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Changes in serum lipids and postprandial glucose and insulin concentrations after consumption of beverages with beta-glucans from oats or barley: a randomised dose-controlled trial

Objectives: To investigate side by side the effects on serum lipoproteins and postprandial glucose and insulin concentrations of beverages enriched with 5 or 10 g of beta-glucans from oats or barley. Design and setting: An 8-week single blind, controlled study with five parallel groups carried out at two centres under identical conditions. Interventions: During a 3-week run-in period all subject

Predominance of CIN versus MSI in the development of rectal cancer at young age.

BACKGROUND: Development of proximal and distal colorectal cancers involve partly different mechanisms associated with the microsatellite instability (MSI) and the chromosomal instability (CIN) pathways. Colorectal cancers in patients under 50 years of age represent about 5% of the total number of tumors and have been associated with an increased frequency of MSI tumors. However, MSI and CIN may pl

Regeneration of commercial SCR catalysts by washing and sulphation: effect of sulphate groups on the activity

The use of bio-fuels is becoming more important because of the environmental benefits associated with these fuels. Deactivation of SCR catalysts applied in bio-fuel plants is a major problem due to the high potassium content of bio-fuels and therefore, great potential lies in finding regeneration processes that can be used commercially. Exposing the catalyst surface to sulphate groups generated by

Age- and serogroup-related differences in observed durations of nasopharyngeal carriage of penicillin-resistant pneumococci

Using data from an ongoing Swedish intervention project, the observed durations of nasopharyngeal carriage of penicillin-nonsusceptible Streptococcus pneumoniae (PNSP) (MIC of penicillin G of >= 0.5 mu g/ml) stratified by both pneumococcal serogroup and age of the carrier were compared. The means and 95% confidence intervals (CIs) were estimated by fitting a gamma distribution to the observed dura

p33 (gC1q Receptor) Prevents Cell Damage by Blocking the Cytolytic Activity of Antimicrobial Peptides.

The innate immune system is the first line of defense against invading microbes. Its specificity relies a great deal on host pattern recognition molecules that sense pathogen-associated molecular patterns of the invading pathogen. However, full protection is not always guaranteed, and some early defense mechanisms involved in bacterial killing, such as the complement system, can also exert cytolyt

Stability and performance of cation vacant Fe3-x-yVx□yO4 spinel phase catalysts in methanol oxidation

A series of spinel type Fe-V-O phases were prepared with V/Fe atomic ratios ranging from 0 to 1 and were used for methanol oxidation to formaldehyde. X-ray powder diffraction shows that the basic spinel-type structure is retained after use of the samples in methanol oxidation. Compared with the freshly prepared samples, in and ex situ analyses of the samples with XANES show that both V and Fe are

Inverse modeling of European CH4 emissions 2001-2006

European CH4 emissions are estimated for the period 2001-2006 using a four-dimensional variational (4DVAR) inverse modeling system, based on the atmospheric zoom model TM5. Continuous observations are used from various European monitoring stations, complemented by European and global flask samples from the NOAA/ESRL network. The available observations mainly provide information on the emissions fr

Autism spectrum disorders and coexisting disorders in a nationwide Swedish twin study

Background: Evidence from twin and molecular genetic studies is accumulating that Autism Spectrum Disorder (ASD) shares substantial etiological factors with other disorders. This is mirrored in clinical practice where ASD without coexisting disorders is rare. The present study aims to examine the range of coexisting disorders in ASD in a genetically informative cohort. Methods: Parents of all Swed

Interdialytic weight gain and ultrafiltration rate in hemodialysis: Lessons about fluid adherence from a national registry of clinical practice

Excessive interdialytic weight gain (IWG) and ultrafiltration rates (UFR) above 10 mL/h/kg body weight imply higher morbidity and mortality. This study aimed to estimate the prevalence of high fluid consumers, describe UFR patterns, and describe patient characteristics associated with IWG and UFR. The Swedish Dialysis DataBase and The Swedish Renal Registry of Active Treatment of Uremia were used

Stroke plane angle controls leading edge vortex in a bat-inspired flapper

The present interest in micro air vehicles has given the research on bat flight a new impulse. With the use of high speed cameras and improved PIV techniques, the kinematics and aerodynamics of bats have been studied in great detail. A robotic flapper makes it possible to do measurements by systematically changing only one parameter at a time and investigate the parameter space outside the natural

Monitored versus experience-based perceptions of environmental change: evidence from coastal Tanzania

The impacts of climate change are likely to exacerbate many problems that coastal areas already face. In this study, we used multinomial logistic regression to examine human perception of climate change based on a cross-sectional survey of 1253 individuals in coastal regions of Tanzania. This was complemented with time series analysis of 50-year meteorological data. The results indicate that self-

Identification and Characterization of New Mechanisms in Vascular Estrogen Signalling.

Estrogen exerts vasculoprotective effects in different experimental settings through inhibition of vascular smooth muscle cell proliferation, stimulation of nitric oxide production and attenuation of inflammation. Although these estrogen-evoked beneficial effects have been attributed to estrogen receptor α (ERα), also ERβ and the novel ER GPR30/GPER1 probably play significant roles in vascular est

Immune tolerance induction in patients with hemophilia A

Replacement therapy with factor VIII (FVIII) concentrates has become the mainstay of treatment for hemophilia, but about 30% of patients with a severe disease develop neutralizing antibodies against FVIII, which can lead to treatment resistance and an increased risk of bleeding. Immune tolerance induction (ITI) overcomes the immune response to FVIII concentrates in the majority of patients. Severa

BCL2A1 is a lineage-specific antiapoptotic melanoma oncogene that confers resistance to BRAF inhibition

Although targeting oncogenic mutations in the BRAF serine/threonine kinase with small molecule inhibitors can lead to significant clinical responses in melanoma, it fails to eradicate tumors in nearly all patients. Successful therapy will be aided by identification of intrinsic mechanisms that protect tumor cells from death. Here, we used a bioinformatics approach to identify drug-able, "driver" o

The role of energy efficiency in the deregulated Swedish electricity market

Four years have passed since January 1996 when retail competition was introduced in the Swedish electricity market. These years have been characterized by a rapid restructuring of the electricity supply industry through mergers and acquisitions, lower electricity prices, and a search for new marketing strategies in the competitive market. General trends and the results of two market surveys, under

Evolution of eyes: Pax, gene duplications & morphology

Popular Abstract in Swedish PAX FÖR MANETER! Evolutionen är den process som format det liv vi ser omkring oss. Ända sedan Darwins tid har man känt till att arter och djurgrupper uppstår genom att det finns en variation mellan individer och att då tillgångarna begränsas (såsom mat eller utrymme) blir det de bäst anpassade som överlever och fortplantar sig. Flercelliga djur har funnits på jorden i kDuring the course of evolution animal complexity and diversity is generated. The last couple of years it has become increasingly clear that morphologically diverse animals share a great deal of their genomic contents, and it must be the expression of regulatory genes in new setting, rather than the generation of new genes, that are fundamental for the generation of diversity. Basal phyla hold a ke

Use of cognitive mapping in the diagnosis of tolerance failure

The management of construction tolerances is a necessary and routine part of the construction activity and is normally brought to our attention only when failures are reported. In a study of tolerance management, the authors found widespread evidence of the same failures and the reasons for them. There seems to be no shortage of experience of the effects of failures in tolerances or of knowledge a

Renal failure occurs in chronic lithium treatment but is uncommon.

We sought to establish the prevalence of lithium-induced end-stage renal disease in two regions of Sweden with 2.7 million inhabitants corresponding to about 30% of the Swedish population. Eighteen patients with lithium-induced end-stage renal disease were identified among the 3369 patients in the general lithium-treated population, representing a sixfold increase in prevalence compared with the g