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Epileptic brain damage : pathophysiology and neurochemical pathology.

In this chapter, the pathophysiology and neurochemical pathology of epileptic brain damage is discussed on the basis of an integrative approach in which a comparison is made to cell necrosis resulting from ischemia and hypoglycemia. Two main questions are asked. First, is the brain damage resulting from these three disorders of cerebral energy metabolism similar in distribution and structural char

Residual adverse changes in arterial endothelial function and LDL oxidation after a mild systemic inflammation induced by influenza vaccination

Background. Several clinical studies have suggested possible increase in cardiovascular risk during and in the first weeks after an acute inflammatory disease. Using influenza vaccine as inflammatory stimulus, we investigated whether arterial endothelial dysfunction could persist beyond the inflammatory state, and whether amplified oxidative modification of low-density lipoprotein (LDL) accompanie

Association of Neuropathologically Confirmed Frontotemporal Dementia and Alzheimer Disease With Criminal and Socially Inappropriate Behavior in a Swedish Cohort

Importance Criminal and socially inappropriate behavior is encountered among patients with dementia, and it is sometimes the first sign of a dementing disorder. This behavior constitutes a significant burden to society, patients’ relatives, and patients themselves. Objectives To investigate and compare the prevalence and type of criminal and socially inappropriate behavior, as well as recurrence

Spatial vision in diverse invertebrates

Förmågan att uppfatta ljus och vilken riktning det kommer från är utomordentligt användbart för djur. Därför är det inte förvånande att denna förmåga återfinns hos i stort sett varje större djurgrupp, även bland de som anses enkla, såsom koraller och spolmaskar. Endast några få djurgrupper har dock, under evolutionens gång, utvecklat verkligt bra ögon som snabbt kan identifiera objekt av djurens eLight-detection provides incomparabaly rapid information at a range of time scales and, consequently, directional photoreception is found in almost every major metazoan clade. Conversely, a much smaller cohort have evolved sophisticated high resolution vision, which facillitates complex tasks via the detection of fast or small objects,. such as courtship and high-speed pursuit of prey. A few such

Övervakning av fåglarnas populationsutveckling. Årsrapport för 2013.

I denna rapport redovisas populationstrender för 178 svenska fågelarter för åren 1975–2013. Fåglarna har räknats på vintern och på sommaren enligt strikt standardiserade metoder. Sommar- respektive vinterpunktrutter har räknats sedan 1975, i huvudsak i södra Sverige. Standardrutterna räknas också på sommaren (sedan 1996) men täcker hela Sverige. Vintern 2012/2013 räknades 130 000 fåglar av 128 artWe present the results of the Swedish Bird Survey, run by the Department of Biology, Lund University, as a part of the National Monitoring Programme of the Swedish Environmental Protection Agency. The results for 2013 include data from 580 winter point count routes in 2012/2013 (38th winter), of which 295 were carried out during the Christmas/New Year count and 273 summer point count routes (39th

Adverse health manifestations in the hands of vibration exposed carpenters - a cross sectional study

Background: Despite EU regulatory standards, many workers suffer injury as a result of working with hand-held vibrating tools. Our aim of this study was to confirm whether carpenters, a highly exposed group, suffer more injuries to their hands than painters, a group assumed to be less exposed to vibration. Methods: 193 carpenters (participation rate 100%) and 72 painters (participation rate 67%),

Pediatric procedural sedation and analgesia in the emergency department : surveying the current European practice

Procedural sedation and analgesia outside the operating theater have become standard care in managing pain and anxiety in children undergoing diagnostic and therapeutic procedures. The objectives of this study are to describe the current pediatric procedural sedation and analgesia practice patterns in European emergency departments, to perform a needs assessment-like analysis, and to identify barr

Padeliporfin vascular-targeted photodynamic therapy versus active surveillance in men with low-risk prostate cancer (CLIN1001 PCM301) : An open-label, phase 3, randomised controlled trial

Background: Vascular-targeted photodynamic therapy, a novel tissue-preserving treatment for low-risk prostate cancer, has shown favourable safety and efficacy results in single-arm phase 1 and 2 studies. We compared this treatment with the standard of care, active surveillance, in men with low-risk prostate cancer in a phase 3 trial. Methods: This randomised controlled trial was done in 47 Europea

Comprehensive assessment of meteorological conditions and airflow connectivity during HCCT-2010

Abstract. This study presents a comprehensive assessment of the meteorological conditions and atmospheric flow during the Lagrangian-type "Hill Cap Cloud Thuringia 2010" experiment (HCCT-2010), which was performed in September and October 2010 at Mt. Schmücke in the Thuringian Forest, Germany and which used observations at three measurement sites (upwind, in-cloud, and downwind) to study physical

Comparison of MRD monitoring by IG/TR rearrangement and BCR/ABL1 transcript in PH+ pediatric acute lymphoblastic leukemia patients treated with imatinib in the EsPhALL study

Background. In the European Study for Pediatric Ph+ ALL (EsPhALL), a total of 128 patients aged 1 to 18 years diagnosed with ALL and evidence of t(9;22)(q34;q11) received post-Induction Imatinib on top of BFM high risk chemotherapy backbone, either in Good Risk (GR) (after randomization, n=58) or in Poor Risk (PR) (n=70), as defined according to early response to the National induction treatment.

The botanical integrity of wheat products influences the gastric distention and satiety in healthy subjects.

BACKGROUND: Maintenance of the botanical integrity of cereal kernels and the addition of acetic acid (as vinegar) in the product or meal has been shown to lower the postprandial blood glucose and insulin response and to increase satiety. However, the mechanism behind the benefits of acetic acid on blood glucose and satiety is not clear. We hypothesized that the gastric emptying rate could be invol

Development of a FT-NIR model for analysing water content in rapeseed

Lantmännen Lantbruk har i ett projekt tillsammans med Lunds Tekniska Högskola utvecklat en modell för analys av vattenhalt i svenskodlad raps med tekniken Fourier Transform Nära Infraröd (FT-NIR). Kvaliteten i de mätvärden som modellen levererar är mycket lik kvaliteten i den metodik (referensmetodik) som försökte efterliknas när modellen skapades. Även ur ett internationellt perspektiv presterar A FT-NIR (Fourier-Transform Near Infrared) model for moisture content has been developed for whole seeds of Swedish rapeseed (Brassica napus) by the conditions given during the harvest of 2014. Compared to Internal standardized (ISO) method 665, the final model showed very small differences in terms of repeatability and measurement uncertainty even though the measurement time was four times faster

BLOCKS - from place to place

Over the last 20 years the population in large Swedish cities and their suburbs has grown with 25%. This massive population growth has increased the competition in the housing market, which results in people moving more often. The most frequent movers are between 20-30 years old and they move every 6-12 months. With this background the goal was to examine the living situation for these people. Wha

Omplacerad eller utsorterad? - En studie om den rättsliga utvecklingen kring reglerna om omplacering i 7 § andra stycket LAS och omplacering i turordning enligt 22 § fjärde stycket LAS

Lagen om anställningsskydd infördes år 1974 för att trygga anställningen för alla enskilda arbetstagare på den svenska arbetsmarknaden. Tidigare hade arbetstagarnas rättigheter reglerats i kollektivavtal och endast vissa arbetstagares rättigheter var reglerade i lag. Några regler som infördes i 1974 års lag var bland annat saklig grund för uppsägning enigt 7 § LAS. För att saklig grund skulle anseThe Employment Protection Act from 1974 was implemented in to Swedish law as a way to secure the employments of the employees. Before the implementation of the Act, the rights of the employees were regulated in collective agreements. By then there were only some rights regulated in the law. Some of the regulations that were implemented in to the Employment Protection Act was the 7§. The 7 § states

Polymorphism and Expression of CD36 and IRAK3 in Bank Voles

Kan sorkar med mutationer slippa undan infektioner? Sjukdomar är ett av de största hoten som alla levande varelser kan utsättas för. Lyckligtvis har alla djur ett immunförsvar som försöker bekämpa dessa sjukdomar. Detta försvar består av många komponenter vars ritningar finns nedskrivna i DNA. Mutationer, som förändrar DNA, kan leda till olika variationer av en gen, och olika varianter kan påverk

Vad vore jag, utan dina EU-rättsliga krav? - En utredning av förhållandet mellan nationella miljöskatter och EU:s statsstödsregler med särskild fokus på kemikalieskatten

På grund av att miljöskatter kan användas som ett ekonomiskt styrmedel samtidigt som de även tillskrivs ett fiskalt syfte har användningen av dessa i gröna skatteväxlingar blivit populärt hos den svenska lagstiftaren. Att ersätta förlorade intäkter från inkomstskatt med intäkter från miljöskatter kan dock ibland visa sig vara problematiskt, eftersom miljöskatternas styrande effekt medför att de inEnvironmental taxes are often designed to both shift away demand from goods that have a negative impact on the environment, and to generate tax revenue to the public treasury. This makes them appropriate to use in green tax shifts, where the legislator is able to reduce other taxes, e.g. taxes on income, while still being able to maintain overall tax revenue. A green tax shift can however sometime

Model Order Reduction Based on Semidefinite Programming

The main topic of this PhD thesis is complexity reduction of linear time-invariant models. The complexity in such systems is measured by the number of differential equations forming the dynamical system. This number is called the order of the system. Order reduction is typically used as a tool to model complex systems, the simulation of which takes considerable time and/or has overwhelming memory

Social Construction of Technical Aids - Personal Meaning and Interactional Effects of Disability and Assistive Devices in Everyday Life

This thesis concerns the role of disability and assistive devices in everyday life among persons with, for instance, impairments related to mobility (e.g. wheelchair users) and bodily shape and configuration (e.g. dysmelia). Assistive devices are seen as both includators (assisting participation and emancipation) and excludators (limiting participation, restraining empowerment, and stigmatizing).

Brandteknisk riskvärdering av Halmstadtravet

Rapporten är ett examinerande moment i kursen Brandteknisk riskvärdering. Syftet med rapporten är att utvärdera personsäkerheten vid brand för besökarna på Halmstadtravet och ge förslag på eventuella förbättringar. Syftet är även att studenterna ska tränas i sin ingenjörsmässiga förmåga. I byggnaden som utvärderas finns bland annat restaurang, kök, sittplatsläktare och caféverksamhet. Det redogörThe report is an examination element of the course Brandteknisk riskvärdering. The purpose of the report is to evaluate human safety of visitors in case of fire at the racetrack Halmstadtravet and suggest possible solutions if the human safety is deemed insufficient. The purpose is also to train the students in their engineering capability. The method is to choose several fire scenarios that chal

Evaluation of systems for piperun installation

The purpose of this thesis project was to analyse and evaluate different systems for installation of piperun in ceilings. Main focus lay on how the systems influence the installer from an ergonomic point of view as well as productivity in terms of installation time. Several studies have been performed during this project using a variety of methods such as observations, interviews, questionnaires a