Sökresultat

En dialog med ekonomen Hal Varian om det digitala skiftet i ekonomin, regleringen av digitala marknader och framtiden

Är doktrinen om ”alla människors lika värde” tillämpbar också på framtida, ännu icke levande personer? Artikeln argumenterar för ett jakande svar och ger därmed ett bidrag till hur denna vanliga moraliska övertygelse ska förstås och ger dessutom nya argument för omsorg gentemot framtida personer. Doktrinen tolkas som en kritik av handlingar och situationer snarare än som en fullständig värdering a

Background: Less than half of patients with major depressive disorder (MDD) respond to their first antidepressant trial. Our understanding of the underlying mechanisms of selective serotonin reuptake inhibitors (SSRIs) remains poor, and there is no reliable method of predicting treatment response. Methods: Thirty-seven MDD subjects and 41 healthy controls, somatically healthy and medication-free f

Kognitiva och emotionella svårigheter är vanliga hos personer som överlevt ett hjärtstopp. Rutinerna för uppföljning efter hjärtstopp varierar stort mellan olika regioner och sjukhus i Sverige.För att förbättra vården har Svenska HLR-rådets arbetsgrupp för vård efter hjärtstopp tagit fram svenska riktlinjer för uppföljning efter hjärtstopp. According to previous research, a structured cardiac arrest follow-up may contribute to identifying health problems and the potential need of support among survivors and their relatives. However, a survey on post CA care and follow-up in Sweden, reported a lack of structure and major variations among Swedish hospitals. In 2016, Swedish guidelines were published with the aim to improve care. Accord

The purpose of this studywas to investigate the prognostic value of lactate at admission, 12-h lactate and 12-h lactate clearance for 30-day survival in comatose patients admitted after out of hospi tal cardiac Arrest (OHCA). Although measures of lactate have been successfully implemented in sepsis and trauma care, most OHCA studies are biased due to design and the results are conflicting. This is

The effect of different glutamate‐receptor antagonists on the induction of cortical spreading depression of Leao and of cortical anoxic membrane depolarization were investigated in the anaesthetized rat. Spreading depression (SD), elicited by mechanical stimulation of the cortical surface, was inhibited by the non‐competitive N‐methyl‐d‐aspartate (NMDA)‐receptor blocker, (±)‐5‐methyl‐10,11‐dihydro

The effect of cerebral ischemia on the activity of pyruvate dehydrogenase (PDH) enzyme complex (PDHC) was investigated in homogenates of frozen rat cerebral cortex following 15 min of bilateral common carotid occlusion ischemia and following 15 min, 60 min, and 6 h of recirculation after 15 min of ischemia. In frozen cortical tissue from the same animals, the levels of labile phosphate compounds,

The effect of an α-2 receptor antagonist, idazoxan, on ischemic neuronal damage in the hippocampus and neocortex was studied in rats following 10 min of forebrain ischemia. Idazoxan was given 0.1 mg/kg i.v. immediately after recirculation, followed by 48 h of continuous infusion at a rate of 10 μg/kg/min. A histopathological examination of the CA1 region of the dorsal hippocampus and neocortex fro

Changes in the levels of arachidonic acid during ischemia in selectively vulnerable areas of the hippocampus were studied in the rat brain. Since neurons in the CA1 region are more vulnerable to ischemia than neurons in the adjacent CA3 region, the release of arachidonic acid in these two regions was measured during decapitation ischemia of 4- to 12-min duration. The concentration of free arachido

This study addresses the question of whether the cyclooxygenase inhibitors indomethacin and diclofenac and the glucocorticosteroid dexamethasone ameliorate neuronal necrosis following cerebral ischemia. In addition, since these drugs inhibit the production of prostaglandins and depress phospholipase A2 activity, respectively, the importance of free fatty acids (FFAs) on the development of ischemic

The recent Company of Biologists workshop 'Growth, Division and Differentiation: Understanding Developmental Control', which was held in September 2011 at Wiston House, West Sussex, UK, brought together researchers aiming to understand cell proliferation and differentiation in various metazoans, ranging from flies to mice. Here, we review the common themes that emerged from the meeting, highlighti

In the last few decades it has become ever clearer that humankind faces many serious environmental challenges. As the corporate sector has been identified as an important actor to address these challenges, understanding why certain companies choose to adopt sustainability initiatives, while others do not, is an important question. However, little previous research has addressed how sustainability

Biografisk skildring av lundaalumnen och konstnären Wilhelm Angeldorff (1864-?) inklusive uppgifter om dennes föräldrar Christopher Olofsson Angeldorff (1808-1866) och Helène Angeldorff, född Österberg (1832-1911).