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Neutralization of Interleukin-1β following Diffuse Traumatic Brain Injury in the Mouse Attenuates the Loss of Mature Oligodendrocytes

Traumatic brain injury (TBI) commonly results in injury to the components of the white matter tracts, causing post-injury cognitive deficits. The myelin-producing oligodendrocytes (OLs) are vulnerable to TBI, although may potentially be replaced by proliferating oligodendrocyte progenitor cells (OPCs). The cytokine interleukin-1β (IL-1β) is a key mediator of the complex inflammatory response, and

The Identity of the Deacon in Zimbabwe and Sweden

Rapport från ett seminarium sept. 2014 i Manama i Zimbabwe, om diakonens identitet i Lutherska kyrkan i Zimbabwe och i Sverige, två år efter den första vigningen (ordinationen) av diakoner i Evangelical Lutheran Church in Zombabwe.Report from a seminar i Manama in Zimbabwe September 2014: "The Identity of the Deacon in Zimbabwe and Sweden", two years after the first ordination of deacons in the Evangelical Lutheran Church in Zimbabwe (ELCZ).

Diffraction-limited light collection: Promises and challenges of a 50 m ELT

Programmes driving ELT design are discussed. The nature and evolution of circum-stellar shells and planetary discs are attractive, while the small angular sizes place basic properties, asymmetry and warps, beyond VLT capability. An ELT is neeed to reveal the conversion processes shell - disc - planets, planetary systems, Earth-like planets, habitability and life signatures. Formation and evolution

Investigation of the two-phase flow field of the GTX100 compressor inlet during off-line washing

A modern gas turbine compressor, with its highly aerodynamically loaded blades, is sensitive to changes in profile shape and to surface roughness. Fouling is inevitable, despite highly efficient filtration systems. The remedy to this problem is washing. There are two different approaches, online or off-line washing. The off-line wash is the most effective one, whilst on-line washing only prolongs

The Czechoslovak Iron and Steel Industry: Productive efficiency under state socialism in a comparative perspective

Czechoslovak productive efficiency of the iron and steel sector fluctuated below the energy efficiency frontier. Until early 1970s, the country's iron sector was one of the least efficient ones in our sample. It was, however, during the decades of 1970s and 1980s that efficiency measures were adopted and the energy efficiency of the Czechoslovak iron and steel sector increased significantly to, de

Register studies of cancer in the Southern Health Care Region in Sweden

Popular Abstract in Swedish Södra Regionvårdsnämnden har önskat att få belyst om vi har en rättvis och jämlik cancervård i Södra sjukvårdsregionen. Därför har en populationsbaserad registerstudie med många olika etapper genomförts. Basinformationen har hämtats från Tumörregistret i Södra sjukvårdsregionen. Första diagnosdatum noterades och hemort (kommun, distrikt, län) samt sjukhus definierades eThe overall aim was to study different aspect of health care use and health care costs on a population based level for persons with cancer and their partners, and from an individual level to explore the impact of comorbidities in incidence and survival. In the beginning of the study all persons in the Southern Health Care Region in Sweden diagnosed with colon, rectal, breast, prostate and lung can

Georgia in Transition : Perspectives on the Europeanization of Higher Music Education

Music and Performing Arts is one of the fields Georgia can pride itself on internationally. While the country is in transition as it officially embarks on its long path to the European Union membership, this study explores the process of Europeanization of Higher Music Education in Georgia. Authors analyze how Higher Music Educational Institutions employ European projects for organizational change

Accurate prediction of B-form/A-form DNA conformation propensity from primary sequence : A machine learning and free energy handshake

DNA carries the genetic code of life, with different conformations associated with different biological functions. Predicting the conformation of DNA from its primary sequence, although desirable, is a challenging problem owing to the polymorphic nature of DNA. We have deployed a host of machine learning algorithms, including the popular state-of-the-art LightGBM (a gradient boosting model), for b

A Data-driven Riccati Equation

Certainty equivalence adaptive controllers are analysed using a “data-driven Riccati equation”, corresponding to the model-free Bellman equation used in Q-learning. The equation depends quadratically on data correlation matrices. This makes it possible to derive simple sufficient conditions for stability and robustness to unmodeled dynamics in adaptive systems. The paper is concluded by short rema

The Anatomy of Interprofessional Collaboration Around Recommendations in the Intensive Care Unit: An Exploration After Serious Illness Care Training

Background:Serious illness conversations are an iterative, interprofessional, team-based process that includes recommendations about medical care. Yet, it is not clear how clinicians in different role groups work together in this process.Objectives:We sought to examine how interprofessional clinicians in the medical intensive care unit (MICU) who were trained in the serious illness care program (S

Clinical aspects of impulsive-compulsive behaviors under dopaminergic treatment-A scoping review

ObjectiveDopaminergic medications are commonly prescribed for Parkinson's disease (PD), restless legs syndrome, pituitary and psychotic disorders. Accumulating evidence indicates that dopaminergic treatment triggers impulsive-compulsive behaviors (ICBs), yet systematic synthesis of clinical evidence remains limited.MethodThis scoping review summarizes original research directly clinically relevant

Foraging on the wing for fish while migrating over changing landscapes : traveling behaviors vary with available aquatic habitat for Caspian terns

Background: Birds that forage while covering distance during migration should adjust traveling behaviors as the availability of foraging habitat changes. Particularly, the behavior of those species that depend on bodies of water to find food yet manage to migrate over changing landscapes may be limited by the substantial variation in feeding opportunities along the route. Methods: Using GPS tracki

Knowledge and attitudes to cardiopulmonary resuscitation (CPR) - a cross-sectional population survey in Sweden

Aim of the studyRates of bystander CPR are increasing, yet mortality after out-of-hospital cardiac arrest (OHCA) remains high. The aim of this survey was to explore public knowledge and attitudes to CPR. Our hypotheses were that recent CPR training (< 5 years) would be associated with a high-quality response in a case vignette of OHCA with agonal breathing, and associated with an interest to becom