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Increases in temperature related to global warming have important implications for organismal fitness. For ectotherms inhabiting temperate regions, ‘winter warming’ is likely to be a key source of the thermal variation experienced in future years. Studies focusing on the active season predict largely positive responses to warming in the reptiles; however, overlooking potentially deleterious conseq
Pulse transformer size is fundamentally linked to application pulselength, pulse power and pulse rise time. In considering long-pulse high-power applications, it has earlier been demonstrated that the large voltage-time integral associated with long-pulse operation in combination with the severe pulse rise time required to ensure high pulse efficiency strictly limits the number of transformer wind
Objective: Although targeted approaches have become available in second- and third-line settings, platinum-based chemotherapy remains the standard first-line treatment for advanced muscle-invasive bladder cancer (MIBC). Therefore, the prediction of platinum resistance is of utmost clinical importance. Methods: In this study, we established a routine compatible method for the molecular classificati
This paper discusses a Python interface for the recently published Dune-Fem-DG module which provides highly efficient implementations of the discontinuous Galerkin (DG) method for solving a wide range of nonlinear partial differential equations (PDEs). Although the C++ interfaces of Dune-Fem-DG are highly flexible and customizable, a solid knowledge of C++ is necessary to make use of this powerful
Oat (Avena sativa L.) is an important and nutritious cereal crop, and there is a growing need to identify genes that contribute to improved oat varieties. Here we utilize a newly sequenced and annotated oat reference genome to locate and characterize quantitative trait loci (QTLs) affecting agronomic and grain-quality traits in five oat populations. We find strong and significant associations betw
Numerous biological mechanisms contribute to outcome after stroke, including brain injury, inflammation, and repair mechanisms. Clinical genetic studies have the potential to discover biological mechanisms affecting stroke recovery in humans and identify intervention targets. Large sample sizes are needed to detect commonly occurring genetic variations related to stroke brain injury and recovery.
Willingness to pay (WTP) for booster doses of coronavirus disease 2019 (COVID-19) vaccines is an under studied research topic. Therefore, the current study aimed to investigate the WTP for the booster doses of COVID-19 vaccines and its predictors in Indonesia using an online survey distributed all over the provinces of this low-middle-income country. The WTP was evaluated using a basic dichotomous
The upcoming Cherenkov Telescope Array (CTA) ground-based gamma-ray observatory will open up our view of the very high energy Universe, offering an improvement in sensitivity of 5-10 times that of previous experiments. NectarCAM is one of the proposed cameras for the Medium-Sized Telescopes (MST) which have been designed to cover the core energy range of CTA, from 100 GeV to 10 TeV. The final came
Background: Rectal washout (RW) is routinely performed during anterior resection (AR) for rectal cancer to reduce local recurrence (LR), although is sometimes not performed during minimally invasive surgery (MIS) procedures due to technical challenges and time consumption. The aim was to investigate the impact of RW on the oncological outcome after AR for rectal cancer in a registry cohort. Method
We have measured radiative lifetimes for selenium and tellurium resonance levels by using short pulse laser excitation in differentially heated resonance cells. We obtained tau(3S1 Se I) = 2.9(5) ns and tau(3S1 Te I) = 3.1(5) ns, which together with branching ratio values given by Ubelis and Berzinsh yield the absorption oscillator strength f(abs)(Se I, 196.0 nm) = 0.074(16) and f(abs)(Te I, 214.3
A modified Delphi method was used to determine thresholds for Minimum Data Set quality indicators for Icelandic nursing homes. The thresholds were then applied to quality outcomes in Icelandic nursing homes for the year 2009. The thresholds indicate areas of good or poor care and can be used for planning services. Icelandic nursing homes seem to be doing best in incontinence and nutritional care.
Consider a reflected random walk Wn+1 = (W-n +X-n)(+), where X-o, X-1,... are i.i.d. with negative mean and subexponential with common distribution F. It is shown that the probability that the maximum within a regenerative cycle with mean mu exceeds x is approximately mu (F) over bar(x) as x --> infinity, and thereby that max (W-o,..., W-n) has the same asymptotics as max(X-o,...,X-n) as n --> inf
To increase our understanding of the genetic basis of adiposity and its links to cardiometabolic disease risk, we conducted a genome-wide association meta-analysis of body fat percentage (BF%) in up to 100,716 individuals. Twelve loci reached genome-wide significance (P<5 × 10(-8)), of which eight were previously associated with increased overall adiposity (BMI, BF%) and four (in or near COBLL1/GR
This paper presents an innovative research on urban risk reduction and climate change adaptation that combines case studies, grounded theory and systems analysis, which could be used as a template for similar intersectoral and interdisciplinary investigations. Such a ‘case studies–grounded theory–systems analysis approach’ permits a grounded theory to be built from case study data, which is viewed
Given an electronic wave function, generated by the MCHF program (LS format) or the MCHF_CI program (LSJ format), this program computes the hyperfine interaction constants, A(J) and B(J). In strong experimental magnetic fields, the splitting is also affected by the off-diagonal hyperfine constants A(J,J-1), B(J,J-1), and B(J,J-2) and these are computed as well, depending on the input data.
