Filtyp
In this paper, a mathematical model is presented by which the cutting forces in gear form milling process are predicted using the mechanistic approach. To use this approach, a detailed description of the chip geometry is needed. Eccentricity and run-out tool errors are considered, which is of great importance as the chip thickness will by these errors vary for the subsequent cuts. The chip geometr
In this editorial, the author states that the importance of casting off blinders applies to topics and disciplines as much as to individuals. There is no disagreement in psychology that we are mostly ignorant of the various neurophysiological and cognitive substrates and limitations of our conscious experience, but there are other background processes that determine what, how, and even whether we
A wide divergence has been detected in the telomeric sequences among budding yeast species. Despite their length and homogeneity differences, all these yeast telomeric sequences show a conserved core which closely matches the consensus RAP1-binding sequence. We demonstrate that the RAP1 protein binds this sequence core, without involving the diverged sequences outside the core. in Saccharomyces ca
This Report summarizes the results of the activities of the LHC Higgs Cross Section Working Group in the period 2014-2016. The main goal of the working group was to present the state-of-the-art of Higgs physics at the LHC, integrating all new results that have appeared in the last few years. The first part compiles the most up-to-date predictions of Higgs boson production cross sections and decay
Cardiac fibroblasts (CFs) play a key role in response to injury and remodeling of the heart. Nucleotide (P2) receptors regulate the heart but limited information is available regarding such receptors in CFs. We thus sought to determine if extracellular nucleotides regulate fibrotic responses (e.g., proliferation, migration and expression of profibrotic markers) of CFs in primary culture. UTP incre
Due to the great variation in approaches to psychiatric rehabilitation, the literature does not provide a uniform description of these methods. In this review, outcomes in terms of subjective quality of life are discussed in relation to vocational training, activity-based rehabilitation, case management, and social skills training. Relationships between aspects of daily life and subjective quality
ActiGraph acceleration data are processed through several steps (including bandpass filtering to attenuate unwanted signal frequencies) to generate the activity counts commonly used in physical activity research. We performed three experiments to investigate the effect of sampling frequency on the generation of activity counts. Ideal acceleration signals were produced in the MATLAB software. There
Human disturbance can be a severe problem for some animal species. Behavioural ecology theory predicts that sensitivity to mortality risks, and thereby to disturbance, will be related to life-history characteristics. Long-lived species with low reproductive rates are expected to have a high cost of predation and therefore avoid risks strongly. In this paper we quantify the effect of roads on the A
Background: Cyclic opening and closing of lung units during tidal breathing may be an important cause of iatrogenic lung injury. We hypothesized that airway closure is uncommon in children with healthy lungs when inspiratory pressures are kept low, but paradoxically may occur when inspiratory pressures are increased. Methods: Elastic equilibrium volume (EEV) and closing capacity (CC) were measured
The sequence diversity of the entire mitochondrial control region (CR) of three meadow viper (Vipera ursinii) populations was analysed and compared to previously documented nuclear genetic variability at the major histocompatibility complex (MHC) Class I loci. One of the populations, a small and inbred Hungarian population, exhibited no MHC polymorphism, whereas the two other, sampled from large v
Background: Moderately displaced two-fragment fractures of the radial head have been treated predominantly nonoperatively. Recently, however, open reduction and internal fixation has gradually gained interest, without clear evidence that initial nonoperative treatment leads to an unfavorable outcome. As a consequence, the purpose of the present study was to evaluate the long-term outcome after the
Fluorescence lidar is a non-invasive, remote sensing technique that makes it possible to extend the application of the laser-induced fluorescence technique to the outdoor environment where uncontrolled, external conditions must be met. Although initially developed for the investigation of marine environment and vegetation, in the past decade this technique has been successfully applied to the fiel
The purpose of this study is to identify and structure challenges of measuring performance of the Sales and Operations Planning (S&OP) process. A multiple case study methodology was applied. Qualitative data was collected via 22 structured interviews with managers from six case companies in various industries. A process oriented framework was proposed by structuring the challenges based on two
A fully integrated remote antenna unit (RAU) intended for fiber-fed distributed multiple-input multiple-output systems is presented. The circuit is designed for narrowband (60 MHz) time-division duplex systems, where an IF over fiber approach is chosen to facilitate the use of low-cost optical components and integrated photodetectors. A novel antenna switch control scheme is introduced, which enab
Background Transcatheter aortic valve replacement (TAVR) has become an established therapeutic option for patients with symptomatic, severe aortic valve stenosis (AS) who are ineligible or at high risk for conventional valvular surgery. In Northwestern Europe, the TAVR technology is also increasingly used to treat patients with an intermediate risk profile. Methods and results The study was design
Synchrotron radiation X-ray tomographic microscopy (SRXTM) was used to virtually dissect and peel the shields off of the microscopic, bivalved phosphatocopine crustaceans in the Cambrian ‘Orsten’ type of preservation of Sweden. Doing so opened up for an array of concealed internal structures to be observed in a fully enclosed specimen of Hesslandona ventrospinata and a semi-enclosed specimen of He
Continual environmental degradation and an unfair distribution of environmental burdens and benefits are two great challenges for humanity. Economic growth is often taken for granted when planning for the future. However, it is often argued that maintaining economic growth conflicts with keeping human activities adjusted to ecological boundaries and finite resources, at least for the more-develope
Automated soil moisture systems are commonly used in precision agriculture. Using low-cost sensors, the spatial extension can be maximized, but the accuracy might be reduced. In this paper, we address the trade-off between cost and accuracy comparing low-cost and commercial soil moisture sensors. The analysis is based on the capacitive sensor SKU:SEN0193 tested under lab and field conditions. In a
Purpose: The research community has focused on defining reliable biomarkers for the early detection of the pathological hallmarks of Alzheimer’s disease (AD). In 2017, the Geneva AD Biomarker Roadmap initiative adapted the framework for the systematic validation of oncological biomarkers to AD, with the aim to accelerate their development and implementation in clinical practice. The aim of this wo
We propose drl-RPN, a deep reinforcement learning-based visual recognition model consisting of a sequential region proposal network (RPN) and an object detector. In contrast to typical RPNs, where candidate object regions (RoIs) are selected greedily via class-agnostic NMS, drl-RPN optimizes an objective closer to the final detection task. This is achieved by replacing the greedy RoI selection pro
