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Placental pulsatility index : a new, more sensitive parameter for predicting adverse outcome in pregnancies suspected of fetal growth restriction

Introduction: The pulsatility indices of the umbilical and uterine arteries are used as the surrogate measures of utero-placental perfusion. Combining the two might simplify the evaluation of total placental vascular impedance, possibly improve prediction of adverse outcomes, and help identify pregnancies with suspected fetal growth restriction that need more intense surveillance. Material and met

Products, Performance, and Technological Development of Ambulatory Oxygen Therapy Devices : Scoping Review

Background: Ambulatory oxygen therapy is prescribed for patients with chronic lung diseases who experience exertional hypoxemia. However, available devices may not adequately meet user requirements, and their performance characteristics are heterogeneous. Objective: This study aims to identify devices available for delivery of ambulatory oxygen therapy, the technologies that they use to generate o

Is It Possible to Reduce the Number of Today’s Thermoplastics? - An Investigation of the Swedish Plastic Industry

Plastic’s unique properties are vital for a sustainable future, but its excessive global use signifies consumer society’s wastefulness, often found in short-lived products. Plastic development has overlooked recycling needs, resulting in low material recycling due to a wide array of plastic types with varying additives, leading to recycling challenges. Research focused on thermoplastics aims to re

Beyond the Binaries: Studying Religion from the Perspective of LGBTQIA Jews, Christians and Muslims in Sweden

When discussing the relationship between religion and LGBTQIA+ rights in Europe today, the two are often framed by both religious and secular representatives as oppositional forces. While the rights of sexual and gender minorities are frequently described as symbols of progress and modernity within liberal democracies, religious communities and traditions are commonly portrayed as defenders of tra

The ALLAN trial: impact of early home-based palliative care on emergency care and hospitalisation in advanced gastrointestinal cancer patients

Bakgrund: Patienter med avancerad gastrointestinal (GI) cancer har en hög symtombörda, vilket ofta medför behov av akutsjukvård. Integration av tidig, hem-baserad specialiserad palliativ vård (SPV) tillsammans med tumörspecifik behandling kan påverka behov av akut sjukvård.Metoder: Vid initiering av palliativ kemoterapi randomiserades patienter med avancerad GI-cancer till tidig hem-baserad SPV inBackgroundPatients with advanced gastrointestinal (GI) cancer experience a high symptom burden which frequently necessitates emergency care. Integration of early home-based specialised palliative care (SPC) with tumour-specific treatments may impact emergency healthcare use.MethodsAt the initiation of palliative chemotherapy, patients with advanced GI cancer were randomised to early home-based SPC

Tiden har runnit ikapp Sverige : Sju principer för god vattenstyrning och hantering

Vi vill med den här artikeln peka på att Sveriges städer har flera utmaningar kring styrning och hantering av vatten, samt föreslår sju principer för lösningar. Klimatförändringarna och den urbana tillväxten gör att åtgärder behövs nu för att hantera både vattenbrist och översvämning på ett integrerat sätt. Här fokuserar vi på kommunnivå och urbana områden, där vi argumenterar för att det behövs eWe argue in this paper that Swedish urban areas have several urgent challenges when it comes to water governance and we propose seven principles for addressing them. Climate change and urban growth call for swift action to manage both water scarcity and flooding in an integrated way. This paper focuses on the municipal level for which we argue that there is a need for a more systematic approach. T

The effect of graded exercise therapy on fatigue in people with serious respiratory illness : a systematic review

Background In adults with serious respiratory illness, fatigue is prevalent and under-recognised, with few treatment options. The aim of this review was to assess the impact of graded exercise therapy (GET) on fatigue in adults with serious respiratory illness. Methods Electronic databases were searched to identify randomised controlled trials (RCTs) testing GET (involving incremental increases in

Advancing personalised care in atrial fibrillation and stroke : The potential impact of AI from prevention to rehabilitation

Atrial fibrillation (AF) is a complex condition caused by various underlying pathophysiological disorders and is the most common heart arrhythmia worldwide, affecting 2 % of the European population. This prevalence increases with age, imposing significant financial, economic, and human burdens. In Europe, stroke is the second leading cause of death and the primary cause of disability, with numbers

The GNAS1 T393C polymorphism and lack of clinical prognostic value in chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) is a clinically heterogeneous disease with no known single predisposing genetic factor shown in all cases. Recently, a single nucleotide polymorphism (SNP) T393C in the GNAS1 gene has been reported to have a clinical impact on CLL progression and overall survival. In order to further investigate the T393C SNP in CLL, we have genotyped 279 CLL cases and correlated

Diagnostics and treatment of human malignant tumours using laser based techniques

Laser-induced fluorescence is a technique for optical tissue characterisation. It has a real-time capability and as the excitation light and the fluorescence emission are transmitted through optical fibres the technique is compatible to various kinds of endoscopes for hollow organ investigation. The tissue fluorescence itself with the emission from the endogenous chromophores or enhanced with exog

Fuzzy inference system for analog joystick emulation with an inductive tongue-computer interface

This paper describes the development of a fuzzy inference system (FIS) for emulating an analog joystick using an inductive tongue-computer interface. The principle of operation of the interface and the inductive sensors signals are described. The FIS receives sensor signals and output the Cartesian position of the virtual joystick, which can be used to control the mouse pointer in a personal compu

The importance for strategic management decision making of understanding the impact of culture on implicit professional values.

The main concern of this paper is the joint utilization of new methods of research and analysis in the study of value. 40 persons, varying from age 20 to 70 and from different professional domains were studies by the use of a three-images technique inspired by Murray´s TAT. The aim was to unveil the implicit dimensions of work related values. Three analytical methods (content analysis, lexical ana

Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor.

MicroRNAs (miRNAs) have been implicated in regulating multiple processes during brain development in various species. However, the function of miRNAs in human brain development remains largely unexplored. Here, we provide a comprehensive analysis of miRNA expression of regionalized neural progenitor cells derived from human embryonic stem cells and human foetal brain. We found miR-92b-3p and miR-1

TP53 Mutations are infrequent in newly diagnosed chronic lymphocytic leukemia

TP53 mutations in the absence of 17p-deletion correlate with rapid disease progression and poor survival in chronic lymphocytic leukemia (CLL). Herein, we determined the TP53 mutation frequency in 268 newly diagnosed CLL patients from a population-based material. Overall, we detected TP53 mutations in 3.7% of patients (n = 10), where 7/10 cases showed a concomitant 17p-deletion, confirming the hig

Minimal Solvers for Unsynchronized TDOA Sensor Network Calibration

Calibration of network nodes using only time differences of arrival (TDOA) measurements opens up for interesting applications in wireless ad-hoc sensor networks, e.g. finding the positions of cell phones by only ambient sounds or radio. We present two novel approaches for the problem of self-calibration of network nodes using only TDOA when both receivers and transmitters are unsynchronized. We co