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Nik-related kinase: A New IL-10 Regulator Our body is constantly exposed to microscopic organisms called microbes. Some of these organisms are harmless while others are able to cause infection and damage. Thus, our body has defense mechanisms that include the immune system. Macrophages are cells that belong to the immune system and have key roles in defense against infection, wound healing, and r

Breast cancer is the most common type of cancer worldwide with an estimate of 2.3 million new cases in 2020, and the number one cause of cancer-related deaths in women. While survival rates are high in many high-income countries, with a five year relative survival rate of 85% and more, the respective survival rates are poor in many middle- and low-income countries, with rates as low as 12% in Kyad

This thesis has its focus on the interaction between competition law and the public procurement regime. Since the two systems have the same objective of the creation of an internal market it is vital that the two systems reach coherence. Despite this there is now express provision on the importance to fight anti competitive behaviour in the Public Sector Directive 2004/18/EC. On March 28th 2014 th

Background Supply chains in low margin, high innovation speed industries with strong customers generate a highly competitive environment. The conditions for such environment are continuously changing and put high demands on its actors. FlatFrog is a case company, which was founded in 2007 and develops a unique touch technology targeting a wide range of screens sizes and applications. External capi

Förevarande uppsats behandlar de utredningar om vårdnad-, boende- och/eller umgänge vilka kan företas i tvister om detsamma. Uppsatsen besvarar frågorna om när och hur reglerna om sådana utredningar tillämpas. Vidare behandlas de brister som finns i utredningar av sådant slag, samt delar av den kritik utredningarna utsatts för. Vid tvister om vårdnad-, boende- och/eller umgänge är vårdnadsutredninThe present essay aims to illuminate the custody reports possible to execute during a custody dispute, when and how the legal rules about custody reports applies, and how the custody report is executed. When a court has to decide if the custody of a child henceforth shall be joint or sole, or where the child henceforth shall live, and in which extent the child shall have right to visitation with t

Every year people are vacationing thousands of miles away from home. Low cost tickets and packaged trips have made exotic tourism more affordable. The mass tourism developed during the 50s and today, the travelling- and tourism industry is the third biggest industry in the world. Only the oil industry and the building sector are bigger. The biggest environmental load caused by tourism is the trans

Populärvetenskaplig sammanfattning: De begravda jordmånsbildningarna vid Sandhammaren och Skanörs ljung, södra Sverige, är lokaliserade inom kustnära dynlandskap som har bildas i response till land-och havsnivåförändringar efter den sista istiden (efter ca. 10 000 år sedan). Jordmånerna är begravda av flygsand och karakteriseras av flera organiska lager med tillhörande urlaknings-och anrikningshorThe palaeosoils at Sandhammaren and Skanörs ljung, southern Sweden, are located within a coastal dune landscape that developed in response to Holocene land/sea changes. These buried soils are characterised by several organic layers including pedological horizons. They were studied for fossil pollen, and soil chemistry (iron, aluminium, manganese, phosphorous, carbon and pH) in order to appreciate

There are competing standards regarding the definition of the crime of “enforced disappearance” under international law. When criminalizing enforced disappearance at the national level as part of their obligations under international law, States which adopt a more narrow definition of enforced disappearance provided in the Rome Statute require victims of enforced disappearance to prove the existen

Genom freden i Roskilde 1658 kunde Sverige tillskansa sig det tidigare danska Skåne. Fredsavtalet garanterade skåningarna rätten till, bland annat, dansk lag och tidigare danska privilegier. Statens arbete mot uniformitet i provinsen, genom att försvenska området, tog dock sakta men säkert vid, och 1683 var arbetet utfört och uniformiteten införd. Huvudsyftet med uppsatsen har varit att klargöra vIn 1658, the former Danish region of Scania was ceded to Sweden due to the Treaty of Roskilde. The treaty also guaranteed the Scanian population its right to maintain their Danish law and retain their former Danish privileges. Despite this, the state soon started to work towards uniformity between Scania and Sweden by a process known as Swedification, a process which was completed in 1683. The mai

Batch high-shear mixers are used in a variety of different processing industries,such as the pharmaceutical, chemical and food industries. One company that utilize this type of mixers is Tetra Pak. High-shear mixers can be used for many different mixing scenarios, but only liquid-liquid mixing is discussed in the thesis. The batch high-shear mixer is constructed with a rotor-stator at the bottom o

Examensarbetet jämför tre olika metoder för dimensionering av en spont. Syftet med arbetet är att utreda hur de valda beräkningsmetoderna inverkar på dimensionerande snittmoment och dimensionerande förankringskrafter samt att undersöka hur resultaten från de olika beräkningsmetoderna varierar vid ändring av ingående parametrar. De tre beräkningsmetoder som jämförs är den analytiska metoden från SThis master thesis compares three different methods for dimensioning a sheet pile wall. The purpose is to investigate how the chosen calculation methods affect dimensioning moments and anchoring forces in a sheet pile wall and to investigate how the results from the different calculation methods vary when changing the input parameters. The three calculation methods that are compared are the analy

I den första svenska jämställdhetslagen från 1979 skyddades bara diskrimineringsgrunden kön. Redan då insåg lagstiftaren att det behövdes en bevislättnad eftersom diskriminering bygger på att man vet orsaken till att arbetsgivaren har handlat på ett visst sätt. Jämställdhetslagens bevisbörderegel skapades som en presumtionsregel. En presumtionsregel innebär att arbetstagaren ska bevisa vissa omstäIn the first equality act of Sweden from 1979, the scope of the discrimination protections afforded under the act were limited by the gender of a given party. Already at that time, the legislator saw a need for a relaxation of the burden of proof as previously, discrimination matters turned on the requirement that the claimant be cognizant of why the defendant had acted in a certain manner. The r

Fjärrvärme har en betydande roll i det svenska energisystemet där många är beroende av att systemet ska fungera optimalt. Trots den generellt höga leveranssäkerheten i dagens system är oplanerade leveransavbrott är något som sker tidvis. I Sverige började många fjärrvärmenät byggas ut i mitten av 1900-talet och mängden skador i äldre ledningar förväntas öka med tiden. Att ersätta gamla ledningar iDistrict heating plays a significant role in the Swedish energysystem where many are dependent on the district heating working optimally. The system in general has a high security of supply, but unplanned interuptions in the supply do ocasionally occur. Many of the district heating networks in Sweden began construction in the middle of the last century and some of the old pipes are expected to see

Allergic rhinitis is a common disease affecting millions of people worldwide. Biocare Copenhagen A/S, a Danish biotechnology company decided to screen a number of probiotic lysates, with the aim to identify suitable strains with potential anti-allergic properties, that could regulate production of cytokines and divert the immune system in a regulatory or tolerant mode. People suffering from aller

År 2011 infördes entreprenörskap i den svenska skolans läroplaner. På 1980-talet ansågs dock utbildningsorganisationen Ung Företagsamhet (UF), som fokuserar på entreprenörskapsutbildning för ungdomar, vara ideologiskt kontroversiell. Under loppet av 30 år har synen på entreprenörskap och UF:s status förändrats i grunden. Denna avhandling undersöker hur och varför entreprenörskap blev ett kunskapsoIn 2011, entrepreneurship was added to the curricula of Swedish schools at all levels. In the 1980s, however, the educational organization Junior Achievement (JA), that focuses on entrepreneurship education for young people, was considered ideologically controversial. Over the course of 30 years, the view of entrepreneurship and the status of JA has changed fundamentally. This thesis investigates

To achieve a kind of neutrality between insid-ers of close companies and other taxpayers in Swedish society the Swedish tax law states that capital gains, which derive from ownership in close companies, and dividends distributed to owners of close companies will be subject to high taxation. However, changes in owner-ship may involve a tax reduction. The estab-lishment of a foreign business can be

Förorenaren betalar är en ekonomisk princip som internaliserar externa kostnader. Principen är således en metod genom vilken kostnader för förorening kan bli fördelade. Principen kan också beskrivas genom att använda ett rättviseargument, eftersom det kan anses rättvist att förorenaren ska betala för den förorening som han bidragit till. Förorenaren betalar har använts i internationell rätt och anThe polluter pays principle is an economic principle through which external costs can be internalised. The principle is thus a way of allocating costs for pollution. The principle can also be described using a fairness argument, where it would seem fair that the polluter pays the costs for the pollution which he has contributed to. It has been extensively used in international law, and has been re

Tutors: Stefan U Klingberg, Director Strategic Planning, Scania CV AB Ulf Paulsson, Ph.D in Engineering, Department of Business Administration Malin Olander Roese, Department of Design Sciences, LTH Issue of study: Services dominate the economy of today why it becomes essential for companies to add value through services. Still many companies fail to do so. The main reason is existing knowledge

One of the cleanest ways of transporting goods is at sea. However, the emissions from ships increase and with a wider knowledge about the environmental consequences caused by the emissions, requisite regulations are needed. This thesis deals with air emissions of sulphate (SOx) - and nitrogen oxides (NOx). These emissions cause negative environmental effects both by direct pollution and by forming