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To analyze visual outcomes after cataract surgery in patients with previous corneal refractive surgery.

Delayed gadolinium-enhanced MRI of cartilage is a technique for studying the development of osteoarthritis using quantitative T(1) measurements. Three-dimensional variable flip angle is a promising method for performing such measurements rapidly, by using two successive spoiled gradient echo sequences with different excitation pulse flip angles. However, the three-dimensional variable flip angle m

The study aimed to assess, in multiple populations, the role of HLA alleles on early and late age at onset of type 1 diabetes. Stepwise linear regression models were used to determine which HLA class I and class II risk alleles to include. High-resolution genotyping data for patients from the Type 1 Diabetes Genetics Consortium (T1DGC) collection (n = 2,278) and four independent cohorts from Denma

Carotid intima media thickness (IMT) progression is increasingly used as a surrogate for vascular risk. This use is supported by data from a few clinical trials investigating statins, but established criteria of surrogacy are only partially fulfilled. To provide a valid basis for the use of IMT progression as a study end point, we are performing a 3-step meta-analysis project based on individual p

The predominantly populated conformation of carbohydrates in solution does not necessarily represent the biologically active species; rather, any conformer accessible without too large an energy penalty may be present in a biological pathway. Thus, the conformational preferences of a naphthyl xyloside, which initiates in vivo synthesis of antiproliferative glycosaminoglycans, have been studied by

Rare-variant association studies in common, complex diseases are customarily conducted under an additive risk model in both single-variant and burden testing. Here, we describe a method to improve detection of rare recessive variants in complex diseases termed RAFT (recessive-allele-frequency-based test). We found that RAFT outperforms existing approaches when the variant influences disease risk i

A search has been performed for photons originating in the decay of a neutral long-lived particle, exploiting the capabilities of the ATLAS electromagnetic calorimeter to make precise measurements of the flight direction of photons, as well as the calorimeter's excellent time resolution. The search has been made in the diphoton plus missing transverse energy final state, using the full data sample

This study analyzes (a) the relation between injury severities, the age of the bicyclist and the speed environment at accident locations (mean travel speed of the traffic flow involved in the accident) where a bicyclist was struck by a motorized vehicle and (b) how these relations differ from those for struck pedestrians. Accident data from Sweden for the years 2004-2008 was used to identify accid

Background: Chronic low-grade inflammation and associated insulin resistance and metabolic abnormalities have been proposed as 'common soil' for diabetes mellitus (DM) and cardiovascular disease (CVD). This paper aimed to investigate the inflammatory profiles of DM and CVD and to distinguish their shared and specific markers. Methods: Based on the Malmö Diet and Cancer cohort, total and differenti

To date, little is known about the effects of violence on the educational outcomes of adolescents in disadvantaged communities in South Africa. In response, self-report data were collected from a socioeconomically disadvantaged sample of 503 adolescents aged 10 to 18 participating in a child abuse prevention trial in the Eastern Cape. Adolescents were purposively selected in the trial. This study

This article explores the similarities between the two most successful Swedish films of the past years. Through a focus on the two elderly protagonists the article discusses how the films acknowledge challenges in these men’s lives and in both contemporary and past society, but effectively repackage any serious issue in a form that remains palatable to audiences in Sweden and internationally. Them

Hemoglobin (Hb)-based oxygen carriers (HBOCs) have been engineered to replace or augment the oxygen carrying capacity of erythrocytes. However, clinical results have generally been disappointing, in part due to the intrinsic oxidative toxicity of Hb. The most common HBOC starting material is adult human or bovine Hb. However, it has been suggested that fetal Hb may offer advantages due to decrease

The analysis of stable isotopes assisted in identifying that groundwater in the Punata alluvial fan is mainly recharged by heavy flash floods, and the recharge from rainfall is of less importance. In addition, the hydrochemical analysis identified the Pucara River as the main source of recharge. Other streams in the north and northwest of the fan do not seem to contribute to the recharge. The hydr

Stomatopods have an elaborate visual system served by a retina that is unique to this class of pancrustaceans. Its upper and lower eye hemispheres encode luminance and linear polarization while an equatorial band of photoreceptors termed the midband detects color, circularly polarized light and linear polarization in the ultraviolet. In common with many malacostracan crustaceans, stomatopods have

Recent studies have focused on investigating different factors that may affect heart rate variability (HRV), pointing especially to the effects of age, gender and stress level. Other findings raise the importance of considering the respiratory frequency in the analysis of HRV signals. In this study, we evaluate the effect of several covariates on the parameters of a stochastic model for HRV. The d

Home energy management systems (HEMS), providing energy feedback and smart features through in-home displays, have the potential to support more sustainable household decisions concerning energy consumption. However, recent findings from European smart metering trials have reduced the optimism, suggesting only modest savings from energy feedback. In this paper, we investigate the potential of HEMS

A decision is the result of comparing one or more alternatives with respect to one or more criteria that we consider relevant to the decision. Decision making can be considered as one of the most important challenges that analysts and experts encounter to solve complex problems. In recent decades, different methods and algorithms have been presented to support decision making. Multi-criteria analy

Islet autoantibodies (IAs) precede the clinical onset of type 1 diabetes (T1D); however, the knowledge is limited about whether the prodrome affects complete blood counts (CBCs) in 4- to 12-year-old children with increased genetic risk for T1D. This study tested whether CBCs were altered in 4- to 12-year-old children without (n = 376) or with one or several IAs against insulin, GAD65, or IA-2 (n =