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Water services with independent providers in peri-urban Maputo: Challenges and opportunities for long-term development

Water service delivery to most residents of peri-urban areas of greater Maputo depends largely on alternative service providers. mostly in the form of small-scale independent providers (SSIPs). This paper discusses the present and long-term challenges facing SSIPs in supplying quality water of sufficient quantity in peri-Urban Maputo and possible human health risks associated with the consumption

Aquaporin-3a Dysfunction Impairs Osmoadaptation in Post-Activated Marine Fish Spermatozoa

Spermatozoon volume regulation is an essential determinant of male fertility competence in mammals and oviparous fishes. In mammals, aquaporin water channels (AQP3, -7 and -8) have been suggested to play a role in spermatozoon cell volume regulatory responses in the hypotonic female oviduct. In contrast, the ejaculated spermatozoa of marine teleosts, such as the gilthead seabream (Sparus aurata),

Health-related quality of life and supportive care needs in young adult cancer survivors—a longitudinal population-based study

Purpose: To examine health-related quality of life (HRQoL) and supportive care needs among young adult (YA) cancer survivors up to 3 years post-diagnosis. Methods: A national cohort of individuals diagnosed at 18–39 years with breast, cervical, ovarian, or testicular cancer, lymphoma or brain tumor was approached with surveys at 1.5 (n = 1010, response rate 67%) and 3 (n = 722) years post-diagnosi

Resveratrol mediated cell death in cigarette smoke transformed breast epithelial cells is through induction of p21Waf1/Cip1 and inhibition of long patch base excision repair pathway

Cigarette smoking is a key factor for the development and progression of different cancers including mammary tumor in women. Resveratrol (Res) is a promising natural chemotherapeutic agent that regulates many cellular targets including p21, a cip/kip family of cyclin kinase inhibitors involved in DNA damage-induced cell cycle arrest and blocking of DNA replication and repair. We have recently show

Models of natural pest control : Towards predictions across agricultural landscapes

Natural control of invertebrate crop pests has the potential to complement or replace conventional insecticide-based practices, but its mainstream application is hampered by predictive unreliability across agroecosystems. Inconsistent responses of natural pest control to changes in landscape characteristics have been attributed to ecological complexity and system-specific conditions. Here, we revi

Exceptional fossil preservation: implications for palaeobiology and taphonomy

Although fossils are relatively common in some sedimentary deposits, the majority consists of fragmented or distorted skeletal hard parts (such as shell and bones). However, in rare cases, special burial and diagenetic conditions have allowed a greater portion of the original anatomy to be incorporated into the fossil record. This exceptional type of preservation is characterised by the retention

On the use of prostate-specific antigen for screening of prostate cancer in European Randomised Study for Screening of Prostate Cancer

Prostate-specific antigen (PSA) has been the main drive for early detection of prostate cancer (PCa), including in population-based screening as in the European Randomised Study for Screening of Prostate Cancer (ERSPC). The specificity of PSA to indicate men with biopsy detectable prostate cancer can be improved by adding information obtained by new biomarkers, such as PSA isoforms. This improveme

Savouring the sea: Production and consumption of future seaweed foods

Current food systems pose one of the greatest health and environmental challenges of the21st century. A systemic shift in the food sector can be accelerated by technologies and innovations,such as seaweed food applications. However, introducing and expanding seaweed as a food resourceinto Western markets comes with several challenges.These challenges include its microbial, chemical, and sensory qu

Searches for New Physics Using Innovative Data Acquisition, Analysis, and Compression Techniques

När forskare blickar ut i universum ser de överallt spåren av en stor mängd osynlig massa. Massan finns där men det går inte att se den. Ungefär 80% av all massa i universum beräknas bestå av denna "mörka materia". Det är som att mänskligheten står på stranden och blickar ut över havet utan att veta vad vatten är. I partikelfysik studeras universums minsta beståndsdelar, elementarpartiklarna, för The high event rate delivered by the Large Hadron Collider (LHC) provides experiments with opportunities for new discoveries as well as challenges related to the large amounts of data recorded. Overcoming this requires innovative techniques in the three topics of this thesis: Data acquisition, data analysis, and data compression.In the data taking period of 2015-2018, the ATLAS experiment received

Clinical progression, disease severity, and mortality among adults hospitalized with COVID-19 caused by the Omicron and Delta SARS-CoV-2 variants : A population-based, matched cohort study

BACKGROUND: To compare the intrinsic virulence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) omicron variant with the delta variant in hospitalized adults with coronavirus disease 2019 (COVID-19).METHODS: All adults hospitalized in the Capital Region of Copenhagen with a positive reverse transcription polymerase chain reaction test for SARS-CoV-2 and an available variant dete

Ecological factors influence timing of departures in nocturnally migrating songbirds at Falsterbo, Sweden

Most songbirds depart from stopover sites after sunset and migrate during the night. Several recent studies have reported larger variation in departure time than previously thought; yet, it is still unclear which factors govern departure timing. We investigated the departure timing of four species of nocturnally migrating songbirds using an automated radiotelemetry system at Falsterbo peninsula in

Parametric Analysis of the Effect of Pilot Quantity, Combustion Phasing and EGR on Efficiencies of a Gasoline PPC Light-Duty Engine

In this paper, a parametric analysis on the main engine calibration parameters applied on gasoline Partially Premixed Combustion (PPC) is performed. Theoretically, the PPC concept permits to improve both the engine efficiencies and the NOx-soot trade-off simultaneously compared to the conventional diesel combustion. This work is based on the design of experiments (DoE), statistical approach, and i

Cerebrospinal fluid Alzheimer's disease biomarkers across the spectrum of lewy body diseases : Results from a large multicenter cohort

Background: Concomitant Alzheimer's disease (AD) pathology is observed in Lewy body diseases (LBD), but the clinical impact is unknown. Only a few biomarker studies in LBD exist and have included small cohorts from single centers. Objective: We aimed to evaluate the prevalence of abnormal cerebrospinal fluid (CSF) AD biomarkers across the spectrum of LBD in a large multicenter cohort and to assess

Gastric bypass in the pig increases GIP levels and decreases active GLP-1 levels

Gastric bypass surgery results in remission of type 2 diabetes in the majority of patients. The incretin hormones glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) have been implicated in the observed remission. Most knowledge so far has been generated in obese subjects. To isolate the surgical effects of gastric bypass on metabolism and hormone responses from

Jet-jet interaction in multiple injections: A large-eddy simulation study

This paper reports on studies of multiple-injection strategies of gaseous fuel in a model combustion chamber and the role of jet-jet interactions on the mixing processes in the chamber using large-eddy simulation (LES). A high-pressure non-reacting gas flow injected through a jet with a nozzle diameter of 1.35 mm into a quiescent inert air environment is considered. First, we validate the method a

Microbial growth and carbon use efficiency in soil : Links to fungal-bacterial dominance, SOC-quality and stoichiometry

Microbial decomposers are responsible for the breakdown of organic matter (OM) and thus regulate soil carbon (C) stocks. During the decomposition of OM, microorganisms can use the assimilated C for biomass production or respire it as CO2, and the fraction of growth to total assimilation defines the microbial carbon-use efficiency (CUE). As such, CUE has direct consequences for how microbial decomp

Quantitative flow ratio for immediate assessment of nonculprit lesions in patients with ST-segment elevation myocardial infarction—An iSTEMI substudy

Objectives: We evaluated the diagnostic performance of quantitative flow ratio (QFR) assessment of nonculprit lesions (NCLs) based on acute setting angiograms obtained in patients with ST-segment elevation myocardial infarction (STEMI) with QFR, fractional flow reserve (FFR), and instantaneous wave-free ratio (iFR) in the staged setting as reference. Background: QFR is an angiography-based approac

From combating to supporting pop music. The paradox of municipal music education in Sweden 1940 to 2000 : ESA2009 – 9th Conference of European Sociological Associationin the University of Lisbon on Sept. 2nd-5th, 2009

In 1997 Sweden was the third biggest exporter of popular music in the world. This astonishing fact has often been explained as being the result of the large investments in municipal music schools that took place in Sweden from 1940. The explanation holds an interesting paradox. Most municipal music schools began with the aim to teach young people appreciate more valuable music (i.e. classical) tha

Comparison of four clinical risk scores in comatose patients after out-of-hospital cardiac arrest

Background and aims: Several different scoring systems for early risk stratification after out-of-hospital cardiac arrest have been developed, but few have been validated in large datasets. The aim of the present study was to compare the well-validated Out-of-hospital Cardiac Arrest (OHCA) and Cardiac Arrest Hospital Prognosis (CAHP)-scores to the less complex MIRACLE2- and Target Temperature Mana