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The glycaemic index (GI) concept was originally introduced to classify different sources of carbohydrate (CHO)-rich foods, usually having an energy content of > 80 % from CHO, to their effect on post-meal glycaemia. It was assumed to apply to foods that primarily deliver available CHO, causing hyperglycaemia. Low-GI foods were classified as being digested and absorbed slowly and high-GI foods as b
Background: Laser photocoagulation is a well-established treatment for diabetic retinopathy but the mechanism behind its effectiveness has not been elucidated. The protein kinase C (PKC) family is a group of enzymes which has been the subject of extensive interest in clinically related research since the advent of its role in the pathogenesis of diabetic retinopathy. With this study we wanted to e
Profound hypoglycemia causing the disappearance of spontaneous EEG activity was induced by insulin in rats. For analysis of cerebral cortical concentrations of labile phosphates, glycolytic metabolites and amino acids, the brain was frozen in situ. For microscopic analysis of the corresponding cerebral cortical areas the brain was fixed by perfusion. Hypoglycemia with an isoelectric EEG for 30 and
Popular Abstract in Swedish I Sverige har intranät inom loppet av ett par år införts i drygt hälften av alla organisationer – privata och offentliga. Intranät har av många setts som ett verktyg för att effektivisera kommunikationen och lärandet. Behovet av effektiv kommunikation och lärande har accelererat under 1990-talet med en allt större konkurrens mellan organisationerna. En god tillgång till
Objective. Infliximab, an anti-tumor necrosis factor alpha (anti-TNF alpha) antibody, is effective in the treatment of several immunoinflammatory diseases. However, many patients experience primary or secondary response failure, suggesting that individualization of treatment regimens may be beneficial. This study was undertaken to investigate whether serologic monitoring of infliximab bioavailabil
Considering the current resources scarcity, Wastewater Treatment Plants (WWTP) should be adapted to become more sustainable. For example, it is possible to recover resources present in municipal wastewater. However, regional studies about integration of resource recovery processes at different scales or about the main barriers to implementation in developing countries are missing in the literature
Background: Bladder cancer is categorized as non-muscle invasive (NMIBC) or muscle invasive (MIBC). NIMBC makes up around 70% of the cases and although it is less aggressive, the recurrence rate is 50-70%, thus requiring extensive monitoring. Additionally, there is a risk of progression into MIBC with a 5-year survival of only 50% even when treated with radical cystectomy. Immune checkpoint inhibi
In this study an algorithm was developed for calculating maximum detectable distance (MDD) for mobile gamma-ray detection of lost sources in-situ for some common mobile spectrometer systems and gamma sources (137Cs and 60Co). The MDD is a function of detector efficiency, vehicle speed, acquisition time interval, radiation background level and accepted frequency of false alarms. To test its accurac
Discontinuous Galerkin (DG) methods offer a great potential for simulations of turbulent and wall bounded flows with complex geometries since these high-order schemes offer a great potential in handling eddies. Recently, space-time DG methods have become more popular. These discretizations result in implicit schemes of high order in both spatial and temporal directions. In particular, we consider
Zeolites are widely used in catalysis, gas separation, ion exchange, etc. due to their superior physicochemical properties, which are closely related to specific features of their framework structures. Although more than two hundred different framework types have been recognized, it is of great interest to explore from a crystallographic perspective, the atomic positions, surface terminations, por
Plant species beta diversity is influenced by spatial heterogeneity in the environment. This heterogeneity can potentially be characterised with the help of remote sensing. We used WorldView-2 satellite data acquired over semi-natural grasslands on The Baltic island of Öland (Sweden) to examine whether dissimilarities in remote sensing response were related to fine-scale, between-plot dissimilarit
Aims Oral anticoagulation with vitamin K antagonists (VKAs) for stroke prevention in atrial fibrillation (AF) is effective but has significant limitations. AZD0837, a new oral anticoagulant, is a prodrug converted to a selective and reversible direct thrombin inhibitor (AR-H067637). We report from a Phase II randomized, dose-guiding study (NCT00684307) to assess safety, tolerability, pharmacokinet
Bakgrund: Personer med psykisk ohälsa har ofta en nedsatt förmåga att bearbeta sinnesintryck. Tidigare har kopplingen mellan det individuella sättet att hantera sinnesintryck och olika sociodemografiska faktorer undersökts hos psykiskt friska personer, men studier gällande detta saknas för personer med psykisk ohälsa. Syfte: Att undersöka sensoriska bearbetningsmönster och deras eventuella kopplBackground: People with mental illness often have a reduced ability to process sensory inputs. Previously, the link between the individual way of dealing with sensory inputs and sociodemographic factors has been investigated in mentally healthy people, but there’s a lack of similar studies for people with mental illness. Aim: To investigate sensory processing patterns and their possible connecti
Kandidatarbetets syfte har varit att ta fram ett hjälpmedel för studenter på sedimentologikursen vid Geologiska institutionen på Lunds universitet. Hjälpmedlet är tänkt att kunna användas utan lärares hjälp då ett ökat studentantal och försämrad ekonomi på institutionen begränsar lärarnas möjlighet att kunna ge alla studenter den hjälp de behöver för att nå kursmålen. Enkätundersökningar och kursvThe purpose of this Bachelor thesis has been to create an aid for the students at the Department of Geology at Lund’s University. The resource is supposed to be usable without assistance from a teacher. This since the number of students has increased markedly over the last few years while the economic means of the department have decreased. This has reduced the teachers abilities to give all the s
När blodet är slut... När man normalt bestämmer blodgrupper använder man sig av ett antiserum mot den blodgruppen man är intresserad av. Det finns över 30 st blodgruppsystem varav de vanligaste folk känner till är ABO och Rh (Rhesus), det vill säga om man är A, B, O, eller AB och om man är positiv eller negativ i RhD. När man blir gravid eller får en blodtransfusion utsätts man för blod som inte
The raising of fur animals is generally a polluting activity, today and historically. This study is focused on the breeding of minks. I concluded that this is an industry that has significantly polluting places it have been active on. The main and most interesting source of contamination is the use of pesticides, which always has been frequently used. The pesticides used often entail very high ris
BACKGROUND: The risk of infection-related death is high in patients undergoing dialysis. This study aimed to identify the modifiable risk factors for PD-related infections in patients undergoing peritoneal dialysis.METHODS: This was a population-based retrospective cohort study conducted in Skåne, South Sweden, which included all patients receiving peritoneal dialysis (PD) between 2011 and 2020. T
Long time series of satellite remotely sensed Normalized Difference Vegetation Index (NDVI) as an indicator of vegetation greenness can be used in a broad range of research topics such as climate change, vegetation dynamics and desertification monitoring. The first phase of this study tests a practical method using Hyperion imagery onboard on Earth Observing-1 (EO1) spacecraft for simulation of MO
