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1.79–1.75 Ga mafic magmatism of the Siberian craton and late Paleoproterozoic paleogeography

The paper presents new geological, geochronological, geochemical, and Nd isotopic data on the late Paleoproterozoic dolerites of the Siberian craton. U-Pb baddeleyite ages of the Doros dolerites (Aldan shield, south-eastern Siberia) and East Anabar dolerites (Anabar shield, northern Siberia) are 1757 ± 4 and 1774 ± 6 Ma, respectively. This new geochronological data together with published 1.76–1.7

Ozonation of 14C-labeled micropollutants – mineralization of labeled moieties and adsorption of transformation products to activated carbon

Ozonation transformation products (OTPs) are largely unknown compounds that are formed during the ozonation of micropollutants, and it is uncertain to which extent these compounds can be removed by subsequent adsorption to activated carbon. Thus, 14C-labeled micropollutants were ozonated to generate 14C-labeled OTPs, for which the adsorption of the sum of all 14C-labeled OTPs to activated carbon c

Knee replacement revision: an international comparison

AbstractBackground and purpose: The need for knee replacement revision arises from a combination of patient, prosthesis and surgeon factors. Registry data can help study these relationships. Pooling data from multiple registries may increase both reliability and generalizability. The study aim was to gain a multi-national overview of knee replacement revision, to inform best-practice and improve o

Polygenic scores, diet quality, and type 2 diabetes risk : An observational study among 35,759 adults from 3 US cohorts

Background Bothgenetic and lifestyle factors contribute to the risk of type 2 diabetes, but the extent to which there is a synergistic effect of the 2 factors is unclear. The aim of this study was to examine the joint associations of genetic risk and diet quality with incident type 2 diabetes. Methods and findings We analyzed data from 35,759 men and women in the United States participating in the

Growing the seeds of pebble accretion through planetesimal accretion

We explore the growth of planetary embryos by planetesimal accretion up to and beyond the point at which pebble accretion becomes efficient at the so-called Hill-transition mass. Both the transition mass and the characteristic mass of planetesimals that formed by the streaming instability increase with increasing distance from the star. We developed a model for the growth of a large planetesimal (

Soccer after anterior cruciate ligament injury - An incompatible combination? A national survey of incidence and risk factors and a 7-year follow-up of 310 players

All players in Swedish soccer teams are required to have insurance in the same company. from the archives of the insurance company, all 3,735 injuries reported in 1986 in 188,152 Swedish soccer players were reviewed. of these, 937 were knee injuries. All players were asked by mail to fill in a questionnaire and 83 percent replied. the patient records from the different hospitals were requested. th

Spatial heterogeneity in repeated measures of perceived stress among car commuters in Scania, Sweden

BACKGROUND: Long commutes by car are stressful. Most research studying health effects of commuting have summarized cross-sectional data for large regions. This study investigated whether the levels of stress and individual characteristics among 30–60 min car commuters were similar across different places within the county of Scania, Sweden, and if there were changes over time. METHODS: The study p

Haemophilia B mutations in Sweden: a population-based study of mutational heterogeneity

The present series comprises all families (n = 77) with haemophilia B in Sweden and may be considered to be representative for the purposes of a population-based study of mutational heterogeneity. The 77 families (38 severe, 10 moderate, 29 mild) had 51 different mutations in total. Thirteen families had total, partial or small deletions, two had mutations in the promoter, eight families had splic

The practice of internal medicine in Europe: organisation, clinical conditions and procedures

Background: Current information on the role of internists in the European countries is scarce. This report describes the results of a survey of the practice of internists in Europe. Methods: Two online questionnaire-based surveys were carried out by the European Board of Internal Medicine, one on the practice of internists and the other on postgraduate training in internal medicine. The national i

Deep Reinforcement Learning Approach to Portfolio Optimization

This paper evaluates whether a deep reinforcement learning (DRL) approach can be implemented, on the Swedish stock market, to optimize a portfolio. The objective is to create and train two DRL algorithms that can construct portfolios that will be benchmarked against the market portfolio, tracking OMXS30, and the two conventional methods, the naive portfolio, and minimum variance portfolio. We eval

Optimization of aftermarket logistics with dual supply chains for Sandvik AB

Background: Aftermarket logistics is important for a manufacturing company to maintain customer satisfaction in the long run. However, the supply chain set for aftermarket parts is equally crucial as the original equipment. Modification or optimization of the logistics systems for slow-moving aftermarket items is inevitable. Sandvik, an engineering company in the mining industry is now interested

Structural Modelling of Credit Spreads on the European Bond Market: An Empirical Study

In a growing global corporate bond market, insights and understanding of the markets pricing mechanisms becomes increasingly important to investors. While previous research on credit risk has mainly focused on the American bond market, European bonds remain rather unexplored in academia. In this article, we investigate the explanatory power of a family of credit risk models - called structural modThis thesis empirically tests the explanatory power of structural models on the European corporate bond market. Using new evaluation methods, including LASSO and gradient boosting regression, we can provide an in-depth assessment of the models’ shortcomings. With these tools we show that the structural models tend to systematically overstate or understate the spread due to an oversensitivity to le

A Mega Impact on a Nanoscale

In nature, for example through mechanical degradation (e.g., plastic waste in the sea) and through the exposure to UV-radiation, plastics can degrade to microplastics and eventually to even smaller plastic nanoparticles. Studies performed under laboratory conditions have shown that plastic nanoparticles can accumulate in the liver and the brain of fishes, hence plastic nanoparticles can cause brai

Divergence in coding sequence of different functional categories of immune genes between species of the order Rodentia

How mice avoid diseases, a measure of divergence The response we have to diseases vary from person to person. In much the same way diseases affect and are battled in many different ways depending on the species. This happens due to differences in their immune system. So, what causes these differences? Well, they are mostly caused by differences in the DNA, the molecule which has the code for ever

Autism spektrum störning & KBT interventioner En litteraturstudie om barn och unga med ASD och social ångest

Barn och ungdomar med autismspektrumstörning (ASD) löper större risk att uppleva ångestsymtom av olika slag. Tidigare studier har visat att effekten av kognitiv beteendeterapi (KBT) kan minska ångest hos patienter med ASD. I denna litteraturöversikt har vi granskat den vetenskapliga och metodologiska kvaliteten i sju randomiserade kontrollerade studier (RKS), samt vilka KBT interventioner som kan Children and adolescents with Autism spectrum disorder (ASD) are at greater risk of experiencing anxiety symptoms of various kinds. Previous studies have shown the effect of Cognitive behavior therapy to help reduce anxiety in patients with ASD. In this literature review, we examine the scientific and methodological quality of seven randomized controlled trials (RCT), as well as which CBT interven

Purchasing practices of environmentally preferable transport services, Guidance to increased shipper considerations

Popular Abstract in Swedish Denna avhandling handlar om hur företag visar, och kan visa, miljöhänsyn vid upphandling av godstransporttjänster. Transporter är en starkt bidragande, och växande, faktor till många miljöproblem såsom den förstärkta växthuseffekten och hälsofarliga partiklar i luften. Behovet av transporter ökar ständigt till följd av exempelvis lokalisering av produktion till låglöneThe logistical activity of transport is one of the largest contributors to several environmental problems. One efficient and effective way to decrease the environmental impact from transports is to implement changes in the logistically related strategies and activities applied, such as the selection of transport suppliers. Consideration of the environmental aspect when purchasing transport servic

Passive knee muscle moment arms measured in vivo with MRI

OBJECTIVE: To determine moment arm lengths from seven knee muscles and the patellar tendon. The knee muscles were the biceps femoris, semitendinosus, semimembranosus, gracilis, sartorius, and the lateral and medial gastrocnemius muscles. DESIGN: The moment arms were calculated based on MRI measurements. BACKGROUND: Moment arm lengths of different muscles with respect to the joint centre of rotatio

Wår lärda Skalde-fru : Sophia Elisabet Brenner och hennes tid

Under 1680-talet trädde Sophia Elisabet Brenner fram som poet och blev snart känd och uppskattad för sina dikter vid olika tillfällen i livet. Tillfällesdiktningen var en flexibel genre som gav henne möjligheten att resonera om tidens aktuella frågor, till exempel kvinnans ställning i äktenskap och samhälle eller värderingen av det som var gammalt och fornt och det som var nytt. Hennes rykte spred

Mitogenomic relationships of placental mammals and molecular estimates of their divergences.

Molecular analyses of the relationships of placental mammals have shown a progressive congruence between mitogenomic and nuclear phylogenies. Some inconsistencies have nevertheless persisted, notably with respect to basal divergences. The current study has aimed to extend the representation of groups, whose position in the placental tree has been difficult to establish in mitogenomic studies. Both