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Retired, affiliated researcher Contact details Email: lars [dot] gislen [at] fysik [dot] lu [dot] se Mobile: +46 72 552 95 60Organisation Particle and nuclear physics Service point: 14 WebpageLars Gisléns profile in Lund University research portalHome address:Dala 7163 SE-24297 Hörby SwedenPhone +46 413 320 43 / +46 725 52 95 60 Email: larsg [at] vasterstad [dot] se (larsg[at]vasterstad[dot]se) Pu
https://www.particle-nuclear.lu.se/lars-gislen - 2026-05-29
Impact of differential and time-dependent autophagy activation on therapeutic efficacy in a model of Huntington disease Full Terms & Conditions of access and use can be found at https://www.tandfonline.com/action/journalInformation?journalCode=kaup20 Autophagy ISSN: (Print) (Online) Journal homepage: https://www.tandfonline.com/loi/kaup20 Impact of differential and time-dependent autophagy activat
https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/publication_in_autophagy.pdf - 2026-05-30
By utilising the effect of interfacial curvature on the freezing-point of liquids confined in capillaries, it is in principle possible to determine a pore-size distribution, from the curve of freezing-point against volume frozen. The method is formally similar to capillary condensation methods based on the Kelvin equation. Suitable experimental techniques are described. A comparison with the resul
Cet article explore une nouvelle théorie méta-éthique selon laquelle les jugements de valeur sont des expressions d’une sorte de croyance conditionnelle de celui qui émet ces jugements. Les jugements de valeur expriment la croyance que quelque chose est le cas à condition de que quelque chose d’autre soit le cas. L’objectif est ici de parvenir à une meilleure compréhension de ce point de vue. À ceThis paper explores a novel metaethical theory according to which value judgments express conditional beliefs held by those who make them. Each value judgment expresses the belief that something is the case on condition that something else is the case. The paper aims to reach a better understanding of this view and to highlight some of the challenges that lie ahead. The most pressing of these revo
120 credits The master’s programme in Molecular Genetics and Biotechnology focuses on the areas that constitute the basis in molecular genetics, including gene technology, cell biology, molecular biology and biotechnology. The programme is highly connected to research, with emphasis on genetic mechanisms underlying disease, mapping, and diagnostic methods. As a student, you will achieve practical
Background: Nigeria is a major contributor to the global malaria burden. The genetic diversity of malaria parasite populations as well as antibody responses of individuals in affected areas against antigens of the parasite can reveal the transmission intensity, a key information required to control the disease. This work was carried out to determine the allelic frequency of highly polymorphic Plas
Antimicrobial peptides (AMPs) are evolutionarily ancient molecules. They are essential innate immune response molecules that protect organisms from invading pathogens. Tissue factor pathway inhibitors (TFPI-1 and TFPI-2) C-terminal derived peptides exert host defense mechanisms against microbes. Studies showed that in human plasma, C-terminal TFPI-1 and -2 derived peptides mediate bacterial killin
Camille.Delepierre.THESIS SLOWING DOWN? WHY CITIES SHOULD DECREASE CAR SPEED AND WHY THEY DO NOT WITH LUND, MALMÖ AND LILLE EXAMPLES AUTHOR Camille Delepierre email: camille.delepierre@gmail.com Submitted in partial fulfilment of the requirements for the International Master’s Programme in Environmental Studies and Sustainability Science (LUMES) at Lund’s University, Sweden SUPERVISOR Dr. Lena Smi
https://www.lumes.lu.se/sites/lumes.lu.se/files/camille_delepierre.pdf - 2026-05-30
Micro-diamond in orogenic peridotite and other high grade metamorphics of the northern UHP domain, WGR, Norway: When and how did they form? Herman van Roermund1, Dirk Spengler2 & Hans Vrijmoed3 1 Structural Geology Group, Faculty of Earth Sciences, Utrecht University, Budapestlaan 4, 3508 TA, Utrecht, The Netherlands 2 Nansenstraße 24, 14471 Potsdam, Germany 3 Institut für Geologische Wissenschaf
https://www.geology.lu.se/sites/geology.lu.se/files/iec12-_excursion-guide-vol-3.pdf - 2026-05-30
Complement C2 deficiency (C2D) is associated with immunological diseases and increased susceptibility to invasive infections caused by encapsulated bacteria such as Neisseria menigitidis. In this study we evaluate the immunogenicity of vaccination against N. menigitidis in C2D. C2D patients (n=22) and controls (n=52) were given a tetravalent meningococcal polysaccharide vaccine. Serum bactericidal
In the wake of well-known instances of corporate misconduct – for example Enron in the U.S., and Skandia in Sweden – consumers ask for more transparent corporate brand practices to make corporate brands trustworthy. However, potentially, consumers who put their trust in brands may be sacrificing some of their own control, thus weakening themselves in the trusting relationship. The aim of this book
Transplantation of allogeneic embryonic neural tissue is a potential treatment for patients with Parkinson's and Huntington's diseases. The supply of human donor tissue is limited, and alternatives such as the use of animal (e.g., porcine) donor tissue are currently being evaluated. Before porcine grafts can be used clinically, strategies to prevent neural xenograft rejection must be developed. Kn
Hu11B6 is a monoclonal antibody that internalizes in cells expressing androgen receptor (AR)-regulated prostate-specific enzyme human kallikrein-related peptidase 2 (hK2; KLK2). In multiple rodent models, Actinium-225-labeled hu11B6-IgG1 ([225Ac]hu11B6-IgG1) has shown promising treatment efficacy. In the present study, we investigated options to enhance and optimize [225Ac]hu11B6 treatment. First,
It has previously been shown that sera from multiparous women have increased levels of anti-idiotypic antibodies specific for anti-HLA molecules. γ-Globulins prepared from these sera may be superior to commercial preparations of intravenous γ-globulin (IVIg) for inhibiting HLA alloimmunization. To test this, F(ab′)2 fragments prepared from either commercial IVIg or from the sera of men or multipar
Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix. Recently we reported that EDC34, a C-terminal peptide derived from TFPI-2, exerts a broad antimicrobial activity. In the present study, we describe a previously unknown antimicrobial mode of ac
Objective. Antileukoproteinase (ALP) is a physiologic inhibitor of granulocytic serine proteases. The present study was undertaken to investigate its therapeutic benefit in an antibody-transfer model of erosive polyarthritis and to elucidate its potential to interfere with immune complex-dependent inflammatory pathways. Methods. Arthritis development was induced in male (BALB/c x B10.Q)F-1 mice by
