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Antipsychotic drugs (APD) are commonly prescribed to people living with dementia (PwD) to manage behavioral and psychological symptoms of dementia (BPSD), despite well-documented safety concerns. International guidelines recommend non-pharmacological interventions as first-line treatment, yet APDs remain widely used. This systematic review and meta-analysis synthesize current evidence on the conse
Background Carotid and coronary atherosclerosis are critical determinants of cardiovascular risk, yet their interrelationship in middle-aged populations is incompletely understood. This study assessed carotid plaque composition, risk-factor associations, coronary disease, and sex differences in a subclinical cohort. Methods Within the Swedish CArdioPulmonary bioImage Study, 533 asymptomatic indivi
Peptide therapeutics offer advantages in specificity and affinity, yet the potential propensity to self-associate and aggregate poses a challenge for the development of stable oral formulations. This master’s thesis evaluates the utility of the fluorescent dye Thioflavin T as a structural probe to monitor the aggregation of glucagon-like peptide-1 receptor agonists, specifically Liraglutide and Se
Urban pluvial flooding threatens transport accessibility, yet the spatial factors such as elevation, vegetation, and road density associated with accessibility loss remain insufficiently understood. This study assessed changes in nearest-facility travel time to hospitals, clinics, schools, supermarkets, and fire stations under a 100-year return period flood scenario in Stockholm, Sweden, for both
Bioenergy is the largest energy source in the Swedish energy system, where it consists mainly of domestic forest-based biomass in the form of residues and by-products. Today, there is a general discussion about the need for changes in national forest management policies and new European Union (EU) directives and regulations for forestry and bioenergy to better fulfil biodiversity and climate targe
Reliable ankle torque measurements are important in rehabilitation, where strength assessments are used to evaluate recovery and guide treatment. Isokinetic dynamometers, such as the Biodex system, are commonly used to provide controlled measurements of joint torque. However, these measurements rely on the ankle being held in a stable and reproducible position. Mechanical play in the ankle-attachm
Protein recovery from fermentation broths remains a challenge in downstream bioprocessing due to the complex composition of fermentation media. This study investigated a cascade microfiltration–ultrafiltration (MF–UF) process for protein clarification and concentration from a whey protein-based model fermentation broth. The work evaluated membrane performance, fouling behavior, cleaning efficiency
The ecological footprint of Denmark has been rising since (and likely even before) 1961, which signifies an unsustainable living by the Danish population. Global footprint reports show Denmark as one of many countries on earth which has exceeded its biocapacity (BC), which means natural resource consumption in Denmark is faster than the land’s regenerative capacity. The residents of Denmark are co
It is well-known that long memory and regime switching in the first moment of a stochastic process are easily confused. But the relation between long memory in the second moment and regime switching in the second moment is less well understood. We perform a simulation study in which we assess the possibility to distinguish the two properties in the case that data with long memory in the second mom
Abstract The long-term aim of this project was to develop synbiotic drinks presenting food supplements with beneficial effects on human health. A synbiotic consists of a combination of probiotic bacteria and one or more prebiotics. For the part of the project that was covered by this Master thesis, a probiotic strain, Lactobacillus plantarum F44 and a prebiotic galactooligosaccharide (GOS) were t
Human development index (HDI) is a summary measure used around the world that indicates whether a country is developed, still developing, or undeveloped. HDI incorporates the main factors of human life such as health, education and income. Deprivation in these areas of human life is measured by calculating human poverty index (HPI). The purpose of this thesis is to find the human development index
This thesis undertakes the Causality study with application to exchange rates for Swedish kronor (SEK) with GB pound (£) and US dollar ($) in the frame work of vector Autoregressive (VAR) model. We present the theory behind the Granger Causality, unit roots and vector auto-regression. The Augmented Dickey-Fuller test for unit roots is performed. Our data consist of three time series of daily forei
This master thesis presents a suggested Renovation Passport for two typical 1960s single-family houses. Following the recently approved Energy Performance of Buildings Directive (EU 2024/1275A), all member states are to implement voluntary Renovation Passports by 2026, which will aid in reaching the 2050 goal of a decarbonized building stock. The aim of Renovation Passports is to provide long-ter
This thesis explores the complex relationship between ethnic identity and social mobility within the Māori communities of Aotearoa New Zealand. Central to this research is the role attributed to education, which is seen as a key element in both supporting the preservation of cultural heritage and fostering socio-economic progress. The research examines the contemporary challenges that Māori encoun
