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Popular Abstract in Swedish Gliom är den vanligaste typen av hjärntumörer hos vuxna. Den mikroskopiska klassificeringen av de olika formerna av gliom är subjektiv och i vissa fall t.o.m. felaktig, vilket leder till klinisk oklarhet som kan hindra utvecklingen av terapier som riktas mot speciella egenskaper som kännetecknar speciella typer av gliom. EGFR och PDGFRA är en cellreceptor som har en cenGlioma is the most common type of primary tumor in the adult central nervous system (CNS). However, the current classification of gliomas is highly subjective and even inaccurate in some cases, which leads to clinical confusion and hinders the development of targeted therapies. EGFR and PDGFRA play crucial roles in glia development and glioma pathogenesis. In this thesis we aim to establish a glia

Vanadia was deposited on TiO2, ZrO2, HfO2, Nb2O5, and Ta2O5 supports using impregnation with either an oxalic acid solution of NH4VO3 or a solution of vanadyl acetylacetonate in ethanol. Prepared samples, with a nominal vanadia content in the range 0.5–2 monolayers, were characterized with X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Raman and infrared spectroscopy, and were us

When skin specimens are exposed in vitro to L-dopa and catecholamines these substances accumulate in the Langerhans cells where they can be visualized with the histofluorescence method of Falck and Hillarp. Some methodological aspects are discussed and a preliminary study of Langerhans cells in contact allergy is reported.

Aims: The role of resection remains debated in cases of metastatic gastric carcinoma (mGC). Some mGCs are technically resectable. At the population level, the real-world application of resection for mGC remains largely unclear in most Western countries. This large, population-based international investigation aimed to reveal the resection patterns and trends for mGC and the treatment-associated fa

Pålning är en typ av grundläggning lämplig för att grundlägga broar vid svaga markförhållanden. Att manuellt utforma en pålgrupp är en iterativ, tidskrävande process där snittkrafterna i pålarna måste verifieras för ett stort antal lastfall. Efter installationen kan pålarna dessutom ha nya positioner och kapaciteten måste verifieras igen. I detta projekt utvecklades en mjukvara för att automatiserFor bridges in weak ground conditions, piling is an appropriate type of foundation. To manually arrange the piles in a pile group is an iterative, time consuming process where the section forces in the piles must be verified for a large number of load cases. In addition, after installation, piles may have new positions and the capacity must be re-verified. In this thesis, a software was developed

Oil is very important for today’s society and the transportation sector is almost completely dependent on this material. Unfortunately, it affects the level of greenhouse gases negatively which in turn contribute to global warming. Therefore, it is necessary to reduce greenhouse gas emissions, especially in the sectors that emit the most, as transportation sector. The European Parliament has decid

In this thesis, the short- and long-term event study methodology are applied in order to assess whether M&As, in the pharmaceutical industry, create any abnormal return for the acquirer. The majority of the previous research finds a negative abnormal return but the short-term event study seems to generate slightly positive abnormal returns outside the U.S. There is a limited amount of research

Syftet med denna uppsats är att undersöka hur utbildning behandlas i förhållande till EU:s mervärdesskattelagstiftning. Vidare kommer denna uppsats att analysera rättsfall från EU-domstolen och hur domstolens tolkningar av begreppet utbildning relaterar till principen om neutralitet. Med detta som bakgrund kommer uppsatsen gå vidare och titta på hur Sverige har implementerat reglerna för denna typThe purpose of this thesis is to investigate how educational services is regu-lated for tax purposes under EU Law. Further, this thesis will analyse the case law considering educational services from the CJEU and consider how the Courts interpretation relates to the principle of neutrality. With the reg-ulation and case law as a basis, the thesis will then consider how the regula-tion of education

Det finns flera sätt att begränsa konkurrensen, men det finns bestämmelser i nationell och EU-rätt som spelar in när man gör det. Syftet med denna uppsats är att analysera den rättsliga ramen i svensk nationell rätt kring konkurrens mot en arbetsgivare och undersöka under vilka förutsättningar en anställd får konkurrera mot en arbetsgivare. Uppsatsen kommer också att ta en titt på hur konkurrensklThere are several ways of restricting competition, but there are regulations in national and EU- law which come into play when doing so. The purpose of this essay is to analyse the legal framework in Swedish national law concerning competition against an employer and examine the conditions under which an employee is allowed to compete against an employer. The essay will also take a look at how com

The COVID-19 pandemic has been one of the deadliest health crises in modern history. Increasing production of all relevant medical goods and ensuring their equitable distribution has been argued as a necessity to contain the pandemic, which led to the South African and Indian delegation in the TRIPS Council of the World Trade Organization to propose the implementation of a TRIPS waiver to ensure t

Forest carbon sinks are becoming increasingly important as a climate change mitigation tool. To date, New Zealand is the only country that has fully incorporated forestry into its emission trading framework. This study seeks to understand if and how that has impacted forest management practices and carbon sink enhancement. Furthermore, this study seeks to understand to what extent the practices in

In the contemporary global context, the global focus on reducing environmental impacts in any formats has intensified. This study intends to assess the environmental impacts and life cycle costs associated with the A1-A5 stages (production and construction stages) of the Köping Port project and eight additional proposed scenarios. The Solidification/ Stabilization method along with the in-situ tec

With climate change impacting countries around the world, rural communities in Nepal are among those most affected. As acknowledged by global climate discourses, traditional knowledge plays a vital role in understanding and adapting to climate change. Therefore, the purpose of this research is to explore how community members from Darma and Madi Rural Municipalities in western Nepal experience the

If we know that certain ways of making decisions are associated with real-life success, is this then how we should decide? In this paper the relationship between normative and descriptive theories of decision-making is examined. First, it is shown that the history of the decision sciences ensures that it is impossible to separate descriptive theories from normative ones. Second, recent psychologic

In this paper we present a non-linear demand system for households' joint choice of number of trips and days to spend at a destination. The approach, which facilitates welfare analysis of exogenous policy and price changes, is used empirically to study the effects of an increased CO2 tax. In particular, we focus on the effect of including substitution between households choice of the number of tri