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Early growth and differentiation of the pancreatic endoderm is regulated by soluble factors from the pancreatic mesenchyme. Previously, we demonstrated that N-cadherin-deficient mice lack a dorsal pancreas, due to a critical role of N-cadherin in dorsal pancreatic mesenchymal cell survival. Here, we show that restoring cardiac and circulatory function in N-cadherin null mice by cardiac-specific ex

This case-control study of tobacco smoking and acute myeloid leukemia (AML), emphasizing specific associations with morphologic and cytogenetic subtypes, comprised smoking histories for 333 cases and 351 controls. Smoking status (ever smokers versus life-long non-smokers) showed no evident effect on AML risk. However, an effect of smoking was indicated at high cumulative smoking doses (pack-years)

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The thin-plate spline (TPS) has been widely used in a number of areas such as image warping, shape analysis and scattered data interpolation. Introduced by Bookstein (IEEE Trans. Pattern Anal. Mach. Intell. 11(6):567–585 1989), it is a natural interpolating function in two dimensions, parameterized by a finite number of landmarks. However, even though the thin-plate spline has a very intuitive int

This study aims to increase the knowledge and understanding regarding the situation for undocumented immigrants in the Scandinavian welfare states, mainly from a Swedish perspective, but the situation in Denmark is also included in the discussion. Sweden and Denmark position themselves at the opposite sides of the spectrum regarding immigration policies within the European Union; Swedish immigrati

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Abstract in UndeterminedThe Base of the Pyramid (BoP) consists of about two-fifths of the world population. This population can be categorized as poor with income of less than 2 dollars per day. It is important to alleviate poverty. One of the promising approaches to tackle the wicked problem of poverty is business development combined with poverty alleviation. In this approach, integrated solutio

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The paper intends to show, (1) that W.N. Hohfeld’s theory of fundamental jural relations is relevant to economic theory, and (2) that Hohfeld’s system can be reconstructed by the concepts of ‘liberty space’ and ‘ability space’, understood as an agent’s Spielraum for action. The first half of the paper is devoted to an exposition of Hohfeld’s system and to the question of its relation to the econom

This chapter illustrates how quantum chemical calculations can be used to elucidate structural and functional aspects of tetrapyrrole cofactors, focusing on porphyrins, cobalamins, coenzyme F430, and chlorophyll. A particular emphasis is put on the biochemical significance of axial ligands, which can tune the function of the tetrapyrroles. With the use of quantum chemical calculations, it is possi

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This Norm focussing article starts exploring the various influence processes that take place in connection with the dawn of a new theme - the environment and then sustainable development - in today's society. The Swedish society has in the early 1990-ies declared that educational institutions, places designed for the intentional influence, shall utilise the new environmental theme in its practice.

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The second order random walk (RW2) model is commonly used for smoothing data and for modelling response functions. It is computationally efficient due to the Markov properties of the joint (intrinsic) Gaussian density. For evenly spaced locations the RW2 model is well established, whereas for irregularly spaced locations there is no well established construction in the literature. By considering t

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