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Medicinska fakulteten, Lund, i Almedalen 2025

Medicinska fakulteten 2025Att förebygga folksjukdomar med precisionsmedicin25 juni 2025 14:00 till 14:45 | SeminariumNu kan sjukvården hitta de personer som har störst risk för bland annat hjärtkärlsjukdom med hjälp av forskningen inom precisionsmedicin. Detta skapar vinster för såväl individen som samhället.Som några av de första i världen jobbar Region Skåne och Lunds universitet tillsammans för

https://www.medicin.lu.se/samverkan/popularvetenskapliga-arrangemang/medicinska-fakulteten-lund-i-almedalen-2025 - 2026-05-16

Lund Seminar Szewc

Lund_Seminar_Szewc Machine Learning for Monte Carlo simulators in collider physics Lund University, 13/05/25 Manuel Szewc https://uchep.gitlab.io/mlhad-docs/ https://www.google.com/url?q=https://uchep.gitlab.io/mlhad-docs/&sa=D&source=editors&ust=1747230305868480&usg=AOvVaw0zKNVwxTEa-8H_8uPNdnbv The MLHAD team Benoit Assi, Christian Bierlich, Phil Ilten, Tony Menzo, Stephen Mrenna, Manuel Szewc, M

https://www.particle-nuclear.lu.se/sites/particle-nuclear.lu.se/files/2025-05/Lund_Seminar_Szewc.pdf - 2026-05-16

Mven05 prel. schema vt17 v.1 x

Schema MVEN05 Styrmedel för förebyggande miljöskydd VT2017 Läsning för lektionerna ges i modulbeskrivningarna Lokal: Mossen Öster, Ekologihuset, se karta (undantag 1 febr då ni är i ”Liganden” i Biologihuset) Datum och tid Aktivitet Lärare Lokal Modul I: Styrning och styrmedel 16 jan 10-15 (på Internationella miljöinstitutet) 17 jan 10-13 18 jan 10-13 20 jan 10-13 23-24 jan Kursintroduktion och fö

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/mven05_prel._schema_vt17_v.1_x.pdf - 2026-05-16

Treatment outcomes of childhood PICALM::MLLT10 acute leukaemias

The prognostic impact of PICALM::MLLT10 status in childhood leukaemia is not well described. Ten International Berlin Frankfurt Münster-affiliated study groups and the Children's Oncology Group collaborated in this multicentre retrospective study. The presence of the PICALM::MLLT10 fusion gene was confirmed by fluorescence in situ hybridization and/or RNA sequencing at participating sites. Ninety-

Selection of random RNA fragments as method for searching for a site of regulation of translation of E. coli streptomycin mRNA by ribosomal protein S7

In E. coli cells ribosomal small subunit biogenesis is regulated by RNA-protein interactions involving protein S7. S7 initiates the subunit assembly interacting with 16S rRNA. During shift-down of rRNA synthesis level, free S7 inhibits self-translation by interacting with 96 nucleotides long specific region of streptomycin (str) mRNA between cistrons S12 and S7 (intercistron). Many bacteria do not

Defining new reference intervals for serum free light chains in individuals with chronic kidney disease : Results of the iStopMM study

Serum free light chain (FLC) concentration is greatly affected by kidney function. Using a large prospective population-based cohort, we aimed to establish a reference interval for FLCs in persons with chronic kidney disease (CKD). A total of 75422 participants of the iStopMM study were screened with serum FLC, serum protein electrophoresis and immunofixation. Estimated glomerular filtration rate

Aerobic fitness in prepubertal children according to level of body fat

Aim: The purpose of this study was to investigate the relationship between maximum oxygen uptake (VO2PEAK) and body fat in young children on a population-based level. Methods: Participants were 586 children (311 boys and 275 girls) aged 6.8 +/- 0.4 years, recruited from a population-based cohort. VO2PEAK was measured by indirect calorimetry during a maximal exercise test. Percent body fat (BF%) wa

Autologous and allogeneic stem cell transplantation in adult ALL: the Swedish Adult ALL Group experience

Adult patients with acute lymphoblastic leukaemia ( ALL) have been treated according to national protocols in Sweden since 1986. Stem cell transplantation (SCT) has been recommended in first remission for patients with risk factors for relapse, and for standard risk patients only after relapse. In this retrospective study, the results of autologous and allogeneic SCT in these populations were eval

Genomic Allergen Rapid Detection In-House Validation—A Proof of Concept

Chemical sensitization is an adverse immunologic response to chemical substances, inducing hypersensitivity in exposed individuals. Identifying chemical sensitizers is of great importance for chemical, pharmaceutical and cosmetic industry, in order to prevent the use of sensitizers in consumer products. Historically, chemical sensitizers have been assessed mainly by in vivo methods, however, recen

Real world data on prognostic factors and treatment in peripheral T-cell lymphomas: a study from the Swedish Lymphoma Registry.

Peripheral T-cell Lymphomas (PTCLs) are rare lymphomas with mostly poor outcome with current treatment. Addition of etoposide to CHOP and up-front consolidation with autologous stem cell transplantation (autoSCT) have shown promising results, but have never been tested in randomized trials. As a complement to retrospective analyses of clinical trials, we aimed at analyzing prognostic factors and o

Immobilization of thermostable beta-glucosidase variants on acrylic supports for biocatalytic processes in hot water

Two variants of the thermostable beta-glucosidase TnBgl1A (wt and N221S/P342L) from Thermotoga neapolitana were immobilized on acrylic supports (Eupergit (R) C, Eupergit (R) C250L, and cryogel) and evaluated at conditions close to the boiling point of water. Thermo-gravimetric analysis showed the supports to be stable <250 degrees C. Both wt and N221S/P342L were covalently bound to oxirane-groups

The applicability of the WHO classification in paediatric AML. A NOPHO-AML study

The World Health Organization (WHO) classification of myeloid leukaemia was revised in 2008. It incorporates newly recognized entities and emphasizes the pivotal role of cytogenetic abnormalities. The aim of this study was to evaluate the usability of the WHO classification when applied to a large population-based paediatric acute myeloid leukaemia (AML) cohort. We included children diagnosed with

Clinical evaluation of an advanced category antihaemophilic factor prepared using a plasma/albumin-free method: pharmacokinetics, efficacy, and safety in previously treated patients with haemophilia A

The efficacy and safety of an advanced category recombinant antihaemophilic factor produced by a plasma- and albumin-free method (rAHF-PFM) was studied in 111 previously treated subjects with haemophilia A. The study comprised a randomized, double-blinded, crossover pharmacokinetic comparison of rAHF-PFM and RECOMBINATE rAHF (R-FVIII); prophylaxis (three to four times per week with 25-40 IU kg(-1)

Increased arterial stiffness in women, but not in men, with IDDM

For unknown reasons, there is a greater increase in the risk for cardiovascular complications in diabetic women than in diabetic men. Our aim was to study gender-related differences in the mechanical properties of the great arteries in patients with insulin-dependent diabetes mellitus (IDDM) but free from known cardiovascular and cerebrovascular complications. We measured arterial stiffness (beta,

Examestane in advanced or recurrent endometrial carcinoma: a prospective phase II study by the Nordic Society of Gynecologic Oncology (NSGO)

Background: We evaluated the efficacy and safety of the aromatase inhibitor exemestane in patients with advanced, persistent or recurrent endometrial carcinoma. Methods: We performed an open-label one-arm, two-stage, phase II study of 25 mg of oral exemestane in 51 patients with advanced (FIGO stage III-IV) or relapsed endometrioid endometrial cancer. Patients were stratified into subsets of estro

Prevalence of thyroid autoimmunity in children with celiac disease compared to healthy 12-year olds.

Objectives. Studies have suggested a correlation between untreated celiac disease and risk for other autoimmune diseases. We investigated the prevalence of thyroid autoimmunity in 12-year-old children (i) with symptomatic celiac disease diagnosed and treated with a gluten-free diet, (ii) with screening-detected untreated celiac disease, and (iii) without celiac disease. Methods. Blood samples from