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The efficacy and safety of an advanced category recombinant antihaemophilic factor produced by a plasma- and albumin-free method (rAHF-PFM) was studied in 111 previously treated subjects with haemophilia A. The study comprised a randomized, double-blinded, crossover pharmacokinetic comparison of rAHF-PFM and RECOMBINATE rAHF (R-FVIII); prophylaxis (three to four times per week with 25-40 IU kg(-1)
Adult patients with acute lymphoblastic leukaemia ( ALL) have been treated according to national protocols in Sweden since 1986. Stem cell transplantation (SCT) has been recommended in first remission for patients with risk factors for relapse, and for standard risk patients only after relapse. In this retrospective study, the results of autologous and allogeneic SCT in these populations were eval
For unknown reasons, there is a greater increase in the risk for cardiovascular complications in diabetic women than in diabetic men. Our aim was to study gender-related differences in the mechanical properties of the great arteries in patients with insulin-dependent diabetes mellitus (IDDM) but free from known cardiovascular and cerebrovascular complications. We measured arterial stiffness (beta,
Background: Uveal melanoma is the most common primary intraocular malignancy in adults. Despite successful control of the primary tumor, metastatic disease will ultimately develop in approximately 50% of patients, with the liver being the most common site for metastases. The median survival for patients with liver metastases is between 6 and 12 months, and no treatment has in randomized trials eve
Background: We evaluated the efficacy and safety of the aromatase inhibitor exemestane in patients with advanced, persistent or recurrent endometrial carcinoma. Methods: We performed an open-label one-arm, two-stage, phase II study of 25 mg of oral exemestane in 51 patients with advanced (FIGO stage III-IV) or relapsed endometrioid endometrial cancer. Patients were stratified into subsets of estro
The purpose of this phase II randomized trial was to evaluate the effect and safety of interferon-2a (IFN) in combination with extended dosing rituximab in patients with symptomatic, advanced indolent lymphoma responding to a standard single course of rituximab. Totally 123 patients were treated with rituximab 375mg/m2 once weekly for 4 weeks leading to 14 complete response (CR; 11%), 56 partial r
Objectives. Studies have suggested a correlation between untreated celiac disease and risk for other autoimmune diseases. We investigated the prevalence of thyroid autoimmunity in 12-year-old children (i) with symptomatic celiac disease diagnosed and treated with a gluten-free diet, (ii) with screening-detected untreated celiac disease, and (iii) without celiac disease. Methods. Blood samples from
Aim: The purpose of this study was to investigate the relationship between maximum oxygen uptake (VO2PEAK) and body fat in young children on a population-based level. Methods: Participants were 586 children (311 boys and 275 girls) aged 6.8 +/- 0.4 years, recruited from a population-based cohort. VO2PEAK was measured by indirect calorimetry during a maximal exercise test. Percent body fat (BF%) wa
Bibl io tekss tyrel sen Närvarande Ledamöter Olov Sterner dekanus, naturvetenskapliga fakulteten, ordförande Björn Bergenståhl professor, Lunds Tekniska Högskola Samuel Byrskog prodekan, humanistiska och teologiska fakulteterna Gudrun Edgren professor, medicinska fakulteten Tomas Hellström professor, Ekonomihögskolan Jan-Åke Nilsson professor, naturvetenskapliga fakulteten Vilhelm Persson prefekt,
https://www.lub.lu.se/sites/lub.lu.se/files/protokoll_bs_20150526_1.pdf - 2026-07-12
This master’s thesis maps and compares local literary networks within UNESCO’s Cities of Literature, with the aim of understanding how such networks are structured, what their functions are and how they are controlled and developed. Drawing on concepts from social network analysis and Bourdieu’s theories of social fields, capital and habitus, the study combines quantitative and qualitative methods
The morphology and function of the arteries can be directly measured using different established methods. This prospective cohort study aimed to translate 2 of these, aortic pulse wave velocity (aPWV) and carotid intima–media thickness (cIMT), into a combined Vascular Aging Index (VAI) and then evaluate the predictive power of aPWV, cIMT, and VAI. Patients (n = 2718) were included from the cardiov
Vetenskapsteori i samhällsvetenskaperna, SGR002F SGR002F 2023-08-28 - 2024-01-14 v 35-2 v 35-v 2 Vetenskapsteori i samhällsvetenskaperna, SGR002F Tid Undervisningstyp Grupp Lokaler Lärare Kommentar v 43 Fre 2023-10-27 13:15 - 14:15 Introduktion SGR002F G:a Kirurgen 148 (Hus R 148), Helle Rydström Course introduction. v 44 Mån 2023-10-30 10:00 - 12:00 Föreläsning SGR002F G:a Kirurgen 148 (Hus R 148
- and more opportunities within or via NordIAS The NordIAS fellow exchange programme aims to promote networking and strengthen academic dialogue between participating institutes and researchers. For the individual researchers, the programme offers opportunities for short, "hassle free", sabbaticals. The NordIAS fellow exchange programme is an opportunity for researchers at one of the eight Institu
https://www.pi.lu.se/en/international-exchanges/nordias/nordias-fellow-exchange-programme - 2026-07-11
https://www.real.lu.se/en/alexandra-kjellman - 2026-07-11
https://www.ehl.lu.se/hj-holm - 2026-07-11
https://www.intramed.lu.se/en/hakan-goransson - 2026-07-11
Background: The emergence of highly active novel agents has led some to question the role of autologous haematopoietic stem-cell transplantation (HSCT) and subsequent consolidation therapy in newly diagnosed multiple myeloma. We therefore compared autologous HSCT with bortezomib–melphalan–prednisone (VMP) as intensification therapy, and bortezomib–lenalidomide–dexamethasone (VRD) consolidation the
Background: Ghrelin derives from endocrine cells (A-like cells) in the stomach (mainly the oxyntic mucosa). Its concentration in the circulation increases during fasting and decreases upon re-feeding. This has fostered the notion that the absence of food in the upper gastrointestinal (GI) tract stimulates the secretion of ghrelin. The purpose of the present study was to determine the concentration
Popular Abstract in Swedish Alla levande organismer består av celler som tillsammans med molekyler generellt kallade extracellulär matrix bildar en vävnad. Celler innehåller fyra huvudgrupper av byggstenar: socker, fettsyror, aminosyror och nukleotider, vilka i tur och ordning bildar kolhydrater, fetter, proteiner och nukleinsyror. I vävnaderna pågår en ständig omsättning av byggstenarna och molek
