Filtyp
Background: This study aimed to evaluate whether an increasing grade of obesity is associated with inferior outcomes after lumbar disc herniation (LDH) surgery. Methods: We retrieved data from the Swedish register for spine surgery regarding patients aged 20–64 who underwent LDH surgery from 2006–2016 and had preoperative and one-year postoperative data. A total of 4156 patients were normal weight
Objective: To identify prognostic factors for patients with advanced persistent, recurrent, or 2nd primary oral cavity squamous cell carcinoma (OCSCC) potentially unsuitable for salvage surgery with free tissue flap (FTF) reconstruction. Materials and methods: A population-based cohort of 83 consecutive patients with advanced OCSCC who underwent salvage surgery with FTF reconstruction at a tertiar
Purpose: To investigate incidence and location of locoregional recurrence (LRR) in patients who have received postoperative locoregional radiation therapy (LRRT) for primary breast cancer. LRR-position in relation to applied radiotherapy and the primary tumor biological subtype were analyzed with the aim of evaluating current target guidelines and radiation therapy techniques in relation to tumor
Background: To determine characteristics that might affect survival times in Alzheimer’s disease (AD) patients treated with cholinesterase inhibitors (ChEI) in clinical practice, and create statistical models of estimated life-span after AD diagnosis. Method: The Swedish Alzheimer Treatment Study (SATS) is a prospective, observational, multicenter study to evaluate the use of long-term ChEI therap
Aims/hypothesis: Type 1 and type 2 diabetes differ with respect to pathophysiological factors such as beta cell function, insulin resistance and phenotypic appearance, but there may be overlap between the two forms of diabetes. However, there are relatively few prospective studies that have characterised the relationship between autoimmunity and incident diabetes. We investigated associations of a
Objective: To investigate whether midlife atherosclerosis is associated with different dementia subtypes and related underlying pathologies. Methods: Participants comprised the cardiovascular cohort of the Swedish prospective population-based Malmö Diet and Cancer Study (N = 6,103). Carotid plaques and intima media thickness (IMT) were measured at baseline (1991–1994). Dementia incidence until 201
Background Fidanacogene elaparvovec, an adeno-associated virus (AAV) gene-therapy vector for hemophilia B containing a high-activity human factor IX variant (FIX-R338L/FIX-Padua), was associated with sustained factor IX activity in a phase 1-2a study. Methods We conducted a phase 3 open-label study of fidanacogene elaparvovec at a dose of 5×1011 vector genome copies per kilogram of body weight. Me
BACKGROUND: Heart failure (HF) is a common chronic condition that affects over 26 million people worldwide. It is a progressive and debilitating disease with a broad symptom profile, intermittently marked by periods of acute decompensation. People with HF generally do not self-manage their condition well (eg, monitoring symptoms, taking medications regularly, physical activity, etc). A better unde
Motivation: Pollinators play a crucial role in maintaining Earth's terrestrial biodiversity. However, rapid human-induced environmental changes are compromising the long-term persistence of plant-pollinator interactions. Unfortunately, we lack robust, generalisable data capturing how plant-pollinator communities are structured across space and time. Here, we present the EuPPollNet (European Plant-
Independent estimation and verification of fossil CO2 emissions on a regional and national scale are crucial for evaluating the fossil CO2 emissions and reductions reported by countries as part of their nationally determined contributions (NDCs). Top-down methods, such as the assimilation of in situ and satellite observations of different tracers (e.g., CO2, CO, Δ14CO2, XCO2), have been increasing
Objectives Accumulating evidence suggested that the laminin Î 32 (LAMC2) expression level was upregulated in various cancers. However, the potential prognostic value of LAMC2 in cancers remains unclear. We conducted a meta-analysis to clarify the association of LAMC2 expression with prognosis. Design We searched Embase, Web of Science and PubMed (up to 25 November 2021) to collect all eligible stu
OBJECTIVE: To explore associations of HLA class II genes (HLAII) with the progression of islet autoimmunity from asymptomatic to symptomatic type 1 diabetes (T1D).RESEARCH DESIGN AND METHODS: Next-generation targeted sequencing was used to genotype eight HLAII genes (DQA1, DQB1, DRB1, DRB3, DRB4, DRB5, DPA1, DPB1) in 1,216 participants from the Diabetes Prevention Trial-1 and Randomized Diabetes P
BACKGROUND: Although most pediatric radial neck fractures can be treated with either immobilization alone or closed reduction and immobilization, a small subset result in permanent loss of motion despite surgical management. We sought to characterize the most problematic fractures and correlate final outcomes with both presenting fracture characteristics and the reduction achieved through surgical
Background: In addition to the established association between general obesity and breast cancer risk, central obesity and circulating fasting insulin and glucose have been linked to the development of this common malignancy. Findings from previous studies, however, have been inconsistent, and the nature of the associations is unclear.Methods: We conducted Mendelian randomization analyses to evalu
Purpose: This study aimed to assess the accuracy of patient-specific absorbed dose calculations for tumours and organs at risk in radiopharmaceutical therapy planning, utilizing hybrid planar-SPECT/CT imaging. Methods: Three Monte Carlo (MC) simulated digital patient phantoms were created, with time-activity data for mIBG labelled to I-123 (LEHR and ME collimators) and I-131 (HE collimator). The s
Shale gas extraction commonly known as fracking had support from the UK government with their ‘all out for shale’ policy. Despite this industry has struggled to establish itself mainly due to strong opposition from communities concerned about environmental and health impacts. Most research into the impacts of fracking is concerned with either environmental degradation or physical health impacts wh
Research strategy 2026-06-03 1 RESEARCH STRATEGY 2026-06-03 STYR 2026/1296 Department of Informatics Research strategy for the Department of Informatics, Lund University School of Economics and Management Decided by the Board of the Department of Informatics on June 3, 2026. The strategy is valid three years from the date of the decision. The research at the Department of Informatics focuses on th
https://www.lusem.lu.se/internal/sites/lusem.lu.se.internal/files/2026-06/Research%20strategy%202026-06-03.pdf - 2026-07-16
Antologi SIRen revidering 191120.pdf Hållbar renovering ur ett helhetsperspektiv En antologi från forskningsmiljön SIRen Redaktörer: Stefan Olander, Kristina Mjörnell, Paula Femenías, Elisabeth Helsing, Petter Wallentén H ållbar renovering ur ett helhetsperspektiv - En antologi från forskningsm iljön SIR en Formas finansierar en stark transdisciplinär forskningsmiljö för helhetssyn på hållbar reno
Inbjudan I n s t i t u t i o n e n f ö r m i l j ö v e t e n s k a p l i g u t b i l d n i n g PRELIMINÄRT SCHEMA PRELIMINÄRT Schema för MVET10 miljöskydd, 15 hp ht 15 Kurstid: 31 augusti – 1 november 2015 Kursansvarig: Högni Hansson 0721-55 56 48, hogni.hansson@cec.lu.se Introduktion: måndagen den 31 augusti 2015, Ekologihuset, Maskrosen, kl. 10.15-11.00. Lärare: Högni Hansson hogni.hansson@cec.l
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/schema_mvet10_ht15_v3.pdf - 2026-07-16
Case assignment and the linear order of coordinated verbs* Jim Wood Yale University Einar Freyr Sigurðsson The Árni Magnússon Institute for Icelandic Studies Oddur Snorrason Queen Mary University of London Abstract In this paper, we draw on corpus data to show that in Icelandic, verbs that assign distinct cases can be coordinated and share a single object: the verb on the right determines the case
