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Serum from normal blood-donors and juvenile diabetic patients inhibited Rb+ accumulation and stimulated release of 51Cr and insulin in suspensions of dispersed pancreatic islet cells prepared from ob/ob mouse islets, which are rich in B-cells. The effects indicate the presence of a B-cytotoxic factor in human serum. Serum from mouse and fetal calf also inhibited the islet cell accumulation of Rb+.
OBJECTIVES: Alcohol use disorders (AUD) is well known to aggregate in families and is associated with socioeconomic status (SES). The objective was to study the effect of education, income and neighborhood SES in adulthood on AUD, and to explore whether the potential associations were confounded by shared familial factors, by using a co-relative control design. METHODS: Data on AUD was drawn from
In 1944 Weiss & Taylor presented experimental evidence against "neurotropism" in nerve regeneration. We used a silicone Y-chamber system to repeat some of those experiments. The proximal stump of transected rat sciatic nerve was introduced into the proximal inlet of the Y. One of the distal outlets was left empty, plugged or occupied by a tendon graft, the other outlet being occupied by a nerv
Climate change impacts are a key challenge for sustainable urban development. To address this challenge, ecosystem-based adaptation (EbA), i.e., the use of ecosystem services and biodiversity to help people adapt to climate change, is increasingly being considered as an alternative or complement to traditional, engineering-based approaches (increasingly also known as nature-based solutions). Howev
The fields of human genetics and genomics have generated considerable knowledge about the mechanistic basis of many diseases. Genomic approaches to diagnosis, prognostication, prevention and treatment – genomic-driven precision medicine (GDPM) – may help optimize medical practice. Here, we provide a comprehensive review of GDPM of complex diseases across major medical specialties. We focus on tech
BACKGROUND: Knowledge is scarce on how needs for home help and special housing evolve among older people who begin to receive support from municipal social care. The purpose of this study was to describe baseline distributions and transitions over time between levels of dependency among older persons after being granted social care in a Swedish municipality.METHODS: Based on a longitudinal cohort
For the past 30 to 40 years, well before the concept of sustainable development became politically correct, regulation of the environment has been covered by Environmental Protection Agencies worldwide. Perhaps one of the most important things that we have learned is that regulations have significant costs, not just benefits, and that analysis of the cost and benefit of proposed rules is an indisp
Pulse wave velocity is an established marker of early vascular aging but may also help identifying individuals with supernormal vascular aging. We tested the hypothesis that individuals with the largest difference (Δ-age) between chronological and vascular age show the lowest rate of cardiovascular events and may thus be defined as supernormal vascular aging. Vascular age was defined as the predic
The aim of this study was to explore parents’ experiences of sleep and rest while admitted to hospital together with their ill child. When a child is hospitalized, it can be a traumatic experience for the entire family. Adaptation to the new situation and new parental responsibilities is necessary. Hospitalized children demand more supervision and care, making sleep disturbance a common challenge
BACKGROUND: Registry-based randomized clinical trials have emerged as useful tools to provide evidence on the comparative efficacy and safety of different therapeutic strategies. However, it remains unknown whether the results of registry-based randomized clinical trials have a sizable impact on daily clinical practice. We sought, therefore, to describe the temporal trends in thrombus aspiration (
Background: Early conversations about patients’ goals and values improve care, but clinicians struggle to conduct them. The systems-based Serious Illness Care Program (SICP) helps clinicians have more, better, and earlier conversations. Central to this approach is a clinician conversation guide for patient encounters. While the SICP works for practicing clinicians, it has not been tested with medi
The Norwegian TV-series named SKAM became extremely popular all around the world in 2017. The same year the last season premiered. The main character in this season is named Sana. The theme in the last season is Sana’s Muslim religiosity and how her Muslim identity is problematized in relation to the Norwegian society. The purpose of this essay is to explore the way SKAM portraits and problematize
The demand for high data rates in a wireless communication system has experienced a remarkable growth over the last years. This demand is continually increasing with the growing number of wirelessly connected devices. Thus, there is a continuing hunt for increasing the data transmission rate in wireless communication systems. To increase the data rate, the modern wireless communication system cann
This report has been conducted to examine the advantages and disadvantages of using an open system for experiments in the cone calorimeter with a vitiated air enclosure at low oxygen levels. Eight different experimental set-ups were conducted in which two were designed according to ISO 5660, i.e. the cone calorimeter in its standard configuration. In the other experimental set-ups, a chamber which
How young women with depression experience attitudes from other people - four anecdotes interpreted from a lifeworld perspective The aim of this master thesis was to, through a lifeworld perspective, understand how young women with some form of depression, experience other people’s negative attitudes towards depression. Using a hermeneutic phenomenological method, as described by Max van Manen, f
Allmänt känt hos många jurister – om inte alla – är att allmän domstol använder sig av vissa utarbetade modeller eller metoder då den har att utföra en tolkningsoperation på ett avtal. Dessa metoder underlättar för tolkaren att uppvisa enhetlighet i bedömningen så att lika avtal tolkas lika. Detta är även önskvärt då det leder till ett visst mått av förutsägbarhet. Allmänna reklamationsnämnden är
The company, Aimpoint, most important products are red dot sights which are produced in Malmö and Gällivare. These production plants had a demand of doubling their production capacity during 2003 and during 2004 there is a demand of additionally doubling the capacity. The purchasing department has been under large pressure due to the great increase in production volume. Much of the present work at
Trade marks perform a variety of economic functions in a commercial environment and plays an important role in a market economy. Therefore, there is a need to protect the distinguishing of competing goods and services offered by undertakings and accordingly to avoid consumer confusion. The origin function of the trade mark guarantees that all products bearing a trade mark emanate from the same com
Web 2.0, popularly known as social media is gaining attention from organizations as a tool for capturing the tacit knowledge of employees. Social media has been highly successful in the internet which has gained it this attention. However, organizations, which employ social media inside have faced many hurdles to making them a success in meeting their goals. This does not mean that social media is
This thesis examines Swedish relation to the EU’s 2020 goal in terms of energy efficiency and renewable resources. In 2010 EU came up with a new unified goal for all member states. One of the five targets concerns environment: until 2020 every member state should increase its energy efficiency with 20%; the total amount of energy production came from renewable resources should be 20% as well. Swed
