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Detection of genotype-specific human papillomavirus (HPV) capsid antibody in serum suggests past HPV infection. Also, these antibodies appear to correlate with vaccine-induced protection against infection, at least in animal models. However, each laboratory defines a reactive result differently and there is no agreed definition of what level of response indicates sero-reactivity. Standardization o

Written submissions or comments as a response on an EIS (Environmental Impact Statement) rank as one of the most common forms of public participation. Within public participation research there appears to be an international dearth of knowledge concerning such written submissions. The possible impact of such responses on an EIS is - with few exceptions - seldom put in focus. The aim in the present

About 10% of the patients with neurofibromatosis type 1 (NF1) develop malignant peripheral nerve sheath tumors (MPNSTs), accounting for half of all MPNST cases. Several nonrandom chromosomal aberrations have been found, but the target genes remain mostly unrecognized. Mutations in the NF1 and TP53 genes have been found in some MPNSTs, and recent data from mouse models support a synergistic effect

In this paper we study an optimization problem relevant for wireless networks. In such networks links are subject to capacity disruptions caused by changing weather/channel condition that force to adapt the modulation and coding schemes to the observed condition. To cope with this issue in network optimization, we need to consider a so called link availability set A and a routing strategy that can

Popular Abstract in Swedish Brist på fria radikaler kan ge artrit Fagocytiska celler i vårt immunförsvar producerar fria syre-radikaler för att eliminera fagocyterade (uppätna) mikroorganismer. Produktionen av dessa syre-radikaler sker med hjälp av ett enzymkomplex (NADPH oxidas) i cellmembranet samt i membranet på de fagosomer, innehållande mikroorganismer, som bildas i och med fagocytos. MännisThe aim of this thesis is to defend a novel mechanism that triggers arthritis susceptibility in both rats and mice through reduced production of reactive oxygen species (ROS), but also to introduce a novel model for chronic relapsing arthritis. Five papers are included, all of which employ animal models for rheumatoid arthritis and one that also uses animal models for multiple sclerosis. Paper I a

Popular Abstract in Swedish Artiodactyla (partåiga hovdjur) är uppdelad i tre underordningar, Suiformes (grisar och flodhästar), Tylopoda (kameler och lamor) och Ruminantia (kor, hjortar, antiloper och giraffer). Studien syftade till att analysera släktskapen mellan de olika underordningarna och ordningen Cetacea (valar) genom att sekvensera mitokondrie DNA och jämföra sekvenserna. I våra släktskArtiodactyla (eved-toed ungulates) and Cetacea (whales) are two mammalian orders that are commonly recognised as sistergroups. Recently it has been suggested that Cetacea originated within Artiodactyla, but the relationships among the different artiodactyl lineages and Cetacea have not been conclusively established. In the present study the mitochondrial genome of the pig (Sus scrofa), the hippopo

It is currently unclear how often genes that are mutated to cause rare, early-onset monogenic forms of disease also harbor common variants that contribute to the more typical polygenic form of each disease. The gene for MODY3 diabetes, HNF1 alpha, lies in a region that has shown linkage to late-onset type 2 diabetes (12q24, NIDDM2), and previous association studies have suggested a weak trend towa

Slow-release strong opioids (SRSO) are indicated in patients with severe chronic pain. Side effects, lack of efficacy and risk of dependency limit their use in clinical practice. The aim of this study was to explore prescription patterns of SRSO in Swedish real-world data on patients with a diagnosis related to chronic pain (DRCP). Patient-level data were extracted from the national prescriptions

Slipped-strand mispairing at sites containing so-called coding repeats (CRs) can lead to phase variation of surface proteins in Gram-negative bacteria. This mechanism, believed to contribute to virulence, has so far not been identified in a Gram-positive bacterium. In the genome of the Gram-positive human pathogen Streptococcus pyogenes, we identified pentanucleotide CRs within a putative signal s

The extant mammalian groups Monotremata, Marsupialia and Placentalia are, according to the ‘Theria’ hypothesis, traditionally classified into two subclasses. The subclass Prototheria includes the monotremes and subclass Theria marsupials and placental mammals. Based on some morphological and molecular data, an alternative proposition, the Marsupionta hypothesis, favours a sister group relationship

Popular Abstract in English Bolivia is the seventh richest country regarding biodiversity in the world. Also, in its territory more than 36 indigenous nations co-exist. Each of these has traditional medicines that are passed on from generation to generation orally. It has been estimated that the Bolivian flora has more than 20,000 plant species. Some of these are being explored for their pharmaceuColon cancer is common in both developed and developing countries, and is responsible for at least 600,000 deaths globally every year. It is therefore the second most common cause of cancer-related mortality. Extensive studies are being conducted worldwide to find more effective drugs that can be used in cancer treatment. In these studies, phytochemicals have proven to be good sources for drug dis

Popular Abstract in English From the pure technological perspective (leaving the business aside), the design of electronic devices, such as mobile phones, is an extremely complex process often involving a large number of disciplines, from mastering complicated mathematical models to proficiency of physical and electrical properties of specific materials involved in the manufacturing. In order to oThe methodology behind this work has been to use the concept of algorithm-hardware co-design to achieve efficient solutions related to the digital front-end in mobile receivers. It has been shown that, by looking at algorithms and hardware architectures together, more efficient solutions can be found; i.e., efficient with respect to some design measure. In this thesis the main focus have been plac

Differences in technological traditions we find between Neanderthals and anatomically modern humans has long been debated. It is important to discuss whether the differences in the handling of flint and other raw materials between the two populations . The use of raw materials are obviously directly related to the production of tools used to acquire food . Besides the quality of the material, also

Inom fastighetsrätten är begreppet fastighet centralt. Fastighetsrätten utgår ibland från fastighet och ibland från andra begrepp så som brukningsenhet, tomt och värderingsenhet. Ibland används begreppen som synonymer till fastighet vilket försvårar tolkningar av diverse lagar. Jordabalken definierar vad en fastighet är och fastighetsbildningslagen anger hur fastigheter bildas och ändras. Plan- oIn Swedish real estate law, the concept of real property is central. Real estate law sometimes refers to real property and sometimes to other concepts such as farm unit, plot, and valuation unit. Sometimes the terms are used as synonyms for real property, which complicates the interpretation of various laws due to conceptual confusion. An example of conceptual confusion is when owners of real pro

Vårdnadsreglerna, framför allt regleringen om gemensam vårdnad, har gjort en omfattande utvecklingsresa från 1970-talet och framåt. Uppsatsen syftar till att belysa, med en rättsdogmatisk metod, vilka förändringar som gjorts och vilket perspektiv som ligger bakom dem. Regleringen har gått från att gemensam vårdnad enbart var aktuellt för gifta föräldrar, till en presumtion om att gemensam vårdnad The Swedish custody regulations can be found in the Children and Parents Code. These rules have gone through a huge development during the modern times. This essay aims to illustrate which changes has been made and the perspectives behind them. The regulation has gone from joint custody for married parents only, to a presumption that joint custody always shall apply and on to that the custody shal

This research aimed to explore the experiences of Lagos State residents during COVID-19 and the relationship between COVID-19 reportage in Lagos State and ethnic inter-relationship. The goal is to understand media influence in a society from the perspectives of people directly influenced by the COVID-19 media frames. This thesis is the first research to explore ethnic polarization in Lagos State w

Barnkonventionens artikel 3 och 12 ger uttryck för två centrala principer inom barnrätten, vilka även är fastställda i andra svenska lagar som föräldrabalken och lagen med särskilda bestämmelser om vård av unga. Principen om barnets bästa innebär att vid samtliga åtgärder som rör barn ska barnets bästa vara avgörande. Vid denna bedömning ska varje barn få chansen att uttrycka sina åsikter, vilka s

Studien behandlar ett tvärvetenskapligt område där både teorier inom miljövetenskap, miljöpsykologi, pedagogik, naturvägledning och landskapsarkitektur behandlas. En viktig slutsats i studien är att lekplatsen är en plats med många möjligheter i en urban miljö, den kan utgöra en plats där ekologiska värden får ta stor plats samtidigt som barnens utrymme till lek tillgodoses. Så jag vill genom dennChildren’s outdoor play and natural elements at public playgrounds is important in the urban society. In this study the Outdoor Play Environment in the municipality of Lund is evaluated with the use of eight perceived sensory dimensions in green urban spaces. The evaluation shows that public playgrounds has a potential to function as bridges between children and the natural environment with the he

Att undersöka stjärnor i infrarött är en relativt ny företeelse till skillnad från optisk astronomi (dvs. synligt ljus). Det var först på 60-talet med teleskopet Stratoscope II som man lyckades få spektra från stjärnor i infrarött (våglängder på runt 3 m), och upptäckte förekomsten av vatten i kalla röda jättar. Den bakomliggade problematiken till varför modern infraröd astronomi är så ungt är våThe advent of infrared astronomy, unlike optical astronomy that was developed over centuries, was delayed until the space age due to our own atmosphere acting as an efficient shield towards this radiation. With a lot of molecules (including water) emitting in the infrared region, it was first in the late 1990s that water no longer was deemed special and was observed in many cooler (K-M) giant star

This paper is designed to examine the validity of the CAPM model in the emerging markets. I took the Indian market to be the case in which we examine the applicability of this model and therefore I decided to perform the study on one of the biggest Indian markets; Bombay Stock Exchange. The SENSEX30 was chosen as the examined index and I performed the study on the 28 listed companies in the market