Filtyp
Osteoporosis is a major health problem affecting more than 75 million people throughout Europe, USA and Japan. Epidemiological studies have determined that both genetic and environmental factors contribute to the pathogenesis of osteoporosis. We have investigated the association between polymorphisms at the osteocalcin locus and variables linked to bone health. Osteocalcin provides a link between
Popular Abstract in English From the pure technological perspective (leaving the business aside), the design of electronic devices, such as mobile phones, is an extremely complex process often involving a large number of disciplines, from mastering complicated mathematical models to proficiency of physical and electrical properties of specific materials involved in the manufacturing. In order to oThe methodology behind this work has been to use the concept of algorithm-hardware co-design to achieve efficient solutions related to the digital front-end in mobile receivers. It has been shown that, by looking at algorithms and hardware architectures together, more efficient solutions can be found; i.e., efficient with respect to some design measure. In this thesis the main focus have been plac
Accurate and internationally comparable human papillomavirus (HPV) DNA genotyping is essential for HPV vaccine research and for HPV surveillance. The HPV Laboratory Network (LabNet) has designed international proficiency studies that can be issued regularly and in a reproducible manner. The 2011 HPV genotyping proficiency panel contained 43 coded samples composed of purified plasmids of 16 HPV typ
This paper presents an experimental study where the mechanical behaviour of single-dowel timber connections made of acetylated Scots pine is compared with the behaviour of connections made from untreated Scots pine. The main aim was to evaluate the influence of the acetylation on the connection brittleness and also to compare the experimental results to the design provisions of the current Europea
Popular Abstract in Swedish PAX FÖR MANETER! Evolutionen är den process som format det liv vi ser omkring oss. Ända sedan Darwins tid har man känt till att arter och djurgrupper uppstår genom att det finns en variation mellan individer och att då tillgångarna begränsas (såsom mat eller utrymme) blir det de bäst anpassade som överlever och fortplantar sig. Flercelliga djur har funnits på jorden i kDuring the course of evolution animal complexity and diversity is generated. The last couple of years it has become increasingly clear that morphologically diverse animals share a great deal of their genomic contents, and it must be the expression of regulatory genes in new setting, rather than the generation of new genes, that are fundamental for the generation of diversity. Basal phyla hold a ke
The frame story
takes place in a dystopian Europe, possibly some kind of European Union around 2050 – in a state of conflicts and decay. The protagonists are a retired general, Piscator (cf. Fisher King) and a former journalist, Perle Vaus (cf. Perlesvaus/Perceval/Parsifal). She lost her home because of a new genderrelated law and stays homeless with others, covered by the Saxon bridge.
Aims: Resuscitated out-of-hospital cardiac arrest (OHCA) patients who remain comatose after hospital arrival are at high risk of mortality due to anoxic brain injury. MicroRNA are small-non-coding RNA molecules ultimately involved in gene-silencing. They show promise as biomarkers, as they are stable in body fluids. The microRNA 9-3p (miR-9-3p) is associated with neurological injury in trauma and
Popular Abstract in Swedish Diabetes mellitus, kronisk njursjukdom samt aterosklerotisk hjärtsjukdom utgör de vanligaste orsakerna till hjärt-kärlsjukdom och för tidig dödlighet. Dessa sjukdomar har blivit ett stort världsomfattande hälsoproblem med ökande prevalens och incidens. Tidig identifiering av patienter som ligger i riskzonen for komplikationer, framförallt hjärt-kärl komplikationer, tordRisk stratification of patients with chronic kidney disease and atherosclerotic heart disease is crucial. Microalbuminuria (MA) is associated with an increased risk of kidney and cardiovascular (CV) death, especially in patients with diabetes. However, MA in many instances is not sensitive for disease outcome; for instance, not all diabetic patients with albuminuria progress to kidney failure, and
The kallikrein gene family (KLK1-KLK15) is the largest contiguous group of protease genes within the human genome and is associated with both risk and outcome of cancer and other diseases. We searched for copy number variants in all KLK genes using quantitative PCR analysis and analysis of inheritance patterns of single nucleotide polymorphisms. Two deletions were identified: one 2235-bp deletion
Context: The risk of many conditions, including prostate cancer, breast cancer, and osteoporosis, is associated with serum levels of sex steroids. Objective: The aim of the study was to identify genetic variations in sex steroid-related genes that are associated with serum levels of estradiol (E2) and/or testosterone in men. Design: Genotyping of 604 single nucleotide polymorphisms in 50 sex stero
Objective. While the prevalence of radiographic thumb carpometacarpal (CMC1) osteoarthritis (OA) is well-described, little is known about clinically symptomatic disease presenting to physicians for care. We sought to determine the prevalence of doctor-diagnosed CMC1 OA. Methods. Using health care data from Skane in southern Sweden (population 1.24 million), we identified all adults ages >= 20 year
Identical in situ dust detectors are flown on board the Galileo and Ulysses spacecraft. They record impacts of micrometeoroids in the ecliptic plane at heliocentric distances from 0.7 to 5.4 AU and in a plane almost perpendicular to the ecliptic from -79 deg to +79 deg ecliptic latitude. The combination of both Ulysses and Galileo measurements yields information about the radial and latitudinal di
In conventional synthetic transmit aperture imaging (STA) the image is built up from a number of low resolution images each originating from consecutive single element firings to yield a high resolution image. This lowers the frame rate and may result in motion artifacts. This paper, describes a method in which all transmitting centers can be excited at the same time and separated at the receiver
Cystinuria is an autosomal recessive disorder characterized by increased urinary excretion of cystine and dibasic amino acids, which cause recurrent stone formation in affected individuals. Three subtypes of cystinuria have been described (type I, II, and III): type I is caused by mutations in the SLC3A1 gene, whereas nontype I (II and III) has been associated with SLC7A9 mutations. Of the 53 pati
Background: Rat models of peritoneal dialysis (PD) are useful for studying the physiology of peritoneal transport and evaluating new osmotic agents. Intraperitoneal (IP) solute concentrations and their evolution over time are easy to measure, but IP volume (IPV) is not. Direct volumetric measurements are the "gold standard;' but they are expensive and do not allow for repetitive measurements in th
Inom läkarutbildningen vid Lunds universitet förekommer undervisning i samtalsmetodik under såväl den prekliniska som den kliniska delen. Under kursen i samhällsmedicin på termin 10 träffas grupper om sex till sju studenter och en gruppledare fyra gånger för att diskutera studenternas videoinspelade konsultationer. Vi har utvärderat detta moment genom en klassrumsenkät till samtliga studenter och At Lund University Medical School communication skills are taught during both the preclinical and clinical part of the medical programme. As part of the training during the 5th year the students are required to videotape at least one patient consultation at a local primary health care centre. The students then meet in groups of 6-7 participants and a group leader to watch the recorded consultation
Introduction: Complement activation is involved in rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and atypical hemolytic uremic syndrome (aHUS). Autoantibodies to complement inhibitor factor H (FH), particularly in association with deletions of the gene coding for FH-related protein 1 (CFHR1), are associated with aHUS. Methods: Autoantibodies against FH, factor I (FI) and C4b-bindin
Medlingsinstitutet är en alternativ konflikthantering där parterna ges möjlighet att påverka konfliktens lösning och att återställa lugnet parterna emellan. Transaktioner är inte alltid friktionsfria och situationer kan uppstå där en av parterna vill föra saken inför domstol. Det är inte ovanligt att ombud i dessa situationer hotar om stämning som en skrämseltaktik för att ge sin part en hävstång.The Mediation Institute is a form of dispute resolution alternative to the judicial process where the parties may impact with the process and can influence the outcome, all in the purpose of restoring the calm between the parties. Transactions are not always successful and may result in a dispute where one party is inclined to take the dispute to court. It is not unusual that a part’s lawyer uses
