genes) or platelet derived growth factor receptor A (PDGFRA) (PM, 40 genes) in gliomas were identified. Based on EM and PM expression signatures, nonnegative matrix factorization reproducibly clustered 1
IMPORTANCE Standard dosing of chemotherapy based on body surface area results in marked interpatient variation in pharmacokinetics, toxic effects, and efficacy.Whether tailored dosing can improve outcomes is unknown, as is the role of dose-dense adjuvant chemotherapy. OBJECTIVE To determine whether tailored dose-dense adjuvant chemotherapy improves the outcomes of early breast cancer compared with
The purpose of this study was to investigate the incidence, clinical presentation, and prognosis of Actinotignum bacteremia in southern Sweden. Actinotignum isolates in blood cultures were identified retrospectively between 1st January 2012 and 31st March 2016 through searches in the clinical microbiology laboratory database. The population covered by this laboratory is approximately 1.3 million.
The chapter focuses on marketing activities of start-up firms. While this is traditionally understood as analyzing the customer needs and how to bridge that gap, for example, through segmentation and branding activities, this chapter has focused on bridging the gaps between industrial actors in order to build networks. The rationale behind this focus relates to the fact that science- and technolog
