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Malignant melanoma is among the most aggressive skin cancers and it has among the highest metastatic potentials. Although surgery to remove the primary tumor is the gold standard treatment, once melanoma progresses and metastasizes to the lymph nodes and distal organs, i.e., metastatic melanoma (MM), the usual outcome is decreased survival. To improve survival rates and life span, advanced treatme
The fate options of hematopoietic stem cells (HSCs) include self-renewal, differentiation, migration, and apoptosis. HSCs self-renewal divisions in stem cells are required for rapid regeneration during tissue damage and stress, but how precisely intracellular calcium signals are regulated to maintain fate options in normal hematopoiesis is unclear. S100A6 knockout (KO) HSCs have reduced total cell
Neurogenesis, the production of new neurons from neural stem cells, dramatically decreases during aging concomitantly with increased inflammation both systemically and in the brain. However, the precise role of inflammation and whether local or systemic factors drive the neurogenic decline during aging is poorly understood. Here, we identify CXCR5/5/CXCL13 signaling as a novel regulator of neuroge
Noroviruses are the major cause for viral acute gastroenteritis in the world. Despite the existing infection prevention strategies in hospitals, the disease continues to spread and causes extensive and numerous outbreaks. Hence, there is a need to investigate the possibility of airborne transmission of norovirus. In this study, we developed an experimental setup for studies on the infectivity of a
Over the last decade, universities and other institutions of higher education (HEIs) worldwide have witnessed an evolution to their role relative to society – with increasing attention to external engagement and expectations on societal impact. This has fostered an upswing in activity as research and innovation funding bodies and universities alike explore new approaches to working with external eOver the last decade, universities and other institutions of higher education (HEIs) worldwide have witnessed an evolution to their role relative to society – with increasing attention to external engagement and expectations on societal impact. This has fostered an upswing in activity as research and innovation funding bodies and universities alike explore new approaches to working with external e
Ambient pressure x-ray photoelectron spectroscopy (APXPS) can provide a compelling platform for studying an analyte's oxidation and reduction reactions in solutions. This paper presents proof-of-principle operando measurements of a model organometallic complex, iron hexacyanide, in an aqueous solution using the dip-and-pull technique. The data demonstrates that the electrochemically active liquid
In order to meet the increasing needs of housing and services in urban areas, cities are densified. When densifying a city, it is important to provide good living conditions while maintaining a low environmental impact. To ensure this, the urban planning process should include simulations of e.g. noise and daylight conditions. In this paper we describe a newly started projected directed towards th
BACKGROUND: Conventional dosages of cytostatics in mg/m2 will cause marked variations in systemic exposure, resulting in over- and under-treatment, at least with respect to side effects.PATIENTS AND METHODS: We are conducting a randomized adjuvant study for breast cancer patients younger than 60 years of age with > or = 70% risk of recurrence within five years. The first 89 consecutive patients wh
Annual Report Lund university HUmanities Lab | 2015 3 Annual Report 2015 The past year, 2015, was eventful for Lund University Humanities Lab. It was our first year as a ’distributed Lab’ – now with research facilities in the two buildings of the Joint Faculties of Humanities and Theology, namely the Lab@SOL and the Lab@LUX. Over the year, we have developped new routines for organising demos and v
https://www.humlab.lu.se/fileadmin/user_upload/humlab/typo3/About/Annual_reports/LU_Humlab_AnRep_2015_webb.pdf - 2026-07-02
We created an AI support for diagnosis in dyspneic adults at time of triage in the emergency department.Complete data from an entire regional health care system was analyzed, to find AI-derived, unknown, important diagnostic predictors. Most important were prior diagnoses of heart failure or COPD, daily smoking, atrial fibrillation/flutter, life difficulties and maternal care.Sensitivity for AHF,
Sea salt aerosol particles are highly abundant in the atmosphere and play important roles in the global radiative balance. After influence from continental air, they are typically composed of Na+, Cl-, NH4+, and SO42- and organics. Analogous particle systems are often studied in laboratory settings by atomizing and drying particles from a solution. Here, we present evidence that such laboratory st
Exposure to natural environments is thought to benefit mental and physical health. A better understanding of the interplay between the individual and the environment in relation to public health is imperative in light of the joint biodiversity, climate, and health crises. This study aimed to 1) identify Body Mass Index (BMI) trajectories in the Scania Public Health Cohort (SPHC), 2) characterise t
Knowledge of human fetal blood development and how it differs from adult blood is highly relevant to our understanding of congenital blood and immune disorders and childhood leukemia, of which the latter can originate in utero. Blood formation occurs in waves that overlap in time and space, adding to heterogeneity, which necessitates single-cell approaches. Here, a combined single-cell immunopheno
Despite low or undetectable plasma viral load, people living with HIV-2 (PLWH2) typically progress toward AIDS. The driving forces behind HIV-2 disease progression and the role of viremia are still not known, but low-level replication in tissues is believed to play a role. To investigate the impact of viremic and aviremic HIV-2 infection on target and bystander cell pathology, we used data-indepen
During the early modern period Swedish society was structured by a variety of hierarchies, and the principle of filial deference, or the obedience and recognition children–young or adult–were expected to show their parents, was more or less absolute. These ideas of family hierarchy influenced marriage laws and the formal rules of who was allowed to marry whom. During the 1700s the number of applic
Background. The estimation of glomerular filtration rate (GFR) is one tool to detect renal disease. The most used biomarker remains serum creatinine and the European Kidney Function Consortium (EKFCcrea ) equation is the most validated in Europe. More recently, cystatin C has been proposed as a biomarker. We studied the performances of the EKFC equations in a large cohort of subjects according to
Nyhetsbrev 2016 till dig som deltar i ett världsunikt projekt Stort deltagande när GÅS i Malmö hade Öppet Hus Anna Cewe Jönsson, deltagare, till höger, får tips av Zinka Tucek, GÅS-medarbetare, till vänster. Ett par hundra personer hade hörsammat vår inbjudan och kommit till Öppet Hus för GÅS-deltagare i Malmö den 18 maj. Evenemanget började redan i foajén till Jubileums- aulan på Skånes universit
https://www.geriatrik.lu.se/sites/geriatrik.lu.se/files/nyhetsbrev2016.pdf - 2026-07-02
BACKGROUND AND OBJECTIVES: Atrial fibrillation (AF) is associated with inflammation systemically and in the atrial tissue. Oxidized low-density lipoprotein (LDL) is increased in patients with AF and is suggested to be one of the molecules that drives inflammation. Autoantibodies against oxidized LDL and apolipoprotein B100, the protein component of LDL, are linked to atherosclerotic disease. Howev
Research Reports in Social Work 2012 ersattes rapportserien Meddelanden från Socialhögskolan med Research Reports in Social Work. På denna sida hittar du länkar till publikationer som går tillbaka till 1981. 20182018:6 Äldreomsorgsförsäkring - ett svårfångat alternativ: Några nedslag i den svenska debatten av Per Gunnar Edebalk2018:5 Granskningssamhällets krav och civilsamhällets (re)aktioner. Rap
https://www.soch.lu.se/forskning/research-reports-social-work/arkiv - 2026-07-01
