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Screening women for lower genital tract infection with Chlamydia trachomatis is important in the prevention of pelvic inflammatory disease, ectopic pregnancy and infertility. This systematic review aims to state clearly which of the available diagnostic tests for the detection of C. trachomatis would be most effective in terms of clinical effectiveness. The review included all studies published fr
Background: Current consumption levels of animal products (APs) are unsustainable but measures to reduce their consumption are lacking. Simultaneously, APs are widely perceived as healthy which hinders their substitution with other foods. The AP-industry might influence AP consumption as they have the necessary financial means, the interest and the organizational capacity. Objective: To investiga
Epidemiologic studies have reported that moderate alcohol consumption is inversely associated with the risk of renal cancer. However, there is no information available on the associations in renal cancer subsites. From 1992 through to 2010, 477,325 men and women in the European Prospective Investigation into Cancer and Nutrition cohort were followed for incident renal cancers (n=931). Baseline and
The aim of this study was to determine the threshold of fracture probability at which interventions become cost-effective. We modeled the effects of a treatment costing $500/year, given for 5 years, that decreased the risk of all osteoporotic fractures by 35%, followed by a waning of effect for 5 years. Sensitivity analyses included a range of effectiveness (10%-50%) and a range of intervention co
ABSTRACT Calcareous sandy grasslands are among the most threatened habitats in Europe, primarily because of abandonment, acidification, eutrophication and fragmentation. Much of the biodiversity found in calcareous sandy grasslands depend on the availability of calcareous sand in the topsoil layer. As this sand is naturally depleted of CaCO3 heavy disturbances such as erosion or use of military
With the book The Theory of the Growth of the Firm, published in 1959, takes the researcher Edith Penrose the first step towards what will later be known as the resource based view. Many scholars have since taken up where Penrose left and has further developed the approach to something that can now be described as almost a philosophy. Today is the resource based view synonymous with an internal fo
Abstract Title: Ethanol for Scania’s future – A scenario based analysis Authors: Anna Hansson and Julia Persson Tutors: Annette Cerne – Department of Business Administration, Lund University Jonas Holmborn – Head of Advanced Combustion, Engine Development, Scania Lennart Thörnqvist – Department of Energy Sciences, Faculty of Engineering, Lund University Problem: Oil-based products are the dominati
Compulsory licensing is used to prevent the owner of an intellectual property right from refusing to exploit that right in a country or from being the sole provider of a product by forcing him to permit competition from other producers', subject only to their payment of a reasonable royalty or licence fee. When a compulsory license is used to remedy an abuse of competition law, issues of confl
Packaging is one of the logistics areas where there often is potential and even a demand for improvements. An increase in environmental awareness among the population in the European Union (EU) has generated a demand for changes in packaging, which has led to stricter rules and regulations. Knowledge about what regulations are present and what may be expected in the future is crucial in the formin
Atmospheric aerosol samples from a boreal forest (Hyytiala, April 2007), a rural site in Hungary (K-puszta, summer 2008), a polluted rural area in Italy (San Pietro Capofiume, Po Valley, April 2008), a moderately polluted rural site in Germany located on a meadow (Melpitz, May 2008), a natural park in Spain (Montseny, March 2009) and two urban background locations (Zurich, December 2008, and Barce
The aim of this multicenter study was to investigate whether a computer-assisted diagnosis (CAD) system could improve performance and reduce interobserver variation in bone-scan interpretations of the presence or absence of bone metastases. Methods: The whole-body bone scans (anterior and posterior views) of 59 patients with breast or prostate cancer who had undergone scintigraphy for suspected bo
IntroductionDuring 2008, the oil price climbed from one peak to the next. Despite the fact that high grain and sugar prices – the main feed stocks for bioethanol plant – are currently causing a slow down in the realisation of bioethanol projects, the interest for renewable fuels is still increasing. In the Nordic countries, Sweden and Finland are leading the development of bioethanol production, w
Background Accurate estimation of prognosis in multimorbid hospital patients could improve quality of care. This study aims to determine the relative importance and added value of a performance-based activities of daily living (ADL) measure with regard to mortality prediction. Methods 200 inpatients, aged over 60 years, were recruited at the Department of General Internal Medicine at a tertiary un
Background: To date, the estimated radiation-absorbed dose to organs and tissues in patients undergoing diagnostic examinations in nuclear medicine is derived via calculations based on models of the human body and the biokinetic behaviour of the radiopharmaceutical. An internal dosimetry computer program, IDAC-Dose2.1, was developed based on the International Commission on Radiological Protection
Microorganisms in soil are commonly limited by available substrate, and removing the limitation will increase activity and growth, with predictable dynamics in growth. The initial phase with a lag period (λ) will usually be followed by exponential growth (also called log phase, with growth rate μ). These two growth phases may be differently affected by environmental conditions, like temperature an
Background: Somali women suffer from one of the highest maternal mortality rates in the world. Somalia characterises a specific low-income country situation with a mix of newly urbanized and nomadic culture combined with a frail health care infrastructure set in a post-conflict era. Very little is known about the effects that these contextual factors can have on maternal mortality. Objectives: To
Recent studies indicate that selective noradrenergic (atomoxetine) and serotonergic (citalopram) reuptake inhibitors may improve response inhibition in selected patients with Parkinson's disease, restoring behavioral performance and brain activity. We reassessed the behavioral efficacy of these drugs in a larger cohort and developed predictive models to identify patient responders. We used a doubl
OBJECTIVES: To identify variables associated with longitudinal change in meniscal extrusion, which might be used as possible targets for knee osteoarthritis (KOA) prevention. METHODS: In a high-risk population of middle-aged overweight women, meniscal extrusion was assessed with magnetic resonance imaging (1.5 T, coronal proton density, in-plane resolution 0.5 mm2, Sante DICOM Editor) at baseline
PURPOSE: We assessed the associations between population-based polygenic risk scores (PRS) for breast (BC) or epithelial ovarian cancer (EOC) with cancer risks for BRCA1 and BRCA2 pathogenic variant carriers. METHODS: Retrospective cohort data on 18,935 BRCA1 and 12,339 BRCA2 female pathogenic variant carriers of European ancestry were available. Three versions of a 313 single-nucleotide polymorph
In October 2017, the EU Commission announced a consultation on supplementary protection certificates (SPCs) and research exemptions, including Bolar-type provisions. The consultation will provide valuable input for the Commission when preparing an evaluation of the current EU legislation, and any future policy proposals on SPCs and patent exemptions, including the assessment of the impact of diffe
