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188Re-ZHER2:V2, a promising affibody-based targeting agent against HER2-expressing tumors : preclinical assessment

UNLABELLED: Affibody molecules are small (7 kDa) nonimmunoglobulin scaffold proteins with favorable tumor-targeting properties. Studies concerning the influence of chelators on biodistribution of (99m)Tc-labeled Affibody molecules demonstrated that the variant with a C-terminal glycyl-glycyl-glycyl-cysteine peptide-based chelator (designated ZHER2:V2) has the best biodistribution profile in vivo a

Quantifying the Impact of Different Parameters on Optimal Operation of Multi-Microgrid Systems

The multi-objective optimal power management of multi-microgrid systems is solved in this paper. Minimizing the total cost and emission of the system are considered as the objective functions. The multi-objective particle swarm optimization algorithm is applied on a multi-microgrid system that consists of four microgrids each includes diesel generators, wind turbines, photovoltaic units, battery,

Listening across Borders : Global Considerations for Listening and Public Diplomacy

Listening in public diplomacy is a rather new topic in academic discussions. Early public diplomacy scholarship was dominated, and in large degree continues to be dominated, by a focus on crafting messages and influencing. The more recent focus on relationship management and collaborative public diplomacy allowed for discussions about another role for listening. Yet, as some scholars pointed out,

Network optimization techniques

This chapter is devoted to modeling and optimization techniques applicable to communication network design and planning. The main emphasis is put on the models dealing with optimization of the capacity of network resources and traffic routing that lead to tractable optimization problems. It is a common belief that the right means for such modeling are multicommodity flow networks (MFN). MFN form a

Imagetext and ekphrasis as chances of revival in translation studies

Translation Studies has crossed a tumultuous interval of theorization. But has it passed the linguistic limits instituted by a semiotician like Umberto Eco? Wouldn’t be the time to access more courageously the intersemiotic interregnum with its heterogeneous transfer of signs? As it happens in advertising, concrete poetry, tattoos, and stage or filmed version of famous texts? If we have gradually

Smoothing the lies : The distinctive effects of patent characteristics on examiner and applicant citations

Patent citations added by examiners are often used as indicators of technological impact and knowledge flows, despite various criticisms. In this study we analyze the distribution of examiner patent citations according to patent characteristics in order to show their limitations. According to our findings, the number of applicant citations included is dependent on the science-base of the technolog

Transcriptional profiling and assessment of cell lines as in vitro models for mantle cell lymphoma

Mantle cell lymphoma (MCL) is an aggressive malignancy and new treatment modalities must be established to increase patient survival time. In the search for new therapeutic targets, reliable and well-characterised in vitro models are essential. In this study, we have characterised three MCL cell lines (SP53, Granta 519 and NCEB1) in comparison with primary tumors front MCL, follicular lymphomas (F