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In this study, the production of enantiomerically pure (1R,4S,6S)-6-hydroxy-bicyclo[2.2.2]octane-2-one ((-)-2) through stereoselective bioreduction was used as a model reaction for the comparison of engineered Saccharomyces cerevisiae and engineered Escherichia coli as biocatalysts. For both microorganisms, over-expression of the gene encoding the NADPH-dependent aldo-keto reductase YPR1 resulted
The high false negative rates for initial prostate biopsies refer a large number of the men for repeat biopsies each year. Therefore, biomarkers associated with high risk of the presence of malignancy in histologically benign biopsies could provide a tool to discriminate the patients who need repeat biopsy or intensive follow-up from those who do not. Here we examined the diagnostic applicability
Acute management of traumatic brain injury (TBI), in particular mild TBI, focuses on the detection of the 5-7 % who may be harboring potentially life-threatening intracranial hemorrhage (IH) using CT scanning. Guidelines intending to reduce unnecessary head CT scans using available clinical variables to detect those at high IH risk have shown varying results. Recently, the Scandinavian Neurotrauma
Background: Vietnam has achieved considerable success in economic development, poverty reduction, and health over a relatively short period of time. However, there is concern that inequalities in health outcomes and intervention coverage are widening. This study explores if inequalities in reproductive, maternal, newborn and child health and nutrition changed over time in Vietnam in 1997-2006, and
Background: The expected reduction in cervical cancer incidence as a result of increased access to antiretroviral therapy is yet to be seen. In this study we investigated the effect of HIV infection and treatment on high-risk (hr) human papilloma virus (HPV) prevalence and distribution. Methods: Cervical cells from 515 (220 HIV positive and 295 HIV negative) women, recruited during community cervi
Lead in blood is a major concept in biomonitoring of exposure but investigations of its alternatives are scarce. The aim of the study was to describe different lead biomarkers' variances, day-to-day and between individuals, estimating their fraction of the total variance. Repeated sampling of whole blood, plasma and urine were conducted for 48 lead-exposed men and 20 individuals under normal envir
We present evidence for mixed molecular and dissociative water adsorption at monolayer coverage on a rutile TiO2(110) surface free from oxygen vacancies using synchrotron radiation photoemission. At monolayer coverage the OH:H2O ratio is close to 0.5 and reducing the coverage by heating yields an increased OH:H2O ratio. At room temperature neither species originating from the monolayer on the defe
It is debated whether cancer patients treated with chemotherapy can mount an adequate response to vaccination. Material and methods. Ninety-six adult outpatients with cancer, who were undergoing chemotherapy and/or monoclonal antibody, tyrosine kinase inhibitor, irradiation or corticosteroid treatments, were studied. Two doses of the pandemic influenza A(H1N1)/09 AS03-adjuvanted split virion vacci
Drug repurposing or re-profiling has become an effective strategy to identify novel indications for already-approved drugs. In this study, peptidomimetic FDA-approved HIV/HCV inhibitors were explored for their potential to be repurposed for the inhibition of the replication of dengue (DENV) and chikungunya virus (CHIKV) by targeting the NS2B-NS3 and NSP2 protease, respectively. MM/GBSA-based bindi
Inbjudan I n s t i t u t i o n e n f ö r m i l j ö v e t e n s k a p l i g u t b i l d n i n g 2015-08-14 PRELIMINÄRT SCHEMA PRELIMINÄRT Schema för MVET10 miljöskydd, 15 hp ht 15 Kurstid: 31 augusti – 1 november 2015 Kursansvarig: Högni Hansson 0721-55 56 48, hogni.hansson@cec.lu.se Introduktion: måndagen den 31 augusti 2015, Ekologihuset, Maskrosen, kl. 10.15-11.00. Lärare: Högni Hansson hogni.ha
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/schema_mvet10_ht15_v2-2.pdf - 2026-07-18
Inbjudan Besöksadress Telefon dir Växel E-post Internet Sölvegatan 37 046-222 9322 046-222 0000 Hogni.Hansson.@mv.lu.se http://www.miljovetenskap.lu.se 223062 Lund Ins t i tu t ionen för mi l jövetenskapl ig u tb i ldn ing PRELIMINÄRT Schema för MVET10 miljöskydd, 15 hp ht 14 Kurstid: 1 september – 30 oktober 2014 Kursansvarig: Högni Hansson 0721-55 56 48, hogni.hansson@mv.lu.se Introduktion: månd
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/schema_mvet10_miljoskydd.pdf - 2026-07-18
The results from a new numerical method for simulating the strength and fracture locations of small glass specimens subjected to double ring bending are compared with experimental data. The method implements the weakest-link principle while assuming the existence of Griffith flaws. A Weibull distribution for the strength is simulated based on a single population of Pareto distributed crack sizes.
The world continues to boil due to capital’s incapacity to resolve its climatic contradictions. Stratospheric Aerosol Injection (SAI), a technological process theorised to instantly reduce global temperatures, has piqued the interest of a now desperate ruling class. Given its worldwide impacts, enormous risks, and capitalist- imperialist reproductive capacities, it is crucial to engage with SAI wh
As a consequence of the current global warming debate, many companies are today working towards minimizing their operations’ effect on the environment. The Swedish firm Ångpanneföreningen (ÅF), offers environmental consulting services through its EHS department (Environment, Health and Safety). The department’s largest business areas are services regarding state-regulated emission permits and meas
Phenological vegetation characteristics are valuable inputs to several ecosystem-related models: including carbon exchange and climate change. Phenological characteristics are effective measures of changes in vegetation in an area and are subject to the seasonal and inter-annual climatic variations. In arid and semi-arid ecosystems, precipitation is the main driving factor for changes in vegetatio
Long time series of satellite remotely sensed Normalized Difference Vegetation Index (NDVI) as an indicator of vegetation greenness can be used in a broad range of research topics such as climate change, vegetation dynamics and desertification monitoring. The first phase of this study tests a practical method using Hyperion imagery onboard on Earth Observing-1 (EO1) spacecraft for simulation of MO
