Sökresultat

During the past few years the focus on bioprocess monitoring and control has increased. An area still under intensive development is the sampling methods for efficient and rapid analysis during fermentations. In this thesis, an online-sampling and monitoring scheme was developed using the versatile automated continuous flow system (VersAFlo) for recombinant protein production. From the implementat

Digitalisation has had a profound effect on our society. Much of our daily lives revolve around digital errands that, providing we have the appropriate skills, provide us with innumerous conveniences. Unfortunately for those who do not have such competencies, these normal everyday tasks have become unmanageable and as a result of the McDonaldization of society there are very few places to which th

Prisons encourage criminal activity and have negative impacts on sentenced individuals according to studies. Meanwhile the three largest political parties in Sweden work towards implementing tougher sentences. The three largest parties have in common their position on law enforcement which disputes what the research is saying and as a consequence, the objective of achieving less criminal activity

The objective of this thesis was to contribute to the limited research that has been carried out concerning maxillary sinusitis in medieval Scania. The aspiration was to do an inclusive comparative osteological analysis of three skeletal materials and investigate whether there is a difference in prevalence among rural and urban individuals as well as between sex, age and if an aeitology was visibl

This study sought to explore the socio-economic impacts of stigmatization on young women (16-24) infected with HIV in Accra, Ghana (Ridge hospital). Qualitative study was performed with five young women 16-24 infected with HIV attending HIV clinic at Ridge hospital. Interviews were conducted to explore respondents’ perception of stigmatization and discrimination based on their HIV status and gende

Utsagor från vittnen är ett väsentligt inslag i en effektiv rättskipning. Hot och våld mot vittnen utgör därför ett stort hinder i det brottsbekämpande ar-betet. Om det allmänna inte kan erbjuda vittnen ett tillräckligt skydd vid så-dana angrepp, finns det risk att vittnen väljer att inte samarbeta med polisen, vilket i sin tur kan få till följd att grova brott förblir ouppklarade. I denna studie Statements by witnesses are an essential element of the efficient administra-tion of justice. The occurrence of serious forms of threats and violence to-wards witnesses and their relatives therefore constitutes a major impediment to the work in combating crime. If the public cannot offer witnesses suffi-cient protection from attacks, there is a risk that they will choose not to co-operate with the

In this thesis I have investigated drivers of European Equity Long/Short hedge funds by analyzing the risk and return of individual Equity Long/Short hedge funds in different market environments. The results show that there are few macroeconomic drivers that can consistently explain the risk and return of individual European Equity Long/Short hedge funds. Running multifactor regression models on e

The aim of this study was to gain a deeper understanding of how close relatives experience living with a person with mental illness. The focus of this study was how the relative is affected, the support they receive from the surrounding system, and what strategies they develop to manage the situation. To answer the questions of the study, we have used qualitative content analysis on six autobiogra

This thesis aims to test the effect of changing gender roles on fertility. Previous literature has suggested that moving towards gender equality in the household sphere can increase fertility. I test whether a more equal division of housework or gender-egalitarian attitudes affect fertility. Two country groups are analysed that are at different levels regarding fertility and female labour force pa

With rapid urbanization and an increasing share of anthropogenic greenhouse gas emissions from cities, low-carbon urban transformations are critical for mitigating climate change. Local climate networks have been recognized for their potential to govern such activities. However, less is known about how such networks are implemented and managed as well as their capacity to accelerate transformative

Migratory behaviour explains how individuals or populations perform their migration. In birds this can include nocturnal or diurnal flights, long or short flights as well as low or high flight altitudes and several other behaviours. These behaviours shift throughout the migratory journey and especially when crossing barriers (large geographical areas where birds might have difficulties to find res

The digestion of food is known to have significant hemodynamic and metabolic effects where many have not been fully investigated. The potential effect of food intake could be interesting both from a physiological point of view and from a methodological point of view, as it could affect when blood samples are collected. The objective of this study was to investigate the effect of food intake on 143

We acclimated two species of sculpin, the freshwater prickly sculpin (Cottus asper) and the closely related marine Pacific staghorn sculpin (Leptocottus armatus) to freshwater (similar to 0 g/L), brackish water (15 g/L), and seawater (30 g/L) for at least 4 wk and examined the relationships between respiration, ion regulation, gill morphology, and freshwater tolerance. The prickly sculpin successf

Protein D (PD) is a highly conserved 42 kDa surface lipoprotein found in all Haemophilus influenzae, including nontypeable (NT) H. influenzae. PD is involved in the pathogenesis of respiratory tract infections, in the context of which it has been shown to impair ciliary function in a human nasopharyngeal tissue culture model and to augment the capacity to cause otitis media in rats. A likely mecha

BACKGROUND: Transcatheter aortic valve implantation is an effective treatment for patients with aortic stenosis; however, complications related to paravalvular leakage (PVL) persist, including increased risk of mortality, cardiovascular mortality, and rehospitalisation. AIMS: We sought to evaluate the clinical outcomes and valve performance at 1 year in patients with severe aortic stenosis treated

Solid insulin formulations obtained by different methods of preparation were compared with respect to chemical stability and morphology. Spray- and freeze-drying, solution enhanced dispersion by supercritical fluids (SEDS) and precipitation into starch microspheres were the methods used for preparation of solid powders. The excipients applied were melezitose, starch, and sodium taurocholate. The s

After identifying an association between maternal Epstein-Barr virus (EBV) reactivation and acute lymphoblastic leukemia (ALL), the authors analyzed a nested case-control study within Finnish and Icelandic maternity cohorts with 7 million years of follow-up to confirm EBV's role in ALL. Offspring of 550,000 mothers were followed up to age 15 years during 1975-1997 by national cancer registries to

The reported prevalence of malnutrition in pediatric hospitals ranges from 15% to 30% of patients, with an impact on growth, morbidity and mortality. Major deficits in nutrition care have been highlighted in European hospitals, and the implementation of nutrition support teams (NSTs) has been suggested as a means to improve malnutrition diagnosis and nutrition care for hospitalized patients. This

Glutamate is loaded into synaptic vesicles by vesicular glutamate transporters (VGLUTs), and alterations in the transporters expression directly regulate neurotransmitter release. We investigated changes in VGLUT1 and VGLUT2 protein levels after ischemic and excitotoxic insults. The results show that VGLUT2 is cleaved by calpains after excitotoxic stimulation of hippocampal neurons with glutamate,

ObjectiveThe quality of cardiopulmonary resuscitation (CPR) affects outcomes from cardiac arrest, yet manual CPR is difficult to administer. Although mechanical CPR (mCPR) devices offer high quality CPR, only limited data describe their deployment, their interaction with standard manual CPR (sCPR), and the consequent effects on chest compression continuity and patient outcomes. We sought to descri