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Proteomics and Phosphoproteomics Analysis of Parental and Cisplatin-Resistant Ovarian Cancer Cell Lines Treated with C26A6 and Volasertib

Mot smartare cellgiftsbehandling: Att förebygga behandlingsresistens vid äggstockscancer Äggstockscancer är den dödligaste gynekologiska cancertypen och kräver alltför många liv eftersom tumörer ofta blir resistenta mot behandling – särskilt mot cisplatin, vårt främsta försvar. För att rädda fler liv måste vi förstå hur denna resistens utvecklas och hur vi kan överlista den. I mitt examensarbete Ovarian cancer is the deadliest gynaecologic malignancy, with most patients diagnosed at an advanced stage and facing poor long-term survival. Resistance to cisplatin-based chemotherapy is a major clinical obstacle, yet its proteomic drivers remain poorly defined. In this study, I applied data-independent acquisition mass spectrometry with DIA-NN data processing to analyse one parental and two cis

English Influence in Swedish Advertising: A Comparative Study of Recent English Loanwords and Swedish-English Code-Switching in the Printed and Online Versions of Five Magazines and Newspapers

This paper investigates to what extent Swedish-English code-switching and recent English loanwords occur in the printed and online versions of five newspapers and magazines. The newspapers and magazines that were included are Aftonbladet, Amelia, Elle, Café, and Helsingborgs Dagblad. The study shows that English was the most common in the printed media, while the hypothesis was that it would be mo

Perdeuteration of Biological Macromolecules: A Case Study of Human Carbonic Anhydrases

Deuterated biomolecules - where hydrogen atoms (H) are exchanged to its isotope deuterium (D) - are essential for biological experiments in neutron scattering, but they are not readily available. In neutron scattering, D has a strong positive coherent scattering length (6.67 fm) in comparison with the negative scattering length of H (-3.74 fm). These different characteristics of neutrons to D and Deuterated biomolecules - where hydrogen atoms (H) are exchanged to its isotope deuterium (D) - are essential for biological experiments in neutron scattering, but they are not readily available. In neutron scattering, D has a strong positive coherent scattering length (6.67 fm) in comparison with the negative scattering length of H (-3.74 fm). These different characteristics of neutrons to D and

2025 Spring meeting

The COMPUTE spring meeting 2025 will take place on Monday the 28th of April 2025. The theme is "Development of Scientific Software". The event is aimed atall who write code to do their research and want to become better at itall who use code to do their research and want to learn more about where this code comes from and how it might be improved.Program 9:45 - 10:15Fika before lecture room MH:Ries

https://www.compute.lu.se/other-activities/2025-spring-meeting - 2026-05-29

Practical information

Practical information | Vattenhallen Science Center Skip to main content This site uses cookies to enhance the user experience. By continuing to use the site you agree that cookies are used according to our Cookie Policy (on the website of LTH) . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These cookies do not store any persona

https://www.vattenhallen.lu.se/vattenhallen-english/visit-us/practical-information/ - 2026-05-30

Inhibition of IL-4Rα reduces CCL26 in bronchial epithelial cells from COPD patients

Background Anti-interleukin (IL)-4Rα monoclonal antibodies (mAb) improve lung function and decreasethe number of exacerbations in patients with COPD type (T) 2 inflammation. However, the involvement ofearly innate immune responses underlying these treatment effects is not well known. We sought tounderstand the effect and mechanisms of IL-4Rα mAb treatment on bronchial epithelial cells (BECs) fromCBackgroundAnti-IL-4Rα monoclonal antibodies (mAb) improve lung function and decrease the number of exacerbations in patients with COPD type (T) 2 inflammation. However, the involvement of early innate immune responses underlying these treatment effects is not well known. We sought to understand the effect and mechanisms of IL-4Rα mAb treatment on bronchial epithelial cells from COPD patients under

No title

Raoul Wallenberg Institute of Human Rights and Humanitarian Law #198E2, Street 51, corner Street 370, BKK1, Chamkarmon, Phnom Penh, Cambodia | Phone +85598 531 405 CAMBODIA Call for Applications: Regional Human Rights Research Initiative 2018 As part of its Capacity Development Programme in Cambodia 2013-2019, the Raoul Wallenberg Institute of Human Rights and Humanitarian Law (RWI) hereby calls f

https://rwi.lu.se/app/uploads/2018/01/Invitation-Call-for-Application-2018-Cambodia.pdf - 2026-05-31

A combined experimental and theoretical study of uranium polyhydrides with new evidence for the large complex UH4(H-2)(6)

Several monouranium and diuranium polyhydride molecules were investigated using quantum chemical methods. The infrared spectra of uranium and hydrogen reaction products in condensed neon and pure hydrogen were measured and compared with previous argon matrix frequencies. The calculated molecular structures and vibrational frequencies were used to identify the species present in the matrix. Major n

β-Mannan degradation by gut bacteria - Characterization of β-mannanases from families GH5 and GH26

Popular Abstract in Swedish Människan lever inte bara själv, utan tillsammans med en mängd bakterier som lever i kroppen. Större delen av dessa lever i tjocktarmen. Dessa organismer är viktiga för vår hälsa. De stimulerar immunförsvaret, sänker pH i tarmen och gör det ogynnsamt för sjukdomsframkallande bakterier att växa till. Bakterierna lever i symbios med oss och med varandra. Förändringar i taThe human gut flora is important for our well-being. The gut bacteria are able to degrade and metabolize complex carbohydrates. Examples of such carbohydrates are β-mannans. β-Mannans consist of a backbone of β-1,4-linked mannose units and are present in e.g. the endosperm of legumes such as guar or carob. The composition of the β-mannan varies with the plant source. Carob and guar β-mannans are s

Preparation of highly multiplexed small RNA sequencing libraries

MicroRNAs (miRNAs) are ~22-nucleotide-long small non-coding RNAs that regulate the expression of protein-coding genes by base pairing to partially complementary target sites, preferentially located in the 3´ untranslated region (UTR) of target mRNAs. The expression and function of miRNAs have been extensively studied in human disease, as well as the possibility of using these molecules as biomarke

Tidplan DESS 2024-2025 250422

Tidplan-DESS-Rigg_250422.xlsx C:\Hardeberga Energiteknik AB\Kunder\Ecergy\P2308 LTH HP-rigg\04 Planering\Tidplan-DESS-Rigg_250422.xlsx DESS-Rigg - Återställning 2024-2025 Anders Dahl 2025-04-22 Projektresurser LTH Jens, Christer, Anders O Anm: "Driftsättning-kall" pausas för Montage kassetter samt tryckkärl (tunga lyft) Ecergy Anders Dahl Afry Tara Sabzevari Leverantörer Bricon, APQ-el, Rörläggare

https://www.energy.lth.se/sv/sites/energy.lth.se.sv/files/2025-05/Tidplan_DESS_2024-2025_250422.pdf - 2026-05-30

Countercurrent Distribution of Lymphocytes from Human Peripheral Blood in an Aqueous Two-Phase System : I. Separation into Subsets of Lymphocytes Bearing Distinctive Markers’

Lymphocytes from human peripheral blood have been separated by countercurrent distribution in a charged aqueous two-phase system composed of Dextran T 500 and polyethylene glycol 6000 with a cell yield of 59–88% and viability above 90%. A highly reproducible partition pattern was seen with four distinct peaks. Lymphocytes with surface membrane immunoglobulin (SmIg) were located in the first part o

Influence of the mannan binding module of beta-mannanase CfMan26A in the hydrolysis of mannan

Hemicellulose is next to cellulose the most abundant polysaccharide on earth and as such an important renewable resource. Mannans are the major hemicellulose in so:ftwodd and are found as storage polysaccharide in various plants. -mannanases are the main mannan degrading enzymes. In this work the -1,4-mannanase from the soilliving bacteria Cellulosamas Jimi was studied and special focus was put on