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The continued increased exposure to chemicals and the increasing prevalence of allergic contact dermatitis makes it important to develop accurate testing methods and strategies to assess chemical sensitizers. The Genomic Allergen Rapid Detection (GARD) assay is an in vitro test method that uses the transcriptional response of a myeloid cell line, MUTZ-3, after exposure to test substances to assess
This study examines crisis management work and crisis preparedness ability among Swedish universities - contributing to fill out the existing research gap within this area. It takes 20 crisis management plans into account, focusing on four more in particular along with the undertaking of semi-structured interviews with four university Vice-Chancellors. Furthermore, a conventional content analy
Prior to the accomplishment of this research, the compatibility of the classic e-servicescape conceptual model in the context Taobao and TMall in China were rarely found among existing e-servicescape literatures due to the standardization taken by both online platforms towards the establishment of individual webshops. Meanwhile, the conceptualization of social factors as social dimension of e-serv
This project was done for the company Beijer Electronics Products AB and the task was given by the hardware development department of the company. The project was about developing a concept proposal for a new generation operator panels. This was done to inspire the product developers at Beijer Electronics with innovative ideas before the actual operator panel development. More in detail the object
The primary aim of this study is to assess the significance of top management commitment in the context of Lean 4.0 implementation within the pharmaceutical manufacturing industry in Ghana. The study seeks to understand and evaluate the overall effectiveness and achievements associated with adopting Lean 4.0. Employing a positivist mindset, the research utilizes an explanatory quantitative researc
In 2005 the Swedish Association of the Pharmaceutical Industry (LIF) initiated a national environmental classification and information system for pharmaceuticals. This investigation reports the results from a survey, conducted among the persons involved in the start-up process. The aim of this study is to generate knowledge contributing to the clarification of the motivations, expectations, and in
We investigated the role of blood components in the adhesion of staphylococci to biological and artificial surfaces under well-defined flow conditions by using the Cone and Plate(let) Analyzer. An enzyme-linked immunosorbent assay-like binding assay with biotinylated bacteria determined the extent of bacterial adhesion to subendothelial extracellular matrix (ECM), polystyrene (PS) and adult bovine
Background-Leukocyte concentration in blood is a classical marker of systemic inflammation. Whether high leukocyte counts are associated with incidence of heart failure (HF) is unknown. This population-based study explored whether the leukocyte concentrations were associated with incidence of hospitalizations due to HF. Methods and results-Leukocyte counts were measured in 16 940 men from the gene
The thermoresponsive copolymer of N-isopropylacrylamide (NIPAM) with 1-vinylimidazole (VI), poly(NIPAM-VI), synthesized by radical polymerization has been used to purify the histidine-tagged green flourescent protein (His-tag GFP) from recombinant E. coli by metal-chelate affinity precipitation. The purified protein was immobilized on the BIAcore sensor chip by carbodiimide coupling. Affinity bind
Objectives: To compare the cost-effectiveness of the treatment of ankylosing spondylitis (AS) with infliximab in the United Kingdom over lifetime estimated from two different clinical trials and adjusted for clinical practice guidelines. Methods: A cost-effectiveness model was developed to incorporate clinical, epidemiological, and economic data and allow extrapolation of trial results and incorpo
Pre-treatment of sisal pulp prior to its anaerobic digestion was investigated using an activated sludge mixed culture under aerobic conditions in batch bioreactors at 37 degrees C. The progression of aerobic pre-treatment of the residue in relation to the activities of some extracellular hydrolytic enzymes in the slurry was monitored. The highest activity of hydrolytic enzymes was obtained at 9 h
PURPOSE. Structures derived from periocular mesenchyme arise by complex interactions between neural crest and mesoderm. Defects in development or function of structures derived from periocular mesenchyme result in debilitating vision loss, including glaucoma. The determination of long-term fates for neural crest and mesoderm in mammals has been inhibited by the lack of suitable marking systems. In
BACKGROUND: The outcome after weaning from postcardiotomy venoarterial extracorporeal membrane oxygenation (VA-ECMO) is poor. In this study, we investigated the prognostic impact of arterial lactate levels at the time of weaning from postcardiotomy VA.METHODS: This analysis included 338 patients from the multicenter PC-ECMO registry with available data on arterial lactate levels at weaning from VA
The human B1 bradykinin receptor is an inducible and constitutively active G protein-coupled receptor that is involved in the inflammatory and pain responses to injury. Here, we investigated the role of B1 receptor homo-oligomerization in cell surface receptor expression. B1 receptors tagged with either the FLAG or hemagglutinin epitope were monitored immunologically and by radio-ligand binding, b
Objective: The aim of this study was to analyze the impact of reproductive factors on breast cancer risk among Swedish women by using nationwide population registers. Methods: A cohort including all Swedish women born between 1920 and 1959 was followed up to 1997 by record linkage to different population-based registers. More than 4 million children were linked to the women in the cohort and 60,32
