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Islet dysfunction is central to the development and progression of type 2 diabetes (T2D). Epigenetic modifications are essential for establishing and maintaining cell identity and function in normal circumstances. Exposure to adverse environmental factors may alter the epigenome, and result in changes of gene expression and the resulting phenotype. The aim of this thesis was to analyze DNA methyla

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In 2011, the UN published a framework called the United Nations Guiding Principles on Business and Human Rights (UNGP) and it has been viewed as a first of its kind, by being a global standard of principles that aims to prevent and address risks of human rights violations concerning corporate activities. The framework was ratified by all UN member states and received support from other non-state a