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Before performing 177Lu-DOTATATE therapy for neuroendocrine tumors, somatostatin receptor (SSTR) PET imaging is currently used to confirm sufficient tumor SSTR expression, but it also has potential to be used to personalize treatment by predicting absorbed doses to critical organs. This study aims to validate the predictive capability of SSTR PET in anticipating renal absorbed dose in the first cy
Evidence from neuropathological cohorts indicates that a CSF α-synuclein (α-syn) seed amplification assay (SAA) might provide quantitative kinetic parameters correlating with α-syn pathology burden in patients with Lewy body disease (LBD). Studies are needed to assess their longitudinal trend during the presymptomatic and clinical disease phases and their correlation with measures of disease progr
IMPORTANCE: The number of patients prescribed long-term opioids and benzodiazepines and complications from their long-term use have increased. Information regarding the perioperative outcomes of patients prescribed these medications before surgery is limited.OBJECTIVE: To determine whether patients prescribed opioids and/or benzodiazepines within 6 months preoperatively would have greater short- a
Popular Abstract in Swedish Kol-kolinteraktioner utgör starka kemiska bindningar. Detta innebär att de är relativt svåra att både bryta och bilda. Föreliggande avhandling sammanfattar mekanistiska studier av två reaktioner, Stillereaktionen och Heckreaktionen, med hjälp av vilka kol-kolbindningar kan bildas. Ett vanligt förekommande sammanfattningsnamn för denna typ av reaktioner är korskopplingsrThe present thesis deals with various types of palladium(II) and platinum(II) complexes and their use in homogeneous catalysis. The focus has been devoted to mechanistic investigations concerning the Stille and Heck reactions and studies under both catalytic and stoichiometric conditions were conducted. As a stoichiometric probe for studying the transmetallation step in the Stille reaction the pl
Popular Abstract in Swedish Kostfiber visar på gynnsamma effekter på blodsockersvar, inflammationsmarkörer och blodfetter utifrån tre humanstudier som genomfördes i detta arbete. I en av studierna analyserades blod och urin med metabolomik. Det är en metod där man analyserar alla små molekyler (metaboliter) som finns i provet med hjälp av vätskekromatografi kopplat till masspektrometri. Med hjälp It is well-known that dietary fibre can have a positive effect on the development of lifestyle-dependent diseases such as cardiovascular disease and type 2 diabetes. However, the effect may be different for different kinds of fibre and different sub-populations at risk. Therefore, the effects of three different kinds of fibre on postprandial and long-term response in healthy subjects were investig
Background: Current systemic therapies for metastatic pancreatic ductal adenocarcinoma are associated with poor outcomes with a 5-year overall survival rate under 5%. We aimed to assess the safety and antitumour activity of mitazalimab, a human CD40 agonistic IgG1 antibody, with modified FOLFIRINOX (mFOLFIRINOX; fluorouracil, leucovorin, oxaliplatin, and irinotecan), in chemotherapy-naive patients
Importance: Comprehensive and timely monitoring of disease burden in all age groups, including children and adolescents, is essential for improving population health.Objective: To quantify and describe levels and trends of mortality and nonfatal health outcomes among children and adolescents from 1990 to 2015 to provide a framework for policy discussion.Evidence Review: Cause-specific mortality an
Background: Survivors of childhood cancer are at increased risk for a wide range of late effects. However, no large population-based studies have included the whole range of somatic diagnoses including subgroup diagnoses and all main types of childhood cancers. Therefore, we aimed to provide the most detailed overview of the long-term risk of hospitalisation in survivors of childhood cancer. Metho
Glycosaminoglycans (GAGs) are polysaccharides produced by essentially all mammalian cells. Due to their enormous structural diversity, they are involved in many biological processes both in health and disease, including all stages of tumor progression. GAGs are normally attached to a core protein as a part of a proteoglycan; however, GAG biosynthesis can be induced by compounds composed of a xylos
Chronic pain including temporomandibular disorder (TMD) pain involves a complex interplay between peripheral and central sensitization, endogenous modulatory pathways, cortical processing and integration and numerous psychological, behavioral and social factors. The aim of this study was to compare spectroscopic patterns of N-Acetyl-aspartate (NAA), total creatine (tCr), choline (Cho), myo-inosito
Background: The emergence of highly active novel agents has led some to question the role of autologous haematopoietic stem-cell transplantation (HSCT) and subsequent consolidation therapy in newly diagnosed multiple myeloma. We therefore compared autologous HSCT with bortezomib–melphalan–prednisone (VMP) as intensification therapy, and bortezomib–lenalidomide–dexamethasone (VRD) consolidation the
Importance: Soft drinks are frequently consumed, but whether this consumption is associated with mortality risk is unknown and has been understudied in European populations to date.Objective: To examine the association between total, sugar-sweetened, and artificially sweetened soft drink consumption and subsequent total and cause-specific mortality.Design, Setting, and Participants: This populatio
Purpose: Recent developments in external radiotherapy and its utilization with artificial in- telligence (AI) enables advanced treatment plans for a range of different disease sites. By adapting to the anatomy of the day, target coverage can be ensured while sparing more healthy tissue. The purpose of this project was to study the feasibility and benefits of daily cone beam computed tomography (CB
Neurodegenerative diseases have traditionally been defined in vivo based on clinical symptoms. However, the development of biomarkers has enabled a shift towards in vivo biological definitions. There is now a need to characterize memory clinic populations using multi-dimensional biomarker information. Here, we employed a data-driven approach to develop a biological framework for categorizing indiv
Välkomna till Språk- och litteraturcentrum! Välkomna till Språk- och litteraturcentrum och till ämnet franska! www.sol.lu.se/franska Bienvenu(e)s au Centre de langues et de littérature et aux études de français ! Introduktionsmöte Franska, grundkurs (1-30 hp) FRAA21 (hel- och halvfart) 2026-01-19 Thierry Gilles, universitetsadjunkt i franska Malin Ågren, lektor i fransk språkvetenskap och studiere
https://www.sol.lu.se/media/utbildning/dokument/kurser/FRAA21/20261/Introduction_FRAA21_VT2026_del_1.pdf - 2026-07-04
Work environment representative | Saco-S council at Umeå University Hoppa till huvudinnehåll About us Contact Workplace representative Arts and Humanities Medicine Social Sciences Science and Technology Others Work environment representative Calendar Saco-S Umeå universitet Swedish About us Contact Workplace representative Work environment representative Calendar Start > Trustee > Local union work
Guidance and support for managing outbound exchange students Announcement of Faculty agreements and university-wide agreementsExchange places at partner universities are announced at each faculty, whether they are subject-specific or university-wide places. The faculties are responsible for their own process of announcing their faculty- and subject specific exchange places, while the Division of G
Master Thesis LUMES 1999-2000 Lond University Correlation of The Planning Process with Environmental Responsive and Healthy Buildings Case studies in Sweden and Malaysia. Author: YokeChin Lai, M. Eng. (Mechanical), Institute ofNoise & Vibration, Universiti Teknologi Malaysia, Kuala Lumpur, Malaysia. e-mail: yokechin lai@hotmai1.com Supervisor: Kerstin Gustafsson, Environmental Manager, Division of
https://www.lumes.lu.se/sites/lumes.lu.se/files/lai_yokechin.pdf - 2026-07-16
SECTION I: INTRODUCTION LUMES – LUND UNIVERSITY INTERNATIONAL MASTER’S PROGRAMME IN ENVIRONMENTAL SCIENCE AN ANALYSIS ON THE MANAGEMENT OF SCARCE WATER RESOURCES IN JORDAN - A SYSTEM’S APPROACH MASTER’S THESIS BY ROBA EL-GHADBAN E-mail: roba.ghadban@telia.com _____________________________________________________________________ SUPERVISOR Prof. Lars Bengtsson Department of Water Resources Engineer
https://www.lumes.lu.se/sites/lumes.lu.se/files/roba_elghadban.pdf - 2026-07-16
Behandling av personuppgifter för forskningsändamål 1 Regeringens proposition 2017/18:298 Behandling av personuppgifter för forskningsändamål Prop. 2017/18:298 Regeringen överlämnar denna proposition till riksdagen. Stockholm den 6 september 2018 Stefan Löfven Helene Hellmark Knutsson (Utbildningsdepartementet) Propositionens huvudsakliga innehåll I propositionen föreslås vissa ändringar i svensk
https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/prop2017_18_298.pdf - 2026-07-16
