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Neurotrophic Factor Receptors in the Normal and Injured Visual System : Focus on Retinal Ganglion Cells

The focus of this thesis is the life and death of adult retinal ganglion cells (RGCs). RGCs are neurons that convey visual information from the retina to higher centers in the brain. If the optic nerve is transected (ONT), adult RGCs die by a form of cell death called apoptosis, and a general hypothesis is that neurotrophic factors can support the survival of injured neurons. With the intention to

Cellobiose dehydrogenase on electrodes - an electrochemical biosensor for various analytes tunable by positive charges

Cellobiose dehydrogenase (CDH) is a sugar oxidizing enzyme secreted by various species of wood degrading fungi to assist the process of wood degradation. It can oxidise analytically relevant sugars as cellobiose, lactose or glucose leading to a gain of two electrons per sugar molecule. CDH consists of a flavin containing catalytic domain (DH) and a haem containing electron mediating domain (CYT).

Command or invitation? How Jesus got his first disciples

In the beginning of the public career of Jesus, Mark and Matthew both narrate how Jesus “calls” four fishermen to follow him which results in an immediate positive response (Mark 1:16–20/Matt 4:18–22). How is the reader to understand Jesus’ calling of disciples? Is Jesus making an authoritative command or does he merely invites the fishermen? What is Jesus doing when he “calls” his disciples? Thes

Experimental phenomenology in research on spirituality

The purpose of the present chapter is to outline the principles of experimental phenomenology as an approach to research on spirituality. Experimental phenomenology is the investigation of phenomenological practices and their impact. Essential to phenomenological practices is that they involve intentional variations of experiencing by means of changes in the direction of attention and the choice o

Kinetics and Mechanism for Chloride Anation of Some Platinum(IV) Aqua Complexes in the Presence of Platinum(II))

Chloride anations of PtCl5H2O−, trans-PtCl4(H2O)2 and trans-Pt(CN)4ClH2O− in the presence of PtCl42− have been studied at 50°C in 1.00M perchloric acid medium. It is shown that PtCl5H2O− is formed as the primary reaction product in the two last-mentioned anations. This is not compatible with the generally used mechanism for platinum(II)-catalyzed platinum (IV) substitutions, which gives PtCl62− as