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Synthetic glucocorticoids (GCs) are widely used in the variety of dosages for treatment of premature infants with chronic lung disease, respiratory distress syndrome, allergies, asthma, and other inflammatory and autoimmune conditions. Yet, adverse effects such as glucocorticoid-induced osteoporosis and growth retardation are recognized. Conversely, 2-oxoglutarate (2-Ox), a precursor of glutamine,

The term bibliotherapy is well known in several scientific fields as well as among practitioners in the US and in the UK, but in Sweden there seems to be a more modest use of the term as well as presence of practical bibliotherapeutic activity. On the other hand, some of the effects of reading that are commonly associated with bibliotherapy in the scientific literature seems to be similar to the e

Slår bekämpningsmedel ut vilda bin? Vi människor och andra djur är beroende av växter för att kunna leva. Från dem får vi mycket av vår mat och andra produkter som vi behöver i vardagen. De flesta växter är i sin tur beroende av pollinering för att kunna sätta frukt och reproducera sig. Bin är exempel på insekter som är väldigt viktiga pollinatörer. De står för ca 80 procent av all insektspolline

Det kan sägas att extraordinära rättsmedel och dess resningsregler i dagens rättegångsbalk 58 kap. härstammar från konungens förmånsrätt att bryta domar under 1100-talets högmedeltid. Begreppet rättskraft och behovet av att angripa lagakraftvunna domar slog inte igenom förrän i slutet av 1600-talet. Dåvarande regler tillämpades formellt inte vid brottmål, men kom ändå att i praktiken att göra det.One can say that the extraordinary remedies and their rules regarding the relief for a substantive defect in today’s Code of Civil Procedure (Section 58) originate in the king’s preferential right to annulate court decisions during the late middle ages in the 1100s. The concept of legal force and the need to impugn court decisions that have taken legal effect was not noticed before the end of the

Popular science summary: Predictive model for unbound brain-to-plasma concentration ratio Blood-brain barrier (BBB) is a dynamic interface evolved to protect the brain from exposure to toxic xenobiotics and to maintain homeostasis. Distribution of drugs across BBB is critical for any drug discovery project. A drug designed for a target in brain has to pass through the BBB in sufficient concentr

En övergång från traditionsprincipen till avtalsprincipen för att uppnå sakrättsligt skydd avseende köp av lösöre har diskuterats en längre tid. Traditionsprincipens innebörd kan sägas vara att en köpare uppnår sakrättsligt skydd då köparen har fått varan i sin besittning, eller annars avskurit säljaren från dennes rådighet över varan. I en nyligen presenterad utredning så föreslår LösöreköpskommiA frequently discussed topic among Swedish legal scholars is the Swedish system concerning perfection of rights in rem, i.e. the requirements which must be fulfilled if a purchaser or pledgee is to become protected against all third parties’ rights on the sellers or pledgors’ side. A new government committe proposes a legally defined principle of contract regarding purchases of goods, i.e. the p

Förevarande uppsats syftar till att utreda vilka drivkrafter som föregick och motiverade rättsutvecklingen inom prostitutionslagstiftningen mellan åren 1850 och 1999. Därtill redogör uppsatsen för hur statsmaktens inställning gentemot prostitution och prostituerade kvinnor tog sig uttryck i den legisla-tiva utvecklingsprocessen. Arbetet har genomförts med hjälp av en rättshisto-risk metod för att This paper aims to investigate the driving forces that preceded and motivated the developments of the law in legislation concerning prostitution between the years of 1850 and 1999 in Sweden. Further more, the paper describes how the state's attitude towards prostitution and prostituted women was expressed in the legislative development process. The work has been undertaken using a legal-histor

Varför sätter vi i Sverige de flesta solcellerna på tak? Att producera el från solceller på tak är något som blir allt vanligare i Sverige. Men hur kostnadseffektivt är det att placera solceller på tak? Ett tak har tyvärr inte alltid en optimal vinkel mot solen vilket minskar el-produktionen. I länder som Rumänien och Bulgarien produceras nästan all solel från anläggningar på marken, vilket myckThe electricity produced from photovoltaics represents only a small fraction of the total electricity consumption in Sweden, but the installed capacity in Sweden doubled for the fourth year in a row in 2014. If this trend continues it is both interesting and important to discuss where we want to see PV systems in our future society. Looking at the market share of different types of PV systems in o

Formulating and implementing agricultural policies are important for the development of the agricultural sector and the rural population. The process of policy making is a political bargain between politicians and citizens. The outcome of this process, the policies, cannot be expected to be Pareto efficient resource allocations since altruistic behaviour is not very likely. All participants in the

Barnobesitas är sedan flera år ett ökat hälsoproblem bland barn. Obesitas vid 4 års ålder ger en kraftigt ökad risk för obesitas senare i livet. Att förebygga uppkomst och utveckling av obesitas är en långsiktig investering för framtiden. Idag finns ingen evidensbaserad metod för vägledning inom barnhälsovården för att främja hälsosamma levnadsvanor och förebygga obesitas hos förskolebarn. Det övePrevention of childhood obesity with its effects on children’s mental and physical health and well-being is an international public health priority and is suggested to be effective when started early. As Child Health Services lack an evidence-based model, there is the need for development of a low-intensive health promotion model that is feasible and cost-effective in preventing obesity in prescho

Objective Compare arthroscopic partial meniscectomy to a true sham intervention. Methods Sham-controlled superiority trial performed in three county hospitals in Denmark comparing arthroscopic partial meniscectomy to skin incisions only in patients aged 35-55 years with persistent knee pain and an MRIconfirmed medial meniscus lesion. A computer-generated table of random numbers generated two compa

Background: The SIOP-Renal Tumor Study Group (RTSG) does not advocate invasive procedures to determine histology before the start of therapy. This may induce misdiagnosis-based treatment initiation, but only for a relatively small percentage of approximately 10% of non-Wilms tumors (non-WTs). MRI could be useful for reducing misdiagnosis, but there is no global consensus on differentiating charact

Background Influenza and other respiratory viruses promote Streptococcus pneumoniae proliferation in the upper respiratory tract. We sought to investigate for what we believe is the first time, the effect of intranasal live attenuated influenza vaccine (LAIV) on nasopharyngeal S pneumoniae density in a low-income to middle-income country population with high pneumococcal carriage rates. Methods I

Governance issues surrounding technologies are profound. This is best illustrated in the context of climate change that does not only exert severe, pervasive and multifaceted impacts on the environment and on the everyday lives of people around the world, but also further aggravates the tension between law, technology and the public in a broader societal context. As a response to feckless global a

Automated cryptanalysis has seen a lot of attraction and success in the past decade, leading to new distinguishers or key-recovery attacks against various ciphers. We argue that the improved efficiency and usability of these new tools have been undervalued, especially for design processes. In this article, we break for the first time the classical iterative design paradigm for symmetric-key primit

The characteristics of an Elekta amorphous silicon (a-Si) electronic portal imaging device (EPID) in response to a 6 MV photon beam generated without a flattening filter, an unflattened beam, have been determined. The characteristics were then compared to those for a conventional photon beam generated with a flattening filter in the beam, a flattened beam, in order to determine the suitability of

The 4MOST consortium is currently halfway through a Conceptual Design study for ESO with the aim to develop a wide-field (>3 square degree, goal >5 square degree), high-multiplex (>1500 fibres, goal 3000 fibres) spectroscopic survey facility for an ESO 4m-class telescope (VISTA). 4MOST will run permanently on the telescope to perform a 5 year public survey yielding more than 20 million spectra at

This study aims to investigate and disentangle the impact of land use and climate variability on the Baltic Sea coastal zone from a millennial perspective. To assess the environmental status of the coastal zone we make use of siliceous microfossils (mainly diatoms), stable nitrogen and carbon isotopes, organic carbon accumulation rates, and lithological changes analyzed in a sediment core collecte