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Biological predictors of insulin resistance associated with posttraumatic stress disorder in young military veterans

Posttraumatic stress disorder (PTSD) is associated with increased risk for Type 2 diabetes and cardiovascular disease (cardiometabolic disease), warranting research into targeted prevention strategies. In the present case–control study of 160 young (mean age 32.7 years) male military veterans, we aimed to assess whether PTSD status predicted increased markers of cardiometabolic risk in otherwise h

Implementation of the Trade Secrets Directive into National Law: Portugal and Spain

The protection of trade secrets in Portugal and Spain has been derived from general legal principles (of Civil Law, Penal Law and Unfair Marketing Law). This chapter on implementation of the Trade Secrets Directive (TS Directive) in Portugal and Spain presents the traditional views and positions and the implementation of the TS Directive into the respective national legal orders.In Portugal, imple

Collecting data for quality improvement and research in Swedish healthcare, and the individual patient's right and ability to protect their privacy

During the last decades, there has been continuous development of nationwide quality registries to assess healthcare and to do research in Sweden. An important background motive is the demographic transition resulting from an increasingly ageing population as one of the most important challenges of our time and a growing concern in many European countries and elsewhere. One condition for meeting t

Predicting institutional long-term care admission in dementia: a mixed-methods study of informal caregivers' reports

AimTo investigate agreement between: (1) expected reasons and actual reasons for admission of people with dementia according to informal caregivers; (2) scores on measurement instruments prior to admission and the actual reasons for admission according to informal caregivers. BackgroundTimely admission of people with dementia is a crucial issue. Information is highly warranted on whether informal

Baseline IGF-I Levels Determine Insulin Secretion and Insulin Sensitivity during the First Year on Growth Hormone Therapy in Children Born Small for Gestational Age. Results from a North European Multicentre Study (NESGAS)

Objective: Developmental programming alters growth and metabolic outcome in children born small for gestational age (SGA). We explored insulin and glucose metabolism in SGA children treated with a fixed GH dose over 1 year. Methods: In the North European Small for Gestational Age Study (NESGAS), 110 short SGA children received GH at 67 mu g/kg/day for 1 year. Insulin secretion was assessed by acut

Chondroitin sulfate proteoglycans and microglia prevent migration and integration of grafted Muller stem cells into degenerating retina

At present, there are severe limitations to the successful migration and integration of stem cells transplanted into the degenerated retina to restore visual function. This study investigated the potential role of chondroitin sulfate proteoglycans (CSPGs) and microglia in the migration of human Muller glia with neural stem cell characteristics following subretinal injection into the Lister hooded

Orthopaedic measurements with computed radiography. Methodological development, accuracy, and radiation dose with special reference to the weight-bearing lower extremity and the dislocating patella

Popular Abstract in Swedish Digital bildteknik dominerar snart all bildhantering inom alla delar av samhället. Målsättningen med denna avhandling var att utveckla en undersökningsmetod för mätning av knäleden i belastat läge med hjälp av digital bildplatteteknik. Vad är bildplatteteknik? Traditionellt har röntgenbilder framställts med hjälp av fotografisk film. De framkallade bilderna har sedan The overall aim of this study was to develop and evaluate a measurement system for computed radiography (CR) and Picture Archiving and Communication Systems (PACS), permitting measurements of long distances and angles in and between related images. The developed measurement system, which was based on the QUESTOR Precision Radiography (QPR) system, was applied to the weight-bearing knee with specia

Luftföroreningar vid svetsning

PIXE-analyser kan utföras med utvecklad analysuppställning med noggrannhet och precision av c:a 10 % och med hög analyskapacitet. Ett dataprogram för evaluering av räntgenspektra presenteras. Inverkan av provtjocklek vid PIXE-analys av inhomogena prov har studerats och korrektioner föreslås. Fluorinnehållet i filterprov har bestämts, samtidigt med PIXE-analys, genom utnyttjande av en kärnfysikalis

From Medication to Education - People with autism in adult psychiatry

This dissertation concerns the field of applied psychiatry and focuses on the problems that are associated with the care and treatment of adult patients with autism spectrum disorders. The conditions that are described are valid for Swedish psychiatry and cannot be directly generalized to conditions outside of the country.

Some consequences of atmospheric dispersion for ELTs

Previously the effect of atmospheric dispersion on telescope performance has attracted only relatively little attention. This may be due to the fact that the dispersion effects have been evaluated in relation to the size of the diffraction limited resolution angle of current telescopes, or to seeing limited telescopes. However, since the resolution angle is inversely proportional to telescope diam

A new concept for large deformable mirrors for extremely large telescopes

For extremely large telescopes, there is strong need for thin deformable mirrors in the 3-4 m class. So far, feasibility of such mirrors has not been demonstrated. Extrapolation from existing techniques suggests that the mirrors could be highly expensive. We give a progress report on a study of an approach for construction of large deformable mirrors with a moderate cost. We have developed low-cos

Varandra som vänner och fiender - en idékritisk undersökning om kontraktet och dess grund.

Popular Abstract in Swedish Den här boken handlar om ömsesidighet i sociala relationer - om vänskap. Den handlar också om de moraliska och rättsliga normer och föreställningar som istället främjar ensidiga, eller till och med direkt fientliga, relationer. Arbetet utgår från vissa centrala punkter i den aristoteliska etiken. Undersökningen kretsar kring de värden som konstituerar den sociala relatiThis is a book about reciprocity in social relationships - about friendship. It also deals with the moral and legal norms which, conversely, promote one-sided and even directly hostile relationships. The starting-point for this work is certain central elements in Aristotelian ethics. The study revolves around the values which constitute the social relationship of friendship and the central questio

Dynamic Glucose-Enhanced (DGE) MRI: Translation to Human Scanning and First Results in Glioma Patients.

Recent animal studies have shown that D-glucose is a potential biodegradable MRI contrast agent for imaging glucose uptake in tumors. Here, we show the first translation of that use of D-glucose to human studies. Chemical exchange saturation transfer (CEST) MRI at a single frequency offset optimized for detection of hydroxyl protons in D-glucose (glucoCEST) was used to image dynamic signal changes

Personalized Support with ‘Little’ Data

In this paper we look at opportunities to support the creation of value for all through the use of end-user-owned Virtual Personal Assistant. We use a chat-bot as example of technology with a possibility for transferring and diffusing new functionality, features and capabilities. This category of software can create potential value through its AI and natural language processing combined with emula