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Introduction. Perioperative chemotherapy is the standard treatment for patients with locally advanced resectable gastric cancer. The prognostic relevance of MSI status in patients undergoing neoadjuvant chemotherapy remains unclear. Aim. To study the prognostic significance of MSI in gastric cancer patients undergoing perioperative CT. Materials and methods. The study included 173 patients with lo

TOI-836: A super-Earth and mini-Neptune transiting a nearby K-dwarf

We present the discovery of two exoplanets transiting TOI-836 (TIC 440887364) using data from TESS Sector 11 and Sector 38. TOI-836 is a bright (T = 8.5 mag), high proper motion (∼200 mas yr−1), low metallicity ([Fe/H]≈−0.28) K-dwarf with a mass of 0.68 ± 0.05 M and a radius of 0.67 ± 0.01 R. We obtain photometric follow-up observations with a variety of facilities, and we use these data sets to d

The Resection Rate of Synchronously Detected Liver and Lung Metastasis from Colorectal Cancer Is Low-A National Registry-Based Study

Population-based data on the incidence and surgical treatment of patients with colorectal cancer (CRC) and synchronous liver and lung metastases are lacking as are real-life data on the frequency of metastasectomy for both sites and outcomes in this setting. This is a nationwide population-based study of all patients having liver and lung metastases diagnosed within 6 months of CRC between 2008 an

Application of a Magnetic-field-induced Transition in Fe x to Solar and Stellar Coronal Magnetic Field Measurements

Magnetic fields play a key role in driving a broad range of dynamic phenomena in the atmospheres of the Sun and other stars. Routine and accurate measurements of the magnetic fields at all the atmospheric layers are of critical importance to understand these magnetic activities, but in the solar and stellar coronae such a measurement is still a challenge due to the weak field strength and the high

Wheat bran increases high-density-lipoprotein cholesterol in the rat

1. Five groups of male Sprague Dawley rats were given for 6 months a diet with high protein and fat contents but a very low dietary fibre content (group B), and this diet mixed with (g/kg) 50 low-methoxyl pectin (group L), 50 high-methoxyl pectin (group H), 50 guar gum (group G) and 200 wheat bran (group WB, corresponding to 100 wheat fibre) respectively. 2. The weight increment was significantly

Forces applied at the footrest during ergometer kayaking among female athletes at different competing levels – A pilot study

BackgroundPower output and force development during exercise are thought to be important indices of performance in elite athletes. The aim of this preliminary study was to determine the forces applied at the footrest during ergometric kayaking in individual kayakers at different competitive levels.MethodsThree elite female kayakers participated voluntarily in the study. Oxygen consumption (VO2) an

Caught between principles and politics : Challenges and opportunities for capacity development from governmental donors’ perspectives

Capacity development —an integral part of development cooperation in general and for disaster risk reduction (DRR) in particular—has had limited success so far. This article investigates capacity development challenges and opportunities from the viewpoint of the staff of progressive governmental donor agencies. Data were obtained from 26 semi-structured interviews with informants from seven donor

Treatment of synthetic textile wastewater containing dye mixtures with microcosms

The aim was to assess the ability of microcosms (laboratory-scale shallow ponds) as a post polishing stage for the remediation of artificial textile wastewater comprising two commercial dyes (basic red 46 (BR46) and reactive blue 198 (RB198)) as a mixture. The objectives were to evaluate the impact of Lemna minor L. (common duckweed) on the water quality outflows; the elimination of dye mixtures,

Pesticide exposure as risk factor for non-Hodgkin lymphoma including histopathological subgroup analysis.

We report a population based case-control study of exposure to pesticides as risk factor for non-Hodgkin lymphoma (NHL). Male and female subjects aged 18-74 years living in Sweden were included during December 1, 1999, to April 30, 2002. Controls were selected from the national population registry. Exposure to different agents was assessed by questionnaire. In total 910 (91 %) cases and 1016 (92%)

Effect of food intake on left and right ventricular systolic tissue Doppler measurements.

Systolic tissue Doppler measurements (s') have been used to measure the velocity in myocardial motion and are a valuable tool for evaluating the systolic function of the left and right ventricles. Digestion of food is known to significantly alter hemodynamics and may therefore affect s'. The effect of food intake on s' parameters has not yet been studied. We assessed whether s' is affected by food

Vacuum-assisted closure therapy for deep sternal wound infections: the impact of learning curve on survival and predictors for late mortality.

The aim of this study was to evaluate the possible learning curve effects on survival during the introduction of vacuum-assisted closure (VAC) therapy in patients with deep sternal wound infection (DSWI). Furthermore, predictors of late mortality were analysed and causes of late death were examined. Fifty-three patients (early Group, n = 26, January 1999 to July 2001 versus late group, n = 27, Aug

Percutaneous cholecystostomy: a bridge to surgery or definite management of acute cholecystitis in high-risk patients?

OBJECTIVE: Cholecystectomy is the standard treatment for acute cholecystitis, but in high-risk patients with serious comorbidity and in patients of advanced age there is substantial morbidity and mortality associated with the intervention. In these selected patients, percutaneous cholecystostomy (PCS) is an alternative mode of management. The aim of the present study was to evaluate the outcome of

Knee laxity after complete anterior cruciate ligament tear: a prospective study over 15 years.

There is limited knowledge of knee laxity in the long term after a complete anterior cruciate ligament (ACL) tear treated without ACL reconstruction. The aim of this study was (1) to describe the clinical course of knee laxity after a complete ACL tear over 15 years, and (2) to study the association between knee laxity and meniscal injuries and the development of knee osteoarthritis (OA). We studi

Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels.

Identifying the genetic variants that regulate fasting glucose concentrations may further our understanding of the pathogenesis of diabetes. We therefore investigated the association of fasting glucose levels with SNPs in 2 genome-wide scans including a total of 5,088 nondiabetic individuals from Finland and Sardinia. We found a significant association between the SNP rs563694 and fasting glucose

The Gorkha Aftershocks - A Window of Opportunity to Human Development in Okharpauwa, Nepal?

The Gorkha earthquake that happened on the 25th of April and its aftershocks on the 26th 2015 was a remarkable event in Nepal’s history. Okharpauwa, a village development committee in Nuwakot District, was considerably affected by the aftershocks and the affected people were in the process of recovering when this master’s thesis was written. A dominant idea within disaster recovery literature is

Ventilation analysis for control room in submarine A26

This thesis represents results from a numerical study of the ventilation system in the control room in the Swedish submarine A26. This thesis's primary focus is to study and examine the performance and efficiency of the current ventilation system. The ventilation system is very critical and crucial in enclosed environments. Many factors and parameters are affected by the installed system. In c

Dependency of dinoflagellate vertical migration on salinity stratification

Increasing precipitation and surface water temperature due to global change may strengthen the salinity gradient in coastal regions, which could influence the behaviour of dinoflagellate migration. We studied diel vertical migration (DVM) behaviour in the dinoflagellates Prorocentrum minimum and Heterocapsa triquetra using vertically stratified laboratory columns with 3 different salinity gradient

Potentiella störningsmoment i form av muntlig kommunikation på en intensivvårdsavdelning

Bakgrund: Studier visar på att ljudnivån på en intensivvårdsavdelning är hög. I många studier har man kommit fram till att en stor del av ljudet orsakas av samtal mellan personal. Samtal svarar för 26% av allt ljud på en intensivvårdsavdelning. Sömn är en grundläggande komponent för att återställa energi och fysisk hälsa efter sjukdom. Upp till 58 % av alla patienter som sover vaknar på grund av o

The Impact of Military Orders on the Palestinians’ Right to Water Access : a content analysis of IDF’s Military Orders regarding water in light of IHL and ICCPR Article 26

The aim of this thesis is to explore what impacts the IDF’s Military Orders regarding water have on Palestinians in the West Bank, taking international humanitarian law (IHL) and International Convention on Civil and Political Rights (ICCPR) into consideration. Thus, to discover whether or not Israel’s actions are compatible with IHL and treats everyone equal before the law, as stated in ICCPR Art