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Diabetic muscle atrophy is an inflammation-related complication of type-2 diabetes mellitus (T2DM). Even though regular exercise prevents further deterioration of atrophic status, there is no effective mediator available for treatment and the underlying cellular mechanisms are less explored. In this study, we investigated the therapeutic potential of MCC950, a specific, small-molecule inhibitor of

Introduction Atrial fibrillation (AF) is a major risk factor for ischaemic stroke and transient ischaemic attack (TIA), and AF detection can be challenged by asymptomatic and paroxysmal presentation. Long-term ECG monitoring after ischaemic stroke or TIA is recommended by all major societies in cardiology and cerebrovascular medicine as a secondary prophylactic measure. However, data on stroke red

BACKGROUND: Centrally inserted central catheters (CICCs) are indispensable in modern healthcare, but unfortunately, come with complications. Catheter-related thrombosis is a well-known complication reported to occur in 5-30% of patients with CICC. There is a paucity of studies that report the incidence of catheter-related thrombosis after the introduction of real-time ultrasound insertion guidance

Atmospheric aerosol particles serving as cloud condensation nuclei (CCN) are key elements of the hydrological cycle and climate. We have measured and characterized CCN at water vapor supersaturations in the range of S=0.10-0.82% in pristine tropical rainforest air during the AMAZE-08 campaign in central Amazonia. The effective hygroscopicity parameters describing the influence of chemical composit

Background: Chronic Pseudomonas aeruginosa (PA) infection causes increased morbidity and mortality in cystic fibrosis (CF). This study aimed to answer the following questions: Does the prevalence of chronic infection with PA differ between the CF centres in Scandinavia? Which differences exist concerning segregation and treatment of PA? Methods: 989 patients (86%) from all eight CF-centres in Scan

BackgroundThe greatest potential to reduce the burden of stroke is by primary prevention of first-ever stroke, which constitutes three quarters of all stroke. In addition to population-wide prevention strategies (the mass' approach), the high risk' approach aims to identify individuals at risk of stroke and to modify their risk factors, and risk, accordingly. Current methods of assessing and modif

Popular Abstract in Swedish Patienter som drabbats av Parkinsons sjukdom (PD) saknar förmågan att medvetet kontrollera sina rörelser. Livslång medicinering krävs, vilket lindrar symptomen och leder till att rörelsemönstret förbättras, men med varierad effektivitet. Trots att de läkemedel (t ex L-DOPA) som finns tillgängliga idag har fantastisk effekt, minskar deras effektivitet i takt med att sjukParkinson’s disease (PD) is a neurodegenerative disorder characterised by motor deficits such as slowness in movement, difficulty in initiating movement and tremor at rest. The cause of these motor symptoms is the selective loss of mesencephalic dopaminergic (mesDA) neurons, located in the substantia nigra (SN). These neurons project axons to the striatum where they release dopamine, a neurotransm

Musculoskeletal disorders are very common and affects the individual by pain and functional impairment, and the society through work disability and healthcare utilisation. To what extent is less studied. Routinely collected healthcare registers is a potential resource for epidemiological studies of musculoskeletal disorders. Skåne region, as opposed to nationally in Sweden, has healthcare register

Aim: To evaluate survival after out-of-hospital cardiac arrest in relation to sex. Methods: All patients with out-of-hospital cardiac arrest included in the Swedish Cardiac Arrest Registry between 1990 and 2000 in whom cardiopulmonary resuscitation (CPR) was attempted and who did not have a crew witnessed arrest were included. The registry covers 85% of the inhabitants of Sweden (approximately 8 m

BACKGROUND: Deep sternal wound infection is a serious and potentially lethal complication of cardiac surgery when performed through a median sternotomy. We describe the outcome of a new treatment strategy with C-reactive protein level-guided vacuum-assisted closure used at our department. METHODS: Data from 16 consecutive adult patients who had deep sternal wound infections after cardiac surgery w

Popular Abstract in Swedish Den i Malmö verksamme arkitekten Harald Boklund (1868-1924) är avhandlingens huvudperson. Vi får följa hans liv och verksamhet från direktörsvåningen på Konstakademien i Stockholm, över studie- och praktikåren i kejsartidens Berlin och det produktiva kompanjonskapet med August Lindvall i industrialismens Malmö till hans roll som föreningsmänniska, arkitekt, kritiker ochThe major part of this thesis is dedicated to a biography of the Swedish architect Harald Boklund (1868-1924), but also deals with the problematic concepts of cosmopolitism, regionalism and National romanticism i Scanian architecture 1890-1930. Harald Boklund was the son of Johan Boklund, a famous painter and director of the Swedish Academy of Fine Arts in Stockholm. Harald Boklund got his educati

Apolipoprotein M (apoM) is a novel apolipoprotein presented mostly in high-density lipoprotein (HDL) in human plasma, and is exclusively expressed in liver and in kidney. The pathophysiological function of apoM has not yet been elucidated. Apolipoprotein B (apoB), the characteristic apolipoprotein of low-density lipoprotein (LDL), is like apoM, a very hydrophobic protein, and thereafter they both

BACKGROUND: Patients with inflammatory joint diseases tend due to new treatments to be more physically active; something not taken into account by currently used outcome measures. The Rheumatoid and Arthritis Outcome Score (RAOS) is an adaptation of the Knee injury and Osteoarthritis Outcome Score (KOOS) and evaluates functional limitations of importance to physically active people with inflammato

BACKGROUND: LDL cholesterol (LDL-C) is a modifiable cardiovascular disease risk factor. We used 3 LDL-C methods to study the agreement between fasting and postprandial LDL-C in type 2 diabetes (T2DM) patients. METHODS: We served 74 T2DM patients a standardized meal and sampled blood at fasting and 1.5, 3.0, 4.5, and 6.0 h postprandially. We measured LDL-C by use of modified beta quantification (MB

Background: Women with germline BRCA1 or BRCA2 (BRCA1/BRCA2) mutations are at very high risk of developing breast cancer, including asynchronous contralateral breast cancer (CBC). BRCA1/BRCA2 genes help maintain genome stability and assist in DNA repair. We examined whether the risk of CBC associated with radiation treatment was higher among women with germline BRCA1/BRCA2 mutations than among non

Popular Abstract in Swedish Den vanligaste dödsorsaken i västvärlden är hjärt-kärlsjukdom. Därför finns det ett stort intresse att undersöka vilka faktorer som är av avgörande betydelse för att vi ska utveckla t.ex ateroskleros (åderförkalkning). Spelar livsstil och matvanor någon roll eller är det helt och hållet genetiskt betingat? Utvecklingen av förebyggande åtgärder, operationsteknik och postMigration and proliferation of smooth muscle cells (SMC) are important events in the development of atherosclerosis and restenosis following angioplastic surgery. It is important to gain further knowledge about the mechanisms regulating SMC form and function in order to understand the underlying disease process. In this thesis I have used cultured rat aortic SMC and analysed how these cells respon

OBJECTIVES: /st> Because standard immunosuppressive treatment for antineutrophil cytoplasm antibody-associated vasculitis (AAV) (granulomatosis with polyangiitis (Wegener's) (GPA) and microscopic polyangiitis (MPA)) has been associated with a significant risk of developing cancer, the cancer incidence of treated AAV patients was assessed. METHODS: /st> This analysis concerned 535 patients with new

Kai Söderhjelm (b. 1918 in Helsinki, d. 1996 in Gothenburg) belonged to a Finland-Swedish cultural family, and was for many years an important and valuable figure in the intellectual life of Sweden. Söderhjelm’s authorship follows the same clear thematic lines from his first book, Rid mot nordväst (1948; Ride to the northwest), to his last, Okänt land (1993; Unknown land). These themes are peace,

In Danish literature from the early 1970s, it was suggested that the freedom of speech should have a preferred position in relation to other constitutional rights. In a case from the Norwe-gian Supreme Court in 1976, judicial review of the constitutionality of legislation was divided in three categories. Constitutional rules about the freedom and security of the individual should be supervised mos

Microsoft Word - HEKN11 fall 2018 provisional schedule.docx 1 FALL 2018 CULTURE, ECONOMY AND ECOLOGY (HEKN11) PROVISIONAL SCHEDULE TEACHERS: Ellen Fall (EF) – Ellen.Fall@sambib.lu.se Alf Hornborg (AH) – Alf.Hornborg@hek.lu.se Andreas Malm (AM) [course coordinator] – Andreas.Malm@hek.lu.se Thomas Malm (TM) – Thomas.Malm@hek.lu.se Vasna Ramasar (VR) – Vasna.Ramasar@lucsus.lu.se All classes to be hel

https://www.keg.lu.se/sites/keg.lu.se/files/hekn11_fall_2018_schedule.pdf - 2026-04-27